DL-α-aminoadipate is a toxin to Muller cells

Progress in Retinal and Eye Research

Volumn 15, Issue 2, 1996, Pages 435-456

  Kato, Satoru ^a,c   Mawatari, Kazuhiro ^b   Sugitani, Kayo ^b   Yasui, Yuhko ^a  

^a Department of Neurobiology   (Japan)

^b KANAZAWA UNIVERSITY   (Japan)

^c KANAZAWA UNIV SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

AMINOADIPIC ACID; ANTIPORTER; CYSTINE; EYE PROTEIN; GLIOTOXIN; GLUTAMIC ACID; GLUTATHIONE; OXYGEN RADICAL; REACTIVE OXYGEN METABOLITE;

AMINO ACID TRANSPORT; ANIMAL CELL; CARP; CELL DAMAGE; CELL STRUCTURE; CONTROLLED STUDY; DNA SYNTHESIS; DOSE RESPONSE; ELECTRORETINOGRAM; INTRACELLULAR RECORDING; MUELLER CELL; NERVE CELL; NERVOUS SYSTEM ELECTROPHYSIOLOGY; NEUROTOXICITY; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN SYNTHESIS; RETINA INJURY; REVIEW; STEREOSPECIFICITY;

EID: 0029737026     PISSN: 13509462     EISSN: None     Source Type: Journal    
DOI: 10.1016/1350-9462(96)00010-9     Document Type: Review

References (76)

1. Bannai, S. (1986) Exchange of cystine and glutamate across plasma membrane of human fibroblasts. J. biol. Chem. 261: 2256-2263.
2. Bannai, S. and Kitamura, E. (1980) Transport interaction of L-cystine and L-glutamate in human diploid fibroblasts in culture. J. biol. Chem. 255: 2372-2376.
3. Bonaventure, N., Wioland, N. and Roussel, G. (1985) Stereospecific effects of the α-aminoadipic acid on the retina: a morphological and electrophysiological study. Doc. Ophthal. 61: 71-77.
4. Bonaventure, N., Roussel, G. and Wioland, N. (1981) Effects of D,L-alpha-aminoadipic acid on Müller cells in frog and chicken retina in vivo: relation to ERG b-wave, ganglion cell discharges and tectal evoked potentials. Neurosci. Lett. 27: 81-87.
5. Casper, D. S. and Reif-Lehrer, E. (1983) Effects of alpha-aminoadipate isomers on the morphology of the isolated chick embryo retina. Invest. Ophthal. vis. Sci. 24: 1480-1488.
6. Casper, D. S., Trelstad, R. L. and Reif-Lehrer, L. (1982) Glutamate-induced cellular injury in isolated chick embryo retina: Müller cell localization of initial effects. J. comp. Neurol. 209: 79-90.
7. Cho, Y. and Bannai, S. (1990) Uptake of glutamate and cystine in C6 glioma cells and in cultured astrocytes. J. Neurochem. 55: 2091-2097.
8. Choi, D. W. (1988) Glutamate neurotoxicity and disease of the nervous system. Neuron 1: 623-634.
9. Foster, A. C. and Fagg, G. E. (1984) Acidic amino acid binding sites in mammalian neuronal membranes: their characteristics and relationship to synaptic receptors. Brain Res. Rev. 7: 103-164.
10. Fujimoto, M. and Tomita, T. (1979) Reconstruction of the slow PHI from the rod potential. Invest. Ophthal. vis. Sci. 18: 1090-1093.
11. Garthwaite, J. and Regan, C. M. (1980) Toxic effects of α-aminoadipate on cultured cerebellar cells. Brain Res. 194: 603-607.
12. Griffith, O. W. and Meister, A. (1979) Potent and specific inhibition of glutathione synthesis by buthionin sulfoximine (S-n-butylhomocvsteine sulfoximine). J. biol. Chem. 254: 7558-7560.
13. Grossman, R., Fox. L. E., Gorovits, R., Ben-Droro, I., Reisfeld, S. and Vardimon, L. (1994) Molecular basis for differential expression of glutamine synthetase in retina. Molec. Brain Res. 21: 312-320.
14. Higuchi. Y., Kato, S. and Matsukawa, S. (1994) Involvement of protein kinase C in apoptosis induced by glutamate in C6 rat glioma cells. In: Proc. XVIth Internal. Cancer Cong. (R. S. Rao. M. G. Deo and L. D. Sanghui, eds), pp. 857-861. New Delhi.
15. Huck, S., Grass, F. and Hatten, M. E. (1984) Gliotoxic effects of alpha-aminoadipic acid on monolayer cultures of dissociated postnatal mouse cerebellum. Neuroscience 12: 783-791.
16. Ishida, A. T. and Fain, G. E. (1981) D-Aspartate potentiates the effects of L-glutamate on horizontal cells in goldfish retina. Proc. natn. Acad. Sci. U.S.A. 78: 5890-5894.
17. Ishikawa, Y. and Mine, S. (1982) Structural changes in retinal glial cells following the intravitreal injection of DL-α-aminoadipic acid. J. Jpn. Ophthal. Soc. 86: 100-110.
18. 3H] dopamine release study with isolated cell fractions. J. Neurochem. 50: 1-6.
19. Johns, P. R. and Fernald, R. D. (1981) Genesis of rods in teleost fish retina. Nature 293: 141-142.
20. Kato, S., Higashida, H., Higuchi, Y., Hatakenaka, S. and Negishi, K. (1984) Sensitive and insensitive states of cultured glioma cells to glutamate damage. Brain Res. 303: 365-373.
21. Kato, S., Ishita, S., Sugawara, K. and Mawatari, K. (1993a) Cystine/glutamate antiporter expression in retinal Müller glial cells: Implications for DL-α-aminoadipate toxicity. Neuroscience 57: 473-482.
22. Kato, S., Negishi, K., Honma, K., Sakai, K. and Shimada, Y. (1989) A high performance liquid chromatography assay for glutamine synthetase. Neurochem. Int. 14: 491-496.
23. Kato, S., Negishi, K., Mawatari, K. and Kuo, C. H. (1992) A mechanism for glutamate toxicity in the C6 glioma cells involving inhibition of cystine uptake leading to glutathione depletion. Neuroscience 48: 903-914.
24. Kato, S., Negishi, K., Teranishi, T. and Ishita, S. (1991) The use of the carp retina in neurobiology: its uniqueness and application for neural network analyses of the inner retina. Progr. Neurobiol. 37: 287-327.
25. Kato, S., Shinagawa, S., Sugawara. K., Mawatari, K. and Shimada, Y. (1993b) Glutamate toxicity leading to GSH depletion through the xc̄ antiporter system in the glial cells. In: Proc. Internat. Conf. Peripheral Nerve Toxicity (K. Hashimoto, ed.), pp. 119-121. Kanazawa.
26. Kato, S., Sugawara, K., Matsukawa, T. and Negishi, K. (1990) Gliotoxic effects of α-aminoadipic acid isomers on the carp retina: a long-term observation. Neuroscience 36: 145-153.
27. Kato, S., Teranishi, T. and Negishi, K. (1985) L-Glutamate depolarizes ON-OFF transient type of amacrine cells in the carp retina: an ionophoretic study. Brain Res. 329: 390-394.
28. Kessler, M., Baudry, M. and Lynch, G. (1987) Use of cystine to distinguish glutamate binding from glutamate sequestration. Neurosci. Lett. 81: 221-226.
29. Lebel, C. P. and Bondy, S. C. (1990) Sensitive and rapid quantitation of oxygen reactive species formation in rat synaptosomes. Neurochem. Int. 17: 435-440.
30. Linser, P. J. and Moscona, A. A. (1981) Induction of glutamine synthetase in embryonic neural retina: its suppression by the gliatoxic agent alpha-aminoadipic acid. Brain Res. 227: 103-119.
31. Lucas, D. R. and Newhouse, J. P. (1957) The toxic effect of sodium L-glutamate on the inner layers of the retina. Arch. Ophthal. 58: 193-201.
32. Lund Karlsen, R. (1978) The toxic effect of sodium glutamate and DL-α-aminoadipic acid on rat retina: changes in high affinity uptake of putative neurotransmitters. J. Neurochem. 31: 1055-1061.
33. MacLennan, H. and Hall, J. G. (1978) The action of D-α-aminoadipate on excitatory amino acid receptors of rat thalamic neurons. Brain Res. 149: 541-545.
34. Mangel, S. C., Ariel, M. and Dowling, J. E. (1985) Effects of amino acid antagonists upon the spectral properties of carp horizontal cells: circuitry of the outer retina. J. Neurosci. 5: 2839-2850.
35. Mawatari, K., Yasui, Y., Sugitani, K., Takadera, T. and Kato, S. (1996) Reactive oxygen species involved in the glutamate toxicity of C6 glioma cells via xc̄ antiporter system. Neuroscience 73: 201-208.
36. Meister, A. (1988) Glutathione metabolism and its selective modification. J. biol. Chem. 263: 17205-17208.
37. Meldrum, B. (1993) Amino acids as dietary excitotoxins: a contribution to understanding neurodegenerative disorders. Brain Res. Rev. 18: 293-314.
38. Memo, M., Riccardi, R., Trabucchi, M. and Spano, P. F. (1981) Localization of GABA and dopamine receptor sites in retinal glial cells using DL-α-aminoadipic acid. In: Advances in Biochemical Psychopharmacology (E. Costa, G. D. Chiara and G. L. Gessa. eds) GABA and Benzodiazepine Receptors. Vol. 26. pp. 41-45. Ravan Press, New York.
39. Miller, R. F. and Dowling, J. E. (1970) Intracellular responses of the Müller (glial) cells of mudpuppy retina: their relation to b-wave of the electroretinogram. J. Neurophysiol. 33: 323-341.
40. Murakami, M., Ohtsuka, T. and Shimazaki, H. (1975) Effects of aspartate and glutamate on the bipolar cells in the carp retina. Vision Res. 15: 456-458.
41. Murphy. T. H., Miyamato, M., Sastre, A., Schnaar, R. L. and Coyle, J. T. (1989) Glutamate toxicity in a neuronal cell line involves inhibition of cystine transport leading to oxidative stress. Neuron 2: 1547-1558.
42. Murphy, T. H., Schnaar, R. L. and Coyle, J. T. (1990) Immature cortical neurons are uniquely sensitive to glutamate toxicity by inhibition of cystine uptake. Fedn. Am. Soc. expl Biol. 4: 1624-1633.
43. Negishi, K., Teranishi, T. and Kato, S. (1989) The dopamine system of the teleost fish retina. Progr. Retinal Res. 9: 1-48.
44. Negishi, K., Teranishi, T., Kato, S. and Nakamura, Y. (1987) Paradoxical induction of dopaminergic cells following intravitreal injection of high doses of 6-hydroxydopamine in juvenile carp retina. Derl. Brain Res. 33: 67-79.
45. Newman, E. A. (1979) B-wave currents in the frog retina. Vision Res. 19: 227-234.
46. Oakley, B. III and Green, D. G. (1976) Correlation of light-induced changes in retinal extracellular potassium concentration with c-wave of the electroretinogram. J. Neurophysiol. 39: 1117-1133.
47. Oka, A., Belliveau, M. J., Rosenberg, P. A. and Volpe, J. J. (1993) Vulnerability of oligodendroglia to glutamate: pharmacology, mechanism and prevention. J. Neurosci. 13: 1441-1453.
48. Oliver. C. N., Starke-Reed, P. E., Stadtman, E. R., Liu, G. J., Carnery, J. M. and Floid, R. A. (1990) Oxidative damage to brain proteins, loss of glutamine synthetase activity, and production of free radicals during ischemia/reperfusion-induced injury to gerbil brain. Proc. natn. Acad. Sci. U.S.A. 87: 5144-5147.
49. Olney. J. W., de Gubareff, T. and Collins, J. F. (1980) Stereospecificity of the gliotoxic and anti-neurotoxic actions of alpha-amino adipate. Neurosci. Lett. 19: 277-282.
50. Olney, J. W., Ho, O. L. and Rhee, V. (1971) Cytotoxic effect of acidic and sulphur containing amino acids on the infant mouse central nervous system. Expl Brain Res. 14: 61-76.
51. + -dependent glutamate transport into acutely isolated Müller glial cells from guinea pig retina. Pflügers Arch. Eur. J. Physiol. 429: 140-142.
52. Pearlman, E. M., Siegel, G. M. and Notter, M. F. D. (1993) Induction of c-fos by excitatory amino acids in developing chick retina is affected by changes in cellular interactions. J. Neurosci. Res. 36: 252-259.
53. Pedersen, O. O. and Lund Karlsen, R. (1979) Destruction of Müller cells in the adult rat by intravitreal injection of D,L-α-aminoadipic acid, an electron microscopic study. Expl. Eye Res. 28: 569-575.
54. 3H]-glutamate binding: a new receptor or a particular transport process? Fedn Eur. biochem. Soc. Lett. 175: 31-36.
55. Porciatti, V., Bagnoli, P.. Alesei, R. and Fontanesi, G. (1987) Pharmacological dissociation of the b-wave and pattern electroretinogram. Doc. Ophthal. 65: 377-383.
56. Pow, E. V. and Crook, D. K. (1995) Immunocytochemical evidence for the presence of high levels of reduced glutathione in radial glial cells and horizontal cells in the rabbit retina. Neurosci. Lett. 193: 25-28.
57. Raps, S. P.. Lai, J. C. K., Hertz, L. and Cooper, A. J. L. (1989) Glutathione is present in high concentrations in cultured astrocytes but not in cultured neurons. Brain Res. 493: 398-401.
58. Reichelt, W., Pannicke, T., Francke, M. and Heinemann, U. (1996) Relation between glutamate uptake,cystine/ glutamate antiporter and glutathione synthesis in guinea pig Müller cells. J. Brain Res. 37: 224.
59. Reichenbach, A. and Wohlrab, F. (1985) Effects of α-aminoadipic acid on the glutamate-isolated PHI of the rabbit electroretinogram. Doc. Ophthal. 59: 359-364.
60. Riepe, R. E. and Norenberg. M. D. (1977) Müller cell localization of glutamine synthetase. Nature 268: 654-655.
61. Sagara, J., Miura, K. and Bannai, S. (1993) Maintenance of neuronal glutathione by glial cells. J. Neurochem. 61: 1672-1676.
62. Shinagawa, S. (1994) Serotonin protects C6 glioma cells from glutamate toxicity. Neuroscience 59: 1043-1050.
63. Slater, T. F. (1984) Free radical mechanisms in tissue injury. Biochem. J. 222: 1-15.
64. Sugawara, K., Torigoe, K., Okoyama, S., Negishi, K. and Kato, S. (1990) Neurotoxic effects of L-α-aminoadipic acid on the carp retina: a long term observation. Neuroscience 36: 155-163.
65. Szamier, R. B., Ripps, H. and Chappell, R. L. (1981) Changes in ERG b-wave and Müller cell structure induced by alpha-aminoadipic acid. Neurosci. Lett. 21: 307-312.
66. Takada, M. and Hattori, T. (1986) Fine structural changes in the rat brain after local injections of gliotoxin, alpha-aminoadipic acid. Histol. Histopath. 1: 271-275.
67. Toyooka, T., Uchiyama, S., Saito, Y. and Imai, K. (1988) Simultaneous determination of thiols and disulfides by high-performance liquid chromatography with fluorescence detection. Analyt. Chim. Acta 205: 29-41.
68. Wachtmeister, L. (1981) Further studies of the chemical sensitivity of the oscillatory potentials of the electroretinogram (ERG). I. Glutamate - aspartate and dopamine antagonists. Acta Ophthal. 59: 247-258.
69. 2+ concentration caused by aminoadipic acid enantiomers in retinal Müller cells and neurons in vitro. Doc. Ophthal. 80: 385-395.
70. Welinder, E., Textorius, D. and Nilsson, S. E. G. (1982) Effects of intravitreally injected DL-α-aminoadipic acid on the c-wave of the d.c.-recorded electroretinogram in albino rabbits. Invest. Ophthal. vis. Sci. 23: 240-245.
71. Werling, L. L. and Nadler, J. V. (1983) L-Glutamate binding to hippocampal synaptic membranes: two binding sites discriminating by their differing affinities for quisqualate. J. Neurochem. 41: 586-593.
72. Wu, S. M. and Dowling, J. E. (1978) L-Aspartate: evidence for a role in cone photoreceptor synaptic transmission in the carp retina. Proc. natn. Acad. Sci. U.S.A. 75: 5205-5209.
73. Yasui, Y., Mawatari, K., Higuchi, Y., Tanii, H. and Kato, S. (1996) Involvement of oxygen radicals in the glutamate toxicity of C6 glioma cells via transporter system. In: Free Radicals in Brain Physiology and Disorders (L. Packer, M. Hiramatsu and T. Yoshikawa, eds). Academic Press, New York, in press.
74. 15N]glutamate. J. Neurochem. 55: 137-145.
75. Zaczek, R., Balm, M., Arlis, S., Drucker, H. and Coyle, J. T. (1987) Quisqualate-sensitive, chloride-dependent transport of glutamate into rat brain synaptosomes. J. Neurosci. Res. 18: 425-431.
76. Zimmerman, R. P. and Corfman, T. P. (1984) A comparison of the effects of isomers of alpha-aminoadipic acid and 2-amino-4-phosphonobutyric acid on the light response of the Müller glial cell and the electroretinogram. Neuroscience 12: 77-84.