CAMP activation of phosphoenol pyruvate carboxykinase transcription in renal LLC-PK1-F+ cells

American Journal of Physiology

Volumn 271, Issue 2 PART 2, 1996, Pages

  Liu, Xiangdong ^a   Curthoys, Norman P ^a  

^a Veterinary Dentistry and Oral Surgery   (United States)

Author keywords

Ccaat enhancer binding protein; Chloramphenicol acetyltransferase; Proximal tubule; Transcription

Indexed keywords

CYCLIC AMP; OKADAIC ACID; PHOSPHOENOLPYRUVATE CARBOXYKINASE (GTP); PHOSPHOPROTEIN PHOSPHATASE; TRANSCRIPTION FACTOR;

ANIMAL CELL; ARTICLE; ENHANCER REGION; ENZYME INHIBITION; ENZYME REGULATION; GENETIC TRANSCRIPTION; GLUCONEOGENESIS; GLUCOSE BLOOD LEVEL; KIDNEY EPITHELIUM; NEPHROLOGY; NONHUMAN; PRIORITY JOURNAL; PROTEIN SYNTHESIS REGULATION; RAT; TRANSCRIPTION REGULATION;

ANIMALS; CHLORAMPHENICOL O-ACETYLTRANSFERASE; CYCLIC AMP; ENHANCER ELEMENTS (GENETICS); KIDNEY; LLC-PK1 CELLS; PHOSPHOENOLPYRUVATE CARBOXYKINASE (GTP); RNA, MESSENGER; SWINE; THIONUCLEOTIDES; TRANSCRIPTION, GENETIC; TRANSFECTION;

EID: 0029736828     PISSN: 00029513     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajprenal.1996.271.2.f347     Document Type: Article

References (31)

1. Brosnan, J. T., P. Vinay, A. Gougoux, and M. L. Halperin. Renal ammonia production and its implications for acid-base balance. In: pH Homeostasis: Mechanism and Control, edited by D. Häussinger. New York: Academic, 1988, p. 281-304.
2. Burch, H. B., C. Narins, C. Chu, S. Fagiolo, S. Choi, W. McCarthy, and O. H. Lowry. Distribution along the rat nephron of three enzymes of gluconeogenesis in acidosis and starvation. Am. J. Physiol. 235(Renal Fluid Electrolyte Physiol. 4): F246-F253, 1978.
3. Chobanian, M. C., and C. M. Julin. Angiotensin II stimulates ammoniagenesis in canine renal proximal tubule segments. Am. J. Physiol. 260(Renal Fluid Electrolyte Physiol. 29): F19-F26, 1991.
4. Chomczynski, P., and N. Sacchi. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 162: 156-159, 1987.
5. Friedlander, G., and C. Amul. Cellular mode of action of parathyroid hormone. Adv. Nephrol. Necker Hosp. 23: 265-279, 1994.
6. German, C. M., L. F. Moffat, and B. H. Howard. Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells. Mol. Cell. Biol. 2: 1044-1051, 1982.
7. Gstraunthaler, G., and J. S. Handler. Isolation, growth and characterization of a gluconeogenic strain of renal cells. Am. J. Physiol. 252(Cell Physiol. 21): C232-C238, 1987.
8. 1 cells during adaptation to glucose-free culture conditions. Renal Physiol. Biochem. 13: 137-153, 1990.
9. Hansen, W. R., L. Taylor, and N. P. Curthoys. The 3′-nontranslated region of rat renal glutaminase mRNA contains a pH-responsive stability element. Am. J. Physiol. 271(Renal Fluid Electrolyte Physiol. 40): F126-F131, 1996.
10. Hanson, R. W., and Y. M. Patel. Phosphoenolpyruvate carboxykinase(GTP): the gene and the enzyme. Adv. Enzymol. Relat. Areas Mol. Biol. 69: 203-281, 1995.
11. Hardie, D. G., T. A. J. Haystead, and A. T. R. Sim. Use of okadaic acid to inhibit protein phosphatases in intact cells. Methods Enzymol. 201: 469-476, 1991.
12. Harris, P. J. Regulation of proximal tubule function by angiotensin. Clin. Exp. Pharmacol. Physiol. 19: 213-222, 1992.
13. + cells. Am. J. Physiol. 271(Renal Fluid Electrolyte Physiol. 40): F340-F346, 1996.
14. Hwang, J.-J., and N. P. Curthoys. Effect of acute alterations in acid-base balance on rat renal glutaminase and phosphoenolpyruvate carboxykinase gene expression. J. Biol. Chem. 266: 9392-9396, 1991.
15. Krylov, D., M. Olive, and C. Vinson. Extending dimerization interfaces: the bZIP basic region can form a coiled coil. EMBO J. 14: 5329-5337, 1995.
16. Kwok, R. P. S., J. R. Lundblad, J. C. Chrivia, J. P. Richards, H. P. Bachinger, S. G. E. Roberts, M. R. Green, and R. H. Goodman. Nuclear protein CBP is a co-activator for the transcription factor CREB. Nature Land. 370: 223-226, 1994.
17. Liu, J., E. A. Park, A. L. Gurney, W. J. Roesler, and R. W. Hansou. Cyclic AMP induction of phosphoenolpyruvate carboxykinase(GTP) gene transcription is mediated by multiple promoter elements. J. Biol. Chem. 266: 19095-19102, 1991.
18. Liu, J., W. J. Roesler, and R. W. Hanson. An efficient method for introducing block mutations into specific regions of a gene. Biotechniques 9: 738-742, 1990.
19. McKnight, S. L., M. D. Lane, and S. Gluecksohn-Waelsch. Is C/EBP a central regulator of energy metabolism? Genes Dev. 3: 2012-2014, 1990.
20. Patel, Y. M., J. S. Yun, J. Liu, M. M. McGrane, and R. W. Hanson. An analysis of the regulatory elements in the phosphoenolpyruvate carboxykinase(GTP) gene which are responsible for its tissue specific expression and metabolic control in transgenic mice. J. Biol. Chem. 269: 5619-5628. 1994.
21. 1 cells. J. Biol. Chem. 270: 20536-20542, 1995.
22. + cells. Am. J. Physiol. 269(Renal Fluid Electrolyte Physiol. 38): F363-F373, 1995.
23. Rasmussen, H., and N. Nagata. Renal gluconeogenesis: effects of parathyroid hormone and dibutyryl cAMP. Biochim. Biophys. Acta 215: 17-28, 1970.
24. Roesler, W. J., J. G. Graham, R. Kolen, D. J. Klemm, and P. J. McFie. The cAMP response element binding protein synergizes with other transcription factors to mediate cAMP responsiveness. J. Biol. Chem. 270: 8225-8232, 1995.
25. Roesler, W. J., G. R. Vanderbark, and R. W. Hanson. Cyclic AMP and the induction of eukaryotic gene transcription. J. Biol. Chem. 263: 9063-9066, 1988.
26. Roesler, W. J., G. R. Vanderbark, and R. W. Hanson. Identification of multiple protein binding domains in the promoter-regulatory region of the phosphoenolpyruvate carboxykinase(GTP) gene. J. Biol. Chem. 264: 9657-9664, 1989.
27. Sachs, A. B. Messenger RNA degradation in eukaryotes. Cell 74: 413-421, 1993.
28. Short, J. M., A. Wynshaw-Boris, H. P. Short, and R. W. Hanson. Characterization of the phosphoenolpyruvate carboxykinase(GTP) promoter-regulatory region. II. Identification of cAMP and glucocorticoid regulatory domains. J. Biol. Chem. 261: 9721-9726, 1986.
29. Tannen, R. L. Renal ammonia production and excretion. In: Handbook of Physiology. Renal Physiology. Bethesda, MD: Am. Physiol. Soc., 1993, sect. 8, vol. I, chapt. 23, p. 1017-1059.
30. Wadzinski, B. E., W. H. Wheat, S. Jaspers, L. F. Peruski, Jr., R. L. Lickteig, G. L. Johnson, and D. J. Klemm. Nuclear protein phosphatase 2A dephosphorylates protein kinase A-phosphorylated CREB and regulates CREB transcriptional stimulation. Mol. Cell. Biol. 13: 2822-2834, 1993.
31. Walton, K. M., R. P. Rehfuss, J. C. Chrivia, J. E. Lochner, and R. H. Goodman. A dominant represser of cyclic adenosine 3′-5′-monophosphate(cAMP)-regulated enhancer binding protein activity inhibits the cAMP-mediated induction of the somatostatin gene in vivo. Mol. Endocrinol. 6: 647-655,1992.