Fluorenone 1,4-dihydropyridine derivatives with cardiodepressant activity: Enantiomeric separation by chiral HPLC and conformational aspects

Chirality

Volumn 8, Issue 3, 1996, Pages 281-290

  Caccamese, Salvatore ^a   Chillemi, Rosa ^a   Principato, Grazia ^a  

^a UNIVERSITY OF CATANIA   (Italy)

Author keywords

1H NMR spectra; CD spectra; chiral stationary phases; Chiralpak AD; enthalpy; entropy; synperiplanar conformer of dihydropyridines

Indexed keywords

1,4 DIHYDROPYRIDINE 3,5 DICARBOXYLIC ACID DIETHYL ESTER; 1,4 DIHYDROPYRIDINE DERIVATIVE; FLUORENONE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CHIRALITY; CIRCULAR DICHROISM; DRUG CONFORMATION; ENANTIOMER; ENTHALPY; ENTROPY; HEART ARRHYTHMIA; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; NUCLEAR OVERHAUSER EFFECT; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE;

ANTI-ARRHYTHMIA AGENTS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DIHYDROPYRIDINES; MOLECULAR CONFORMATION; SPECTROPHOTOMETRY, ULTRAVIOLET; STEREOISOMERISM; THERMODYNAMICS;

EID: 0029739166     PISSN: 08990042     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1520-636X(1996)8:3<281::AID-CHIR8>3.0.CO;2-K     Document Type: Article

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