Progesterone, oestradiol and oxytocin and their in vitro effect on maintaining the number of gap junction plaques in human myometrium at term

Acta Physiologica Scandinavica

Volumn 157, Issue 4, 1996, Pages 461-469

  Kilarski, W M ^a,b   Fu, X ^b   Backstrom T ^c   Roomans, G M ^b,c   Ulmsten, U ^b  

^a JAGIELLONIAN UNIVERSITY   (Poland)

^b UPPSALA UNIVERSITY   (Sweden)

^c UMEÅ UNIVERSITY   (Sweden)

Author keywords

Gap junctions; Human myometrium; Oestradiol; Oxytocin; Progesterone

Indexed keywords

ESTRADIOL; OXYTOCIN; PROGESTERONE;

ARTICLE; CELL JUNCTION; CONCENTRATION RESPONSE; CONFOCAL LASER MICROSCOPY; CONTROLLED STUDY; DRUG EFFECT; ELECTRON MICROSCOPY; FEMALE; HUMAN; HUMAN TISSUE; MUSCLE BIOPSY; MYOMETRIUM; PREGNANCY; PRIORITY JOURNAL;

EID: 0029739717     PISSN: 00016772     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-201X.1996.500247000.x     Document Type: Article

References (29)

1. Barnafi, L. & Larraguibel, R. 1974. The in vitro effect of progesterone and oestrogens on the spontaneous and oxytocin-induced activity of the human myometrium. Acta Endocrinol 76, 172-177.
2. Batra, S. 1986. Effect of oxytocin on calcium influx and efflux in the rat myometrium. Eur J Pharmacol 120, 57-61.
3. Bond, M., Kitazawa, T., Somlyo, A.P. & Somlyo, A.V. 1984. Release and recycling of calcium by the sarcoplasmic reticulum in guinea pig portal vein smooth muscle. J Physiol (Lond) 355, 677-659.
4. Ciray, H.N., Persson, B.E., Bäckström, T., Roomans, G.M. & Ulmsten, U. 1994. Direct intracellular injections for studying human myometrial gap junctions prior to labor. Acta Obstet Gynecol Scand 73, 97-102.
5. Cole, W.C. & Garfield, R.E. 1985. Alterations in coupling in uterine smooth muscle. In: D.C. Spray & M.V.L. Bennett (eds) Gap Junctions, pp. 215-230. Cold Spring Harbor Laboratory Press, New York.
6. Csapo, A.I. 1981. Force of labor. In: L. Iffy & H.A. Kaminetzky (eds) Principle and Practice of Obstetrics and Perinatology, pp. 761-799. John Wiley and Sons, New York.
7. Fu, X., Rezapour, M., Löfgren, M., Ulmsten, U. & Bäckström, T. 1993a. Unexpected stimulatory effect of progesterone on human myometrial contractile activity in vitro. Obstet Gynecol 82, 23-28.
8. Fu, X., Rezapour, M., Löfgren, M., Ulmsten, U. & Bäckström, T. 1993b. Antitachyphylactic effects of progesterone and oxytocin on term human myometrial contractile activity in vitro. Obstet Gynecol 82, 532-538.
9. Fu, X., Ulmsten, U., Bäckström, T. 1994. Interaction of sex steroids and oxytocin on term human myometrial contractile activity in vitro. Obstet Gynecol 84, 272-277.
10. Garfield, R.E. 1984. Myometrial ultrastructure and uterine contractility. In: S. Bottari, J.P. Thomas, A. Vokaer & R. Vokaer (eds) Uterine Contractility, p. 81. Masson, New York.
11. Garfield, R.E. 1985. Cell-to-cell communication in smooth muscle. In: A.K. Grover & E.E. Daniel (eds) Calcium and Contractility, pp. 143-173. Humana Press, Clifton, NY.
12. Garfield, R.E., Kannan, M.S. & Daniel, E.E. 1980a. Gap junction formation in myometrium: control by oestrogen, progesterone and prostaglandins. Am J Physiol 238, C81-C89.
13. Garfield, R.E., Merrett, D. & Grover, A.K. 1980b. Gap junction formation and regulation in myometrium. Am J Physiol 239, C217-C228.
14. Garfield, R.E., Sims, S. & Daniel, E.E. 1977. Gap junctions: their presence and necessity in myometrium during parturition. Science 198, 958-960.
15. Garfield, R.E., Sims, S., Kannan, M.S. & Daniel, E.E. 1978. Possible role of gap junctions in activation of myometrium during parturition. Am J Physiol 235, C168-C179.
16. Hanani, M. 1993. Discussion: are gap junctions necessary for cell to cell coupling of smooth muscle? an update. Can J Physiol Pharmacol 71, 625-626.
17. Harfst, E., Severs, N.J. & Green, C.R. 1990. Cardiac myocyte gap junctions: evidence for major connexon protein with an apparent relative mass of 70000. J Cell Sci 96, 591-604.
18. Kilarski, W.M., Severs, N.J., Gourdie, R.G., Rezapour, M., Bøckstrím, T., Roomans, G.M. & Ulmsten, U. 1993. Gap junction density in human myometrium at term revealed by an anti-peptide antibody and laser scanning confocal microscopy. Folia Histochem Cytobiol 31, 155-160.
19. Kilarski, W.M., Rezapour, M., Bäckström, T., Roomans, G.M. & Ulmsten, U. 1994. Morphometric analysis of gap junction density in human myometrium at term. Acta Obstet Gynecol Scand 73, 377-384.
20. Ley, C. & Ley, S. 1994. Expression of gap junction protein connexin-43 is increased in the human myometrium toward and with the onset of labor. Am J Obstet Gynecol 170, 788-795.
21. Löfgren, M. 1991. Progesterone in Human Parturition. Umeå Univ. Med. Dissertations. New series. 321, 1-7.
22. Löfgren, M. & Bäckström, T. 1992. Progesterone concentrations in maternal and fetal serum are lower during functional dystocia than in normal labor. Obstet Gynecol 79, 752-759.
23. Löfgren, M. & Backström, T. 1994. Continuous progesterone exposure associated with high contraction frequency in human term myometrial strips. Acta Obstet Gynecol Scand 73, 186-191.
24. Löfgren, M., Holst, J. & Bäckström, T. 1992. Effects of in vitro progesterone and two 5α-reduced progestins, 5α-pregnane-3,20-dione and 5α-pregnane-3α-ol-20-one, on contracting human myometrium at term. Acta Obstet Gynecol Scand 71, 28-33.
25. Mironneau, J. 1990. Ion channels and excitation-contraction coupling in myometrium. In: E.R. Garfield (ed.) Uterine Contractility, pp. 9-19, Serono Symposia, Norwell.
26. Roomans, G.M., Kilarski, W.M., Ciray, N., Persson, B.E., Bäckström, T., Ulmsten, U. 1993. Structural and functional studies of gap junctions in human myometrium. Eur J Morphol 31, 55-59.
27. Soloff, M.S. 1975. Uterine receptors for oxytocin; effects on oestrogens. Biochem Biophys Res Commun 65, 205-212.
28. Tabb, T.N. & Garfield, R.E. 1992. Molecular biology of uterine contractility. Clinic Obstet Gynecol 35, 494-504.
29. Thorburn, G.D. & Challis, J.R.G. 1979. Endocrine control of parturition. Physiol Rev 59, 863-918.