Molecular analysis of the leukaemic B cell in adult and childhood acute lymphoblastic leukaemia

British Journal of Haematology

Volumn 94, Issue 4, 1996, Pages 685-693

  Coyle, Luke A ^a   Papaioannou, Maria ^a   Yaxley, John C ^a   Chim, James S ^a   Attard, M ^a   Hoffbrand, A Victor ^a   Foroni, Letizia ^a  

^a ROYAL FREE HOSPITAL   (United Kingdom)

Author keywords

Adult and childhood ALL; CDR3; VH genes

Indexed keywords

IMMUNOGLOBULIN HEAVY CHAIN;

ACUTE LYMPHOBLASTIC LEUKEMIA; ADULT; ARTICLE; B CELL LEUKEMIA; CHILD; CONTROLLED STUDY; DNA FINGERPRINTING; FEMALE; GENE REARRANGEMENT; HUMAN; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL;

EID: 0029737426     PISSN: 00071048     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2141.1996.d01-1851.x     Document Type: Article

References (45)

1. Beishuizen, A., Hahlen, K., Hagemeijr, Verhoeven, M.J., Hoojikaas, H., Andriaansen, H.J., Wolvers-Tettero, I.L.M. van Wering, E.R. & van Dongen, J.J.M. (1991) Multiple rearranged immunoglobulin genes in childhood acute lymphoblastic leukemia of precursor B-cell origin. Leukemia, 5, 657-667.
2. Berman, J.E., Nickerson, K.G., Pollock, R.R., Barth, J.E., Schuurman, R.K.B., Knowles, D.M., Chess, L. & Alt, F. (1991) VH gene use in humans: biased use of the VH6 gene in immature B lymphoid cells. Euopean Jounal of Immunology, 21, 1311-1314.
3. Berman, J.E., Mellis, S.J., Pollock, R., Smith, C.L., Suh, H., Heinke, B., Kowal, C., Surti, U., Chess, L., Cantor, C.R. & Alt, F.W. (1988) Content and organisation of the human IgH VH locus: definition of three new VH families and linkage to the g CH locus. EMBO Journal, 7, 727-738
4. Billadeau, D., Quam, L., Thomas, W., Kay, N., Greipp, P., Kyle, R., Oken, M.M. & Van Ness, B. (1992) Detection and quatification of malignant cells in the peripheral blood of multiple myeloma patients. Blood, 80, 1818-1824.
5. Buluwela, L., Albertson, D.G., Sherrington, P., Rabbitts, P.H., Spurr, N. & Rabbitts, T.H. (1988) The use of chromosomal translocation to study the human immunoglobulin gene organisation: mapping DH segments within 35kb of the Cμ gene and identification of a new DH locus. EMBO Journal, 7, 2003-2010.
6. Campana, D., Coustan-Smith, E. & Janossy, G. (1990) Immunophenotyping in haematological diagnosis. Baillieres Clinical Haematology, 3, 889-919.
7. Campana, D. & Pui, C-H. (1995) Detection of minimal residual disease in acute leukemia: methodologic advances and clinical significance. Blood, 85, 1416-1434.
8. Chim, J.S., Coyle, L., Yaxley, J.C., Cole-Sinclair, M.F., Cannell, P.K., Hoffbrand, V.A. & Foroni, L. (1996) Investigation of minimal residual disease (MRD) by the use of a semi-quantitative multistep test combination in ALL. British Jounal of Heamatology, 92, 104-115.
9. Cole-Sinclair, M.F., Foroni, L. & Hoffbrand, A.V. (1994) Acute lymphoblastic leukaemia. Clinical Haematology, 7, 183-233.
10. Cole-Sinclair, M., Foroni, L., Wright, F., Mehta, A., Prentice, G. & Hoffbrand, A.V. (1993) Minimal residual disease in acute lymphoblastic leukaemia: PCR analysis of immunoglobulin gene rearrangements. Leukaemia and Lymphoma, 2, 49-58.
11. Cook, G.P. & Tomlinson, I.M. (1995) The human immunoglobulin. VH repertoire. Immunology Today, 16, 237-242.
12. Cook, G.P., Tomlinson, I.M., Walter, G., Riethman, H., Carter, N.P., Buluwela, L., Winter, G. & Rabbitts, T.H. (1994) A map of the human immunoglobulin VH locus completed by analysis of the telomeric region chromosome 14q. Nature Genetics, 7, 162-168.
13. Copeland, E.A. & McGuire, E.A. (1995) The biology and treatment of acute lymphoblastic leukemia in adults. Blood, 85, 1151-1168.
14. Cuisinier, G.V., Boubli, M., Fougerau, M. & Tonnelle, C. (1989) Preferential expression of the VH5 and VH6 immunoglobulin genes in early human B-cell ontogeny. Scandinavian Journal of Immunology, 30, 493-497.
15. Deane, M. & Hoffbrand, A.V. (1995) Detection of minimal residual disease in acute lymphoblastic leukemia. Leukemia: Advances, Research and Treatment (ed. by E. J. Freireich and H. Kantarjian). pp. 135-140. Kluwer Academic Publishers, Dordrecht.
16. Deane, M. & Norton, J. (1990) Immunoglobulin heavy chain variable region family usage is independent of tumour cell phenotype in human B lineage leukemias. European Journal of Immunology, 20, 2209-2217.
17. Deane, M. & Norton, J. (1991) Preferential rearrangement of developmentally regulated immunoglobulin VIII genes in human B-lineage leukemias. Leukemia, 5, 646-650.
18. Ebeling, S.B., Schutte, M.E., Akkermans-Koolhaas, K.E., Bloem, A.C., Gmelig-Meyling, F.H. & Logtenberg, T. (1992) Expression of members of the immunoglobulin VH3 gene families is not restricted at the level of individual genes in human chronic lymphocytic leukaemia. International Jounal of Immunology, 4, 313-320.
19. Foroni, L., Mason, P.J. & Luzzatto, L. (1990) Immunoglobulin and T-cell receptor gene analysis for the investigation of lymphoproliferative disorders. The Leukamic Cell (ed. by D. Catovsky), pp. 339-391. Churchill Livingstone, New York.
20. Ichihara, Y., Matsuoka, H. & Kurosawa, Y. (1988) Organisation of the human immunoglobulin heavy chain gene loci. EMBO Journal, 7, 4141-4150.
21. Ito, Y., Wasserman, R., Galili, N., Reichard, B.A., Shane, S., Lange, B. & Rovera, G. (1993) Molecular residual disease status at the end of chemotherapy fails to predict subsequent relapse in children with acute lymphoblastic leukaemia. Journal of Clinical Oncology, 11, 546-553.
22. Jonsson, O., Kitchens, R., Scott, F. & Smith, R. (1990) Detection of minimal residual disease in acute lymphoblastic leukemia using immunoglobulin hypervariable region specific oligonucleotide probes. Blood, 76, 2072-2079.
23. Kipps, T.J., Rassenti, L.Z., Duffy, S., Johnson, T., Kobayashi, R. & Carson, D.A. (1992) Immunoglobulin V gene expression in CD5 B-cell malignancies. Annals of the New York Academy of Sciences, 651, 373-383.
24. Kitchingman, G.R. (1993) Immunoglobulin heavy chain gene VH-D junctional diversity at diagnosis in patients with acute lymphoblastic leukemia. Blood, 81, 775-782.
25. Kitchingman, G.R. (1994) Residual disease detection in multiple follow-up samples in children with acute lymphoblastic leukemia. Leukemia, 8, 395-401.
26. Linke, B., Pyttlich, J., Tiemann, M., Suttorp, M., Paraweresch, R., Hiddemann, W. & Kneba, M. (1995) Identification and structural analysis of rearranged immunoglobulin heavy chain genes in lymphomas and leukemias. Leukemia 9, 840-847.
27. Logtenberg, T., Schutte, M.E., Ingirami, G., Berman, J.E., Gmelig-Mevling, F.H., Insel, R.A., Knowles, D.M. & Alt, F.W. (1989) Immunoglobulin VH gene expression in human B cell lines and tumors: biased VH gene expression in chronic lymphocytic leukemia. International Immunology, 1, 362-366.
28. Matsuda, F., Shin, E.K., Hirbayashi, Y., Nagaoka, H., Yoshida, M.C., Zong, S.Q. & Honjio, T. (1990) Organisation of the human immunoglobulin heavy chain: duplication of the D5 cluster within the locus and interchromosomal translocation of variable region segments. EMBO Jounal, 8, 2501-2506.
29. Mortari, F., Jin-Yi Wang & Schroeder, W., Jr (1993) Human cord blood antibody repertoire: mixed population of VH gene segments and CDR3 distribution in the expressed Cα and Cα repertoire. Jounal of Immunology, 150, 1348-1357.
30. Potter, M., Steward, C.G., Maitland, N. & Oakhill, A. (1992) Detection of clonality in childhood B-lineage acute leukemia by polymerase chain reaction. Leukemia, 6, 289-2894.
31. Potter, M.N., Steward, C.G. & Oakhill, A. (1993) The significance of detection of minimal residual disease in childhood acute lymphoblastic leukaemia. British Journal of Haematology, 83, 412-418.
32. + B cell chronic lymphocytic leukemia and displaying autoantibody activity. Blood, 82, 3103-3112.
33. Rassenti, L.Z. & Kipps, T.J. (1993) Lack of extensive mutations in the VH5 genes used in common B cell chronic lymphocytic leukaemia. Jounal of Experimental Medicine, 177, 1039-45.
34. Ravetch, J.V., Siebelist, U., Korsmeyer, S.J., Waldmann, T. & Leder, P. (1981) Structure of the human immunoglobulin m locus: characterisation of embryonic and rearranged D genes. Cell, 27, 584-591.
35. Rubestein, D.B., Schwartz, R.S., Guillaume, T., Leblanc, P. & Stewart, A.K. (1944) Germline complexity, restriction fragment length polymorphism, and coding region sequences of the human VH7 gene family identified with family-specific FR3 segment oligonucleotides. Molecular Immunology, 31, 713-721.
36. Sanz, I. (1991) Multiple mechanisms participate in the generation of diversity of human H chain CDR3 regions. Journal of Immunology, 147, 1720-1729.
37. Schroeder, H.W., Hillson, J.L. & Perlmutter, R.M. (1987) Early restriction of the human antibody repertoire. Science, 238, 791-793.
38. Sonntag, D., Weingartner, B. & Grutzamann, R.A. (1984) A member of a novel human DH gene family: DFHL16. Nucleic Acids Research, 17, 1267.
39. Steenbergen, E.J., Verhagen, O.J., van Leeuwen, E.F., van dem Borne, A.E. & van der Schoot, C.W. (1993) Distinct ongoing Ig heavy chain rearrangement processes in childhood B-precursor acute lymphoblastic leukemia. Blood, 82, 581-590.
40. Steward, C., Potter, M. & Oakhill, A. (1992) Third complementarity determining region (CDR-III) sequence analysis in childhood B-lineage acute lymphoblastic leukemia: implications for the design of oligonucleotides for use in monitoring minimal residual disease. Leukemia, 6, 1213-1219.
41. II-proximal human Ig H chain V region gene, VH6, in the expressed immune repertoire. Journal of Immunology, 150, 4985-4995.
42. Wasserman, R., Galili, N., Ito, Y., Reichard, B.A., Shane, S. & Rovera, G. (1987) Predominance of foetal type DJH joining in young children with B precursor lymphoblastic leukaemia as evidence for an in utero transforming event. Journal of Exprimental Medicine, 176, 1577-1581.
43. Wasserman, R., Ito, Y., Galili, N., Yamada, M., Reichard, B.A., Shane, S., Lange, B. & Rovera, G. (1992a) The pattern of joining (JH) gene usage in the human IgH chain is established predominantly at the precursor cell stage. Journal of Immunology, 149, 511-516.
44. Wasserman, R., Yamada, M., Ito, Y., Finger, R.L., Reichard, A.B., Shane, S., Lange, B. & Rovera, G. (1992b) VH gene rearrangement events can modify the immunoglobulin heavy chain during progression of B-lineage acute lymphoblastic leukemia. Blood, 79, 223-228.
45. Yamada, M., Wasserman, R., Reichard, B.A., Shane, S., Caton, A.J. & Rovera, G. (1991) Preferential utilisation of specific immunoglobulin heavy chain diversity and joining segments in adult human peripheral blood B lymphocytes. Journal of Experimental Medicine, 173, 395-407.