Effects of glucose, forskolin and tolbutamide on membrane potential and insulin secretion in the insulin secreting cell line INS-1

Pflugers Archiv European Journal of Physiology

Volumn 432, Issue 4, 1996, Pages 630-636

  Ullrich, Susanne ^a   Abel, Kirsten Berit ^a   Lehr, Sabine ^a   Greger, Rainer ^a  

^a UNIVERSITY OF FREIBURG   (Germany)

Author keywords

Glucose induced action potentials; INS 1 cells; Insulin secretion; Insulin secreting cell line; Membrane voltage; Patch clamp analysis; Sulphonylurea

Indexed keywords

FORSKOLIN; GLUCOSE; INSULIN; SULFONYLUREA DERIVATIVE; TOLBUTAMIDE;

ACTION POTENTIAL; ARTICLE; CELL MEMBRANE DEPOLARIZATION; CELL MEMBRANE POTENTIAL; CONCENTRATION RESPONSE; HUMAN; HUMAN CELL; INSULIN RELEASE; INSULINOMA; PATCH CLAMP; PRIORITY JOURNAL;

ACTION POTENTIALS; ANIMALS; CELL LINE; DOSE-RESPONSE RELATIONSHIP, DRUG; FORSKOLIN; GLUCOSE; INSULIN; ISLETS OF LANGERHANS; MEMBRANE POTENTIALS; RATS; TOLBUTAMIDE;

EID: 0029736855     PISSN: 00316768     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004240050179     Document Type: Article

References (29)

1. ATPchannels is not involved. Pflügers Arch 432:89-96
2. Aguilar-Bryan L, Nichols CG, Wechsler SW, Clement JP IV, Boyd AE III, González G, Herrera-Sosa H, Nguy K, Bryan J, Nelson DA (1995) Cloning of the β cell high-affinity sulfonylurea receptor: a regulator of insulin secretion. Science 268:423-426
3. Asfari M, Janjic D, Meda P, Li G, Halban PA, Wollheim CB (1992) Establishment of 2-mercaptoethanol-dependent differentiated insulin-secreting cell lines. Endocrinology 130:167-178
4. Asheroft FM, Rorsman P (1989) Electrophysiology of the pancreatic β-cell. Prog Biophys Mol Biol 54:87-143
5. Ashcroft SJH, Ashcroft FM (1990) Properties and functions of ATP-sensitive K-channels. Cell Signal 2:197-214
6. 2+ channels and insulin-containing secretory granules and its significance for the initiation of exocytosis in mouse pancreatic B-cells. EMBO J 14:50-57
7. +-channels in pancreatic β-cells. Nature 311:269-271
8. +-channels in pancreatic β-cells. Spare channel hypothesis. Diabetes 37:495-498
9. Detimary P, Gilon P, Nenquin M, Henquin JC (1994) Two sites of glucose control of insulin secretion with distinct dependence on the energy stale in pancreatic β-cells. Biochem J 297:455-461
10. 2+ currents in pancreatic islet B cells. FEBS Lett 251:167-172
11. +-channels in mouse B cells. J Clin Invest 91:871-880
12. + channels in the basolateral membrane of rabbit proximal straight tubules. Pflügers Arch 410:288-295
13. 29 colon carcinoma and CF-PAC cells. Pflügers Arch 419:209-211
14. Henquin JC, Meissner HP (1984) Significance of ionic fluxes and changes in membrane potential for stimulus-secretion coupling in pancreatic β-cells. Experientia 40:1043-1052
15. Herbert V, Lau KS, Gottlieb CW, Bleicher SJ (1965) Coated charcoal immunoassay of insulin. J Clin Endocrinol Metab 25:1375-1384
16. Ishihara H, Asano T, Tsukuda K, Katagiri H, Inukai K, Anai M, Kikuchi M, Yazaki Y, Miyazaki JI, Oka Y (1993) Pancreatic beta cell line MIN6 exhibits characteristics of glucose metabolism and glucose-stimulated insulin secretion similar to those of normal islets. Diabetologia 36:1139-1145
17. m glucose transporter of islets of Langerhans is functionally similar to the low affinity transporter of liver and has an identical primary sequence. J Biol Chem 265:6548-6551
18. 29 colonic carcinoma cells. Pflügers Arch 430:253-265
19. Pipeleers DG, Schuit FC, In'T Velt PA, Maes E, Hooghe-Peters EL, Van De Winkel M, Gepts W (1985) Interplay of nutrients and hormones in the regulation of insulin release. Endocrinology 117:824-833
20. Praz GA, Halban PA, Wollheim CB, Blondel B, Strauss AJ, Renold AE (1983) Regulation of immunoreactive-insulin release from a rat cell line (RINm5F). Biochem J 210:345-352
21. 2+, cAMP and phospholipid-derived messengers in coupling mechanisms of insulin secretion. Physiol Rev 67:1185-1249
22. +-channel in insulin-secreting cells. J Biol Chem 262:15840-15844
23. + currents in isolated mouse pancreatic β-cells. FEBS Lett 261:187-190
24. + channels is impaired in beta-cells of GK rat. A new genetic model of NIDDM. Diabetes 42:1446-1453
25. Unger RH (1991) Diabetic hyperglycemia: link to impaired glucose transport in pancreatic β-cells. Science 251:1200-1205
26. 2-adrenergic inhibition of insulin release. Studies with epinephrine and forskolin. J Biol Chem 259:4111-4115
27. 2+-induced insulin secretion in permeabilized HIT-T15 cells. Biochem J: 270:273-276
28. Wang JL, Corbell JA, Marshall CA, McDaniel ML (1993) Glucose-induced insulin secretion from purified β-cells. J Biol Chem 268:7785-7791
29. +-channels in pancreatic β-cells is not mediated by cAMP. Pflügers Arch 411:613-619