The atherogenic role of triglycerides and small, dense low density lipoproteins: Impact of ciprofibrate therapy

Atherosclerosis

Volumn 124, Issue SUPPL., 1996, Pages

  Chapman, M John ^a   Bruckert, Eric ^a  

^a PITIÉ SALPÊTRIÈRE HOSPITAL   (France)

Author keywords

Apolipoprotein B100; Atherogenic lipoprotein phenotype; Cholesteryl ester transfer; Ciprofibrate therapy; Combined hyperlipidaemia; Premature cardiovascular disease; Triglyceride rich lipoproteins

Indexed keywords

APOLIPOPROTEIN B; CIPROFIBRATE; LOW DENSITY LIPOPROTEIN; TRIACYLGLYCEROL;

ATHEROGENESIS; CHOLESTEROL BLOOD LEVEL; CONFERENCE PAPER; HYPERLIPIDEMIA; LIPID METABOLISM; LIPID TRANSPORT; PRIORITY JOURNAL; TRIACYLGLYCEROL BLOOD LEVEL;

EID: 0029739345     PISSN: 00219150     EISSN: None     Source Type: Journal    
DOI: 10.1016/0021-9150(96)05853-4     Document Type: Conference Paper

References (33)

1. Austin MA. Plasma triglyceride and coronary heart disease. Arteriosclerosis Thromb 1991;11:2.
2. Phillips NR, Waters D, Havel RJ. Plasma lipoproteins and progression of coronary artery disease evaluated by angiography and clinical events. Circulation 1993;88:2762.
3. Chapman MJ. Classification of the dyslipoproteinaemias: an update. Ann Nestlé 1994;52:1.
4. Patsch JR. Triglyceride-rich lipoproteins and atherosclerosis. Atherosclerosis 1994;110:524.
5. Tall AR. Plasma lipid transfer proteins. J Lipid Res 1986;27:361.
6. Havel RJ. The formulation of LDL: mechanisms and regulation. J Lipid Res 1984;25:1570.
7. Brown MS, Kovanen PJ, Goldstein JL. A receptor-mediated pathway for cholesterol homeostasis. Science 1981;212:628.
8. Koizumi J, Mabuchi H, Yoshimura A et al. Deficiency of serum cholesteryl-ester transfer activity in patients with familial hyperalphalipoproteinaemia. Atherosclerosis 1985;58:175.
9. Deckelbaum RJ, Granot E, Oschry Y, Rose L, Eisenberg S. Plasma triglyceride determines structure-composition in low and high density lipoproteins. Arteriosclerosis 1984;4:225.
10. Guerin M, Dolphin PJ, Chapman MJ. A new in vitro method for the simultaneous evaluation of cholesteryl ester exchange and mass transfer between HDL and ApoB-containing lipoprotein subspecies: identification of preferential cholesteryl ester acceptors in human plasma. Arteriosclerosis Thromb 1994;14:199.
11. Chapman MJ, Prassl R, Laggner P et al. LDL subfractions: properties and functions. Atherosclerosis 1994;109(abstr):350.
12. Nigon F, Lesnik P, Rouis M, Chapman MJ. Discrete subspecies of human low density lipoproteins are heterogeneous in their interaction with the cellular LDL receptor. J Lipid Res 1991;32:1741.
13. Goldstein JL, Brown MS. Familial hypercholesterolemia. In: Stanbury JB, Wyngaarden JB, Fredrickson JC, Goldstein JL and Brown MS. (eds.). The Metabolic Basis of Inherited Disease, 5th Edn. New York: MacGraw-Hill, 1983;672.
14. Grundy SM. Pathogenesis of hyperlipoproteinemia. J Lipid Res 1984;25:1611.
15. Anderson KM, Castelli WP, Levy D. Cholesterol and mortality. 30 years of follow-up from the Framingham study. J Am Med Assoc 1987;257:2176.
16. Tornvall P, Karpe F, Carlson LA, Hamsten A. Relationship of low density lipoprotein subfractions to angiographically-defined coronary artery disease in young survivors of myocardial infarction. Atherosclerosis 1991;90:67.
17. Swinkels DW, Demacker PN, Hendricks JC, Van't Laar A. Low density lipoprotein subfractions and relationship to other risk factors for coronary artery disease in healthy individuals. Arteriosclerosis 1989;9:604.
18. Crouse TR, Parks JS, Schey HM, Kahl FR. Lipoprotein molecular weight in human beings with coronary artery disease. J Lipid Res 1985;26:566.
19. Austin MA, Breslow JL, Hennekens CH, Burling JE, Willett WC, Krauss RM. Low density lipoprotein subclass patterns and risk of myocardial infarction. J Am Med Assoc 1988;260:1917.
20. Griffin BA, Freeman DJ, Tait GW, Thomson J, Caslake MJ, Packard CJ, Shepherd J. Role of plasma triglyceride in the regulation of plasma low density lipoprotein (LDL) subfractions: relative contribution of small, dense LDL to coronary heart disease risk. Atherosclerosis 1994;106:241.
21. Campos H, Genest JJ, Blijlevens E, et al. Low density lipoprotein particle size and coronary artery disease. Arteriosclerosis Thromb 1992;12:187.
22. Chapman MJ, Laplaud PM, Luc G, et al. Further resolution of the low density lipoprotein spectrum in normal human plasma: physicochemical characteristics of discrete subspecies separated by density gradient ultracentrifugation. J Lipid Res 1988;29:442.
23. Teng B, Sniderman AD, Soutar AK, Thomson GR. Metabolic basis of hyperapobetalipoproteinemia. Turnover of apolipoprotein B in low density lipoprotein and its precursors and subfractions compared with normal and familial hypercholesterolemia. J Clin Invest 1986;77:663.
24. Caslake MJ, Packard CJ, Gaw A, et al. Fenofibrate and LDL metabolic heterogeneity in hypercholesterolemia. Arteriosclerosis Thromb 1993;13:702.
25. Dejager S, Brückert E, Chapman MJ. Dense low density lipoprotein subspecies with diminished oxidative resistance predominate in combined hyperlipidemia. J Lipid Res 1993;34:295.
26. Anber V, Griffin BD, Packard CJ, Shepherd J. Preferential binding of small, dense LDL to human arterial proteoglycan. Atherosclerosis 1994;109(abstr):217.
27. Steinberg D, Parthasarathy S, Carew TE, et al. Beyond cholesterol. Modifications of low density lipoprotein that increase its atherogenicity. N Engl J Med 1989;320:915.
28. Krauss RM. Heterogeneity of plasma low-density lipo-proteins and atherosclerosis risk. Curr Opin Lipidol 1994;5:339.
29. Watts GF, Mandalia S, Brunt JV, Slavin BM, Coltart DJ, Lewis V. Independent associations between plasma lipoprotein subfraction levels and the course of coronary artery disease in the St. Thomas' Atherosclerosis Regression Study (STARS). Metabolism 1993;42:1461.
30. Krauss RM, Stampfer MJ, Blanche PJ, Holl LG, Ma J, Hennekens CH. A prospective study of LDL particle diameter and risk of myocardial infarction, AHA Meeting, Dallas, USA. Circulation 1994;90(Suppl 4,abstr 2469):I-460.
31. Bruckert E, Dejager S, Chapman MJ. Ciprofibrate therapy normalises the atherogenic low density lipoprotein subspecies profile in combined hyperlipidemia. Atherosclerosis 1993;100:91.
32. Mann CJ, Yen FT, Grant AM, Bihain BE. Mechanism of plasma cholesteryl ester transfer in hypertriglyceridemia. J Clin Invest 1991;88:2059.
33. Gaw A, Packard CJ, Caslake MJ, et al. Effects of ciprofibrate on LDL metabolism in man. Atherosclerosis 1994;108:137.