Current management of asthma patients with corticosteroid resistance

American Journal of Respiratory and Critical Care Medicine

Volumn 154, Issue 2 SUPPL., 1996, Pages

  Busse, William W ^a,b   McGill, Kelly ^a   Jarjour, Nizar N ^a  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

^b University of Wisconsin Health   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BECLOMETASONE; BUDESONIDE; CORTICOSTEROID; CYCLOSPORIN; IMMUNOGLOBULIN; IMMUNOGLOBULIN G; METHOTREXATE; PREDNISONE;

ASTHMA; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DNA SYNTHESIS; FORCED EXPIRATORY VOLUME; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOMODULATION; LYMPHOCYTE PROLIFERATION; META ANALYSIS; NAUSEA; PRIORITY JOURNAL; REVIEW; STOMATITIS;

EID: 0029739772     PISSN: 1073449X     EISSN: None     Source Type: Journal    
DOI: 10.1164/ajrccm/154.2_pt_2.s70     Document Type: Review

References (16)

1. Sher, E. R., D. Y. M. Leung, W. Surs, J. C. Kam, G. Zieg, A. K. Kamada, and S. J. Szefler. 1994. Steroid-resistant asthma, cellular mechanisms contributing to inadequate response to glucocorticoid therapy. J. Clin. Invest. 93:33-39.
2. Corrigan, C. J., P. H. Brown, N. C. Barnes, S. J. Szefler, J.-J. Tsai, A. J. Frew, and A. B. Kay. 1991. Corticosteroid resistance in chronic asthma. Glucocorticoid pharmacokinetics, glucocorticoid receptor characteristics, and inhibition of peripheral blood T cell proliferation by glucocorticoids in vitro. Am. Rev. Respir. Dis. 144:1016-1025.
3. Corrigan, C. J., P H. Brown, N. C. Barnes, J.-J. Tsai, A. J. Frew, and A. B. Kay. 1991. Glucocosteroid resistance in chronic asthma: peripheral blood T lymphocyte activation and comparison of the T lymphocyte inhibitory effects of glucocosteroids and cyclosporine A. Am. Rev. Respir. Dis. 144:1026-1032.
4. Christophidis, N. 1984. Methotrexate. Clin. Rheum. Dis. 10:401-415.
5. Cream, J. J., and D. S. Pole. 1980. The effect of MTX and hydroxyurea on neutrophil chemotaxis. Br. J. Dermatol. 120:557.
6. Mullarkey, M. F., B. A. Blumstein, W. P. Andrade, G. A. Bailey, I. Olason, and C. F. Wetzel. 1988. Methotrexate in the treatment of corticosteroid-dependent asthma. N. Engl. J. Med. 318:603-607.
7. Mullarkey, M. F., J. K. Lammert, and B. A. Blumenstein. 1990. Long-term methotrexate treatment in corticosteroid-dependent asthma. Ann. Intern. Med. 112:577-581.
8. Dyer, P. D., T. R. Vaughan, and R. W. Weber. 1991. Methotrexate in the treatment of dependent asthma. J. Allergy Clin. Immunol. 88: 208-212.
9. Shiner, R. J., A. J. Nunn, K. F. Chung, and D. M. Geddes. 1990. Randomized, double-blind, placebo-controlled trial of methotrexate in steroid-dependent asthma. Lancet 336:137-140.
10. Erzurum, S. C., J. A. Leff, J. E. Cochran, L. M. Ackerson, S. J. Szefler, R. J. Martin, and G. R. Cott. 1991. Lack of benefit of methotrexate in severe, steroid-dependent asthma. Ann. Intern. Med. 114: 353-360.
11. Coffey, M. J., G. Sanders, W. L. Eschenbacher, A. Tsien, S. Ramesh, R. W. Weber, G. B. Toews, and W. J. McCune. 1994. The role of methotrexate in the management of steroid-dependent asthma. Chest 105:117-121.
12. Cirillo, R., M. Triggiani, L. Siri, G. R. Pettit, M. Condorelli, and G. Marone. 1990. Cyclosporin A rapidly inhibits mediator release from human basophils presumably by interacting with cyclophilin. J. Immunol. 44:3891-3897.
13. Lagente, V., C. Carre, F. Kvriacopoulos, E. Boichot, J. M. Mencia-Huerta, and P. Braquet. 1994. Inhibitory effect of cyclosporin A on eosinophil infiltration in the guinea-pig lung induced by antigen, platelet-activating factor and leukotriene B4. Eur. Respir. J. 7:921-926.
14. Szczeklik, A., E. Nizankowska, R. Dworski, B. Domagala, and G. Pinis. 1991. Cyclosporine for steroid-dependent asthma. Allergy 46:312-315.
15. Alexander, A. G., N. C. Barnes, and A. B. Kay. 1992. Trial of cyclosporine in corticosteroid-dependent chronic severe asthma. Lancet 339: 324-328.
16. Mazer, B. D., and E. W. Gelfand. 1991. An open-label study of high-dose intravenous immunoglobulin in severe childhood asthma. J. Allergy Clin. Immunol. 87:976-983.