Multiple gene expression in baculovirus system. Third generation vaccines for bluetongue disease and African horsesickness disease

Annals of the New York Academy of Sciences

Volumn 791, Issue , 1996, Pages 318-332

  Roy, Polly ^a,b,c  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^c NATURAL ENVIRONMENT RESEARCH COUNCIL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CAPSID PROTEIN; CORE PROTEIN; NEUTRALIZING ANTIBODY; VACCINE;

AFRICAN HORSE SICKNESS VIRUS; ANIMAL EXPERIMENT; ANIMAL MODEL; BACULOVIRUS; BLUETONGUE ORBIVIRUS; CONFERENCE PAPER; CONTROLLED STUDY; GENE EXPRESSION; HORSE DISEASE; IMMUNOGENICITY; NONHUMAN; ORBIVIRUS; PROTEIN SYNTHESIS; SHEEP DISEASE; SUBCUTANEOUS DRUG ADMINISTRATION; VACCINE PRODUCTION; VIRUS INFECTION; VIRUS PARTICLE;

EID: 0029736837     PISSN: 00778923     EISSN: None     Source Type: Book Series    
DOI: 10.1111/j.1749-6632.1996.tb53539.x     Document Type: Conference Paper

References (19)

1. ROY, P. & B. M. GORMAN. 1990. Bluetongue viruses. In Current Topics in Microbiology and Immunology. P. Roy & B. M. Gorman, Eds.: 1-200. Springer-Verlag. Heidelberg, Germany.
2. PRASAD, B. V. V., S. YAMAGUCHI & P. ROY. 1992. Three-dimensional structure of single-shelled BTV. J. Virol. 66: 2135-2142.
3. HEWAT, E. A., T. F. BOOTH, P. T. LOUDON & P. ROY. 1992. 3-D reconstruction of bluetongue virus core-like particles by cryo-electron microscopy. Virology 189: 10-20.
4. HEWAT, E. A., T. F. BOOTH & P. ROY. 1992. Structure of bluetongue virus particle by cryo-electron microscopy. J. Struct. Biol. 109: 61-69.
5. BISHOP, D. H. L. 1992. Baculovirus expression vectors. Semin. in Virol. 3: 253-264.
6. O'REILLY, D. R., L. K. MILLER & V. A. LUCKOW. 1992. In Baculovirus Expression Vectors: A Laboratory Manual. W. H. Freeman and Company.
7. ROY, P. 1992. Bluetongue virus proteins. (Review article.) J. Gen. Virol. 73: 3051-3064.
8. ROY, P., P. P. C. MERTENS & I. CASAL. 1994. African horsesickness virus structure. (Review article.) In Comparative Immunology Microbiology and Infectious Diseases. 17 (3/4): 243-273. Elsevier Science Ltd. Cambridge, United Kingdom.
9. FRENCH, T. J. & P. ROY. 1990. Synthesis of bluetongue virus (BTV) core-like particles by a recombinant baculovirus expressing the two major structural core proteins of BTV. J. Virol. 64: 1530-1536.
10. GRIMES, J., A. BASAK, P. ROY & D. I. STUART. 1995. The crystal structure of bluetongue virus VP7; implications for virus assembly. Nature 373: 167-170.
11. FRENCH, T. J., J. J. A. MARSHALL & P. ROY. 1990. Assembly of double-shelled, virus-like particles of bluetongue virus by the simultaneous expression of four structural proteins. J. Virol. 64: 5695-5700.
12. BELYAEV, A. S. & P. ROY. 1993. Development of baculovirus triple and quadruple expression vectors: co-expression of three or four bluetongue virus proteins and the synthesis of bluetongue virus-like particles in insect cells. Nucleic Acids Res. 21: 1219-1223.
13. ROY, P., T. J. FRENCH & B. J. ERASMUS. 1992. Protective efficacy of virus-like particles for bluetongue disease. Vaccine 10: 28-32.
14. ROY, P., D. H. L. BISHOP, H. LEBLOIS, S. OLDFIELD & B. J. ERASMUS. 1994. Long-lasting protection of sheep against bluetongue challenge after vaccination with virus-like particles: evidence for homologous and partial heterologous protection. Vaccine 12: 805-811.
15. ROY, P., J. CALLIS & B. J. ERASMUS. 1994. Protection of sheep against bluetongue disease after vaccination with core-like and virus-like particles: Evidence for homologous and partial heterologous protection. In Proceedings for 97th Annual Meeting, USA Health Association: 88-97.
16. ROY, P., T. URAKAWA, A. A. VAN DUK & B. J. ERASMUS. 1990. Recombinant virus vaccine for bluetongue disease in sheep. J. Virol. 64: 1998-2003.
17. MARTINEZ-TORRECUADRADA, J., H. IWATA, A. VENTEO, I. CASAL & P. ROY. 1994. Expression and characterization of the two outer capsid proteins of African horse sickness virus. The role of VP2 in virus neutralization. Virology 202: 348-359.
18. CHUMA, T. H. LE BLOIS, J. M. SANCHEZ-VIZCAINO, M. DIAZ-LAVIADA & P. ROY. 1992. Expression of the major core antigen VP7 of African horse sickness virus by a recombinant baculovirus and its use as a group-specific diagnostic reagent. J. Gen. Virol. 73: 925-931.
19. IWATA, H., T. CHUMA & P. ROY. 1992. Characterization of genes encoding two of the major capsid proteins of epizootic haemorrhagic disease virus indicates a close genetic relationship to bluetongue virus. J. Gen. Virol. 73: 915-924.