Bone marrow and renal injury associated with haloalkene cysteine conjugate in calves

Archives of Toxicology

Volumn 70, Issue 10, 1996, Pages 607-619

  Lock, Edward A ^a   Sani, Yulvian ^b   Moore, Richard B ^a   Finkelstein, Martin B ^c   Anders, M W ^c   Seawright, Alan A ^b  

^a ASTRAZENECA   (United Kingdom)

^b UNIVERSITY OF QUEENSLAND   (Australia)

^c UNIVERSITY OF ROCHESTER   (United States)

Author keywords

(1,1,2,2 Tetrafluoroethyl) L cysteine; Aplastic anaemia; Calves; Hexachloro 1,3 butadiene; N Acetyl S (1,2,3,4,4 pentachloro 1,3 butadienyl) L cysteine; N Acetyl S (1,2 dichlorovinyl) L cysteine; Renal injury; S (1,1,2 Trichlorovinyl) L cysteine; S (1,2,3,4,4 Pentachloro 1,3 butadienyl) L cysteine; S (1,2 Dichlorovinyl) DL methylcysteine; S (1,2 Dichlorovinyl) L cysteine

Indexed keywords

CYSTEINE CONJUGATE; HALOOLEFIN; HEXACHLOROBUTADIENE; S (1,2 DICHLOROVINYL)CYSTEINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APLASTIC ANEMIA; ARTICLE; CATTLE; CONTROLLED STUDY; FEMALE; KIDNEY INJURY; MALE; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; BONE MARROW; BUTADIENES; CATTLE; CYSTEINE; FEMALE; FUNGICIDES, INDUSTRIAL; HYDROCARBONS, HALOGENATED; KIDNEY; MALE;

ANIMALIA; BOS TAURUS;

EID: 0029737345     PISSN: 03405761     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002040050319     Document Type: Article

References (38)

1. Anders M W, Elfarra AA, Lash LH (1987) Cellular effects of reactive intermediates: nephrotoxicily of S-conjugates of amino acids. Arch Toxicol 60: 103-108
2. Anderson PM, Schnltze MO (1965) Cleavage of S-(1,2-dichlorovinyl)-L-cysteine by an enzyme of bovine origin. Arch Biochem Biophys III: 593-602
3. Bhattacharya RK, Schultze MO (1967) Enzyme from bovine and turkey kidneys which cleave S-(1,2-dichlorovinyl)-L-cysteine. Comp Biochem Physiol 22: 723-735
4. Bhattacharya RK, Schultze MO (1971a) Properties of DNA isolated from tissues of calves treated with S-(1.2-dichlorovinyl)-L-cysteinc. 1. Chemical and physical properties. Arch Biochem Biophys 145: 565 574
5. Bhattacharya RK, Schultze MO (1971b) Properties of DNA isolated from tissues of calves treated with S-(1,2-dichlorovinyl)-L-cysteine. 2. Primer-template activity for bacterial DNA polymerase. Arch Biochem Biophys 145: 575-582
6. Bhattacharya RK, Schultze MO (1972) Properties of DNA treated with S-(1,2-dichlorovinyl)-L-cysteine and a lyase. Arch Biochem Biophys 158: 105 115
7. Bhattacharya RK, Schultze MO (1974) Action of a metabolite of S-(1,2-dichlorovinyl)-L-cysteineon poly-L-lysine, poly-L-arginine, and their soluble DNA complexes. Arch Biochem Biophys 161: 40-45
8. Commandeur JNM, Stijntjes GJ, Wijngaard J, Vermeulen NPE (1991) Metabolism of L-cysteine S-conjugates and N-(trideuteroacetyl)-L-cysteine S-conjugates of four fluoroethylenes in the rat. Role of balance of deacetylation and acetylation in relation to the nephrotoxicity of mercapturic acids. Biochem Pharmacol 42: 31-38
9. Dekant W, Anders MW, Monks TJ (1993) Bioactivation of halogenated xenobiotics by S-conjugate formation. In: Anders MW, Dekant W, Henschler D, Oberleithner H. Silbernagl S (eds) Renal disposition and nephrotoxicity of xenobiotics. Academic Press. New York, pp 187-215
10. 35S-(1.2-dichlorovinyl)-L-cysteine in the rat. Biochem Pharmacol 12: 465-474
11. 35S-(dichlorovinyl)-L-cysteine in the calf. Biochem Pharmacol 12: 475-488.
12. Dohn DR, Leininger JR, Lash LH, Ouebbemann AJ, Anders MW (1985) Nephrotoxicity of S-(2-chloro-1,1,2-trifluoroethyl) glutathione and S-(2-chloro-1,1,2-trifluorethyl)-L-cysteine, the glutathione and cysteine conjugates of chlorotrifluoroethene. J Pharmacol Exp ther 235: 851-857
13. Elfarra AA, Jakobson I. Anders MW (1986) Mechanism of S-(1.2-dichlorovinyl)-DL-α-methylcysteine. Biochem Pharmacol 35: 283 - 288
14. 35S]-(1,2-dichlorovinyl)-L-cysteine in the male Fischer 344 rat. Drug Metab Dispos 23: 124-128
15. Ford EJH, Evans J (1985) Distribution of 5′-nucleotidase in the tissue of sheep and the effect of kidney and liver lesions on the activity of the enzymes in plasma and urine. Res Vet Sci 39: 103-109
16. Green T, Odum J (1985) The nephrotoxicity and mutagenicity of cysteine conjugates of haloalkenes. Chem Biol Interact 54: 15-31
17. Harleman JH, Seinen W (1979) Short-term toxicity and reproduction studies in rats with hexachloro-1,3-butadiene. Toxicol Appl Pharmacol 47: 1-14
18. Ishmael J, Lock EA (1986) Nephrotoxicity of hexachlorobutadiene and its glutathione-derived conjugates. Toxicol Pathol 14: 258-262
19. Jones TW, Qin C, Schaeffer VH. Stevens JL (1989) Immunohistochemical localisation of glutamine transaminase K. a rat kidney cysteine conjugate β-lyase, and the relationship, to the segment specificity of cysteine conjugate nephrotoxicity. Mol Pharmacol 34: 621-627
20. Lock EA (1988) Studies on the mechanism of nephrotoxicity and nephrocarcinogenicity of halogenated alkenes. CRC Crit Rev Toxicol 19: 23-42
21. Lock EA, Ishmael J (1979) The acute toxic effects of hexachloro-1.3-butadiene on the rat kidney. Arch Toxicol 43: 47-57
22. Lock EA, Schnellmann RG (1990) The effect of haloalkene cysteine conjugates on rat renal glutathione reductase and lipoyl dehydrogenase activities. Toxicol Appl Pharmacol 104: 180 190
23. Lock EA, Ishmael J, Pratt IS (1982) Hydropic change in rat liver induced by hexachloro-1.3-butadiene. J Appl Toxicol 2: 315 320
24. Lock EA Pratt IS, Ishmael J (1985) Hexachloro-1.3-butadiene induced hydropic change in mouse liver. J Appl Toxicol 5: 74-79
25. Lowry OH, Rosebrough NJ, Farr AL, Randall RJ (1951) Protein measurement with the Folin phenol reagent. J Biol Chem 193: 265-275
26. MacFarlane M, Foster JR, Gibson GG, King LJ, Lock EA (1989) Cysteine conjugate β-lyase of rat kidney eytosol: characterisation, immunocytochemical localisation, and correlation with hexachlorobutadiene nephrotoxicity. Toxicol Appl Pharmacol 98: 185-197
27. McKinney LL, Weakley FB, Eldridge AC, Campbell RE, Cowan JC, Picken Jr JC, Biester HE (1957) S-(1,2-Dichlorovinyl)-L-cysteine: an agent causing fatal aplastic anaemia in calves. J Am Chem Soc 79: 3932-3933
28. McKinney LL, Picken JC, Weakley FB, Eldridge AC, Campbell RE, Cowan JC, Biester HE (1959) Possible toxic factor of trichloroethylene-extracted soybean oil meal. J Am Chem Soc 81:909-915
29. Moore RB, Green T (1988) The synthesis of nephrotoxic conjugates of glutathione and cysteine. Toxicol Environ Chem 17: 153-162
30. Nash JA, King LJ, Lock EA. Green T (1984) The metabolism and disposition of hexachloro-1.3-butadiene in the rat and its relevance to nephrotoxicity. Toxicol Appl Pharmacol 73: 124-137
31. Odum J, Green T (1984) The metabolism and nephrotoxicity of tetrafluoroethylene in the rat. Toxicol Appl Pharmacol 76: 306-318
32. Pratt IS, Lock EA (1988) Deacetylation and further metabolism of the mercapturic acid of hexachloro-1,3-butadiene by rat renal eytosol in vitro. Arch Toxicol 62: 341-345
33. Schultze MO, Klubes P, Perman V, Mizuno NS, Bates FW, Sautter JH (1959) Blood dyscrasia in calves induced by S-(1,2-dichlorovinyl)-cysteine. Blood 14: 1015-1025
34. Seawright AA. Sani Y, Lock EA (1994) Renal injury and haematological changes associated with haloalkene cysteine conjugates in calves. Toxicologist 14: 72 (abstr)
35. Stevens JL, Jakoby WB (1983) Cysteine conjugate βlyase. Mol Pharmacol 23: 761-765
36. Stockman SC (1916) Cases of poisoning in cattle feeding on meal from soya bean after extraction of the oil. J Comp Pathol Ther 29: 95-107
37. Terracini B, Parker VH ( 1965) A pathological study of the toxicity of S-(1,2-dichlorovinyl)-L-cysteine. Food Cosmet Toxicol 3: 67-74
38. Vamvakas S, Dekant W, Berthold K, Schmidt S, Wild D, Henschler D (1988) Enzymatic transformation of mercapturic acids derived from halogenated alkenes to reactive and mutagenic intermediates. Biochem Pharmacol 36: 2741 2748