High-resolution structure of the diphtheria toxin repressor complexed with cobalt and manganese reveals an SH3-like third domain and suggests a possible role of phosphate as co-corepressor

Biochemistry

Volumn 35, Issue 38, 1996, Pages 12292-12302

  Qiu, Xiayang ^a,b   Pohl, Ehmke ^a   Holmes, Randall K ^c   Hol, Wim G J ^a,d  

^a UNIVERSITY OF WASHINGTON   (United States)

^b GLAXOSMITHKLINE   (United Kingdom)

^c UNIVERSITY OF COLORADO   (United States)

^d UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COBALT; DIPHTHERIA TOXIN; MANGANESE; PHOSPHATE; REPRESSOR PROTEIN; SULFATE;

ARTICLE; CONFORMATIONAL TRANSITION; CRYSTAL STRUCTURE; DNA BINDING; METAL BINDING; PRIORITY JOURNAL; PROTEIN DOMAIN; REPRESSOR GENE;

AMINO ACID SEQUENCE; BACTERIAL PROTEINS; BINDING SITES; COBALT; CRYSTALLOGRAPHY, X-RAY; DNA-BINDING PROTEINS; HYDROGEN BONDING; MANGANESE; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PHOSPHATES; PROTEIN CONFORMATION; PROTEIN FOLDING; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-ABL; PROTO-ONCOGENE PROTEINS C-FYN; SEQUENCE ALIGNMENT; SPECTRIN; SRC HOMOLOGY DOMAINS; SULFATES;

CORYNEBACTERIA; CORYNEBACTERINEAE;

EID: 0029739483     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi960861d     Document Type: Article

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