A live (ΔaroA) Aeromonas salmonicida vaccine for furunculosis preferentially stimulates T-cell responses relative to B-cell responses in rainbow trout (Oncorhynchus mykiss)

Infection and Immunity

Volumn 64, Issue 9, 1996, Pages 3863-3869

  Marsden, Matthew J ^a   Vaughan, Laurence M ^b   Foster, Timothy J ^b   Secombes, Christopher J ^a  

^a UNIVERSITY OF ABERDEEN   (United Kingdom)

^b TRINITY COLLEGE DUBLIN   (Ireland)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL VACCINE; LIVE VACCINE;

AEROMONAS SALMONICIDA; ANIMAL EXPERIMENT; ARTICLE; B LYMPHOCYTE; CONTROLLED STUDY; FISH DISEASE; FURUNCULOSIS; INFECTION PREVENTION; NONHUMAN; PRIORITY JOURNAL; RAINBOW TROUT; T LYMPHOCYTE; VACCINATION;

EID: 0029736422     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/iai.64.9.3863-3869.1996     Document Type: Article

References (19)

1. Brown, F., G. Dougan, E. M. Hoey, S. J. Martin, B. K. Rima, and A. Trudgett. 1993. Vaccine design, p. 130. Wiley, Chichester, England.
2. Clem, L. W., N. W. Miller, and J. E. Bly. 1991. Evolution of lymphocyte subpopulations, their interactions and temperature sensitivities, p. 191-213. In G. W. Warr and N. Cohen (ed.), Phylogenesis of immune functions. CRC Press, Boca Raton, Fla.
3. Ellis, A. E., A. S. Burrows, and K. J. Stapleton. 1988. Lack of relationship between virulence of Aeromonas salmonicida and the putative virulence factors: A-layer, extracellular proteases and extracellular haemolysins. J. Fish Dis. 11309-323.
4. Evenden, A. J., T. H. Grayson, M. L. Gilpin, and C. B. Munn. 1993. Reni-bacterium salmoninarum and bacterial kidney disease - the unfinished jigsaw. Annu. Rev. Fish Dis. 387-104.
5. Garduno, R. A., J. C. Thornton, and W. W. Kay. 1993. Fate of the fish pathogen Aeromonas salmonicida in the peritoneal cavity of rainbow trout. Can. J. Microbiol. 391051-1058.
6. Graham, S., and C. J. Secombes. 1990. Cellular requirements for lymphokine secretion by rainbow trout Salmo gairdneri leucocytes. Dev. Comp. Immunol. 1459-68.
7. Izhar, M., L. DeSilva, H. S. Joysey, and C. E. Hormaeche 1990. Moderate immunodeficiency does not increase susceptibility to Salmonella typhimurium aroA live vaccines in mice. Infect. Immun. 582258-2261.
8. Kaattari, S. L. 1992. Fish B lymphocytes: defining their form and function. Annu. Rev. Fish Dis. 2161-180.
9. Kaufmann, S. H. E. 1995. Immunity to intracellular microbial pathogens. Immunol. Today 16338-342.
10. Marsden, M. J., D. Cox, and C. J. Secombes. 1994. Antigen-induced release of macrophage activating factor from rainbow trout Oncorhynchus mykiss leucocytes. Vet. Immunol. Immunopathol. 42199-208.
11. Marsden, M. J., A. DeVoy, L. Vaughan, T. J. Foster, and C. J. Secombes. 1996. Use of a genetically attenuated strain of Aeromonas salmonicida to vaccinate salmonid fish. Aquacult. Int. 455-56.
12. Marsden, M. J., S. H. Hamdani, and C. J. Secombes. 1995. Proliferative responses of rainbow trout, Oncorhynchus mykiss, T and B cells to antigens of Aeromonas salmonicida. Fish Shellfish Immunol. 5199-210.
13. Norqvist, A., A. Bergman, G. Skogman, and H. Wolf-Watz. 1994. A field trial with the live attenuated fish vaccine strain Vibrio anguillarum VAN1000. Bull. Eur. Assoc. Fish Pathol. 14156-158.
14. Sambrook, J., E. F. Fritsch, and T. Maniatis. 1989. Molecular cloning: a laboratory manual, 2nd ed. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.
15. Simon, R., U. Priefer, and A. Puhler. 1983. A broad host range mobilization system for in vivo genetic engineering: transposon mutagenesis in gram negative bacteria. Bio/Technology 1784-791.
16. Thatte, J., S. Rath, and V. Bal. 1993. Immunization with live versus killed Salmonella typhimurium leads to the generation of an IFN-γ-dominant versus an IL-4-dominant immune response. Int. Immunol. 51431-1436.
17. Thompson, L., T. C. Fletcher, D. F. Houlihan, and C. J. Secombes. 1994. The effect of dietary vitamin A on the immunocompetence of Atlantic salmon (Salmo salar L). Fish Physiol. Biochem. 12513-523.
18. Thornton, J. C., R. A. Garduno, S. G. Newman, and W. W. Kay. 1991. Surface disorganised, attenuated mutants of Aeromonas salmonicida as furunculosis vaccines. Microb. Pathog. 1185-89.
19. Vaughan, L. M., P. R. Smith, and T. J. Foster. 1993. An aromatic-dependent mutant of the fish pathogen Aeromonas salmonicida is attenuated in fish and is effective as a live vaccine against the salmonid disease furunculosis. Infect. Immun. 612172-2181.