Induction of p21 mediated by reactive oxygen species formed during the metabolism of aziridinylbenzoquinones by HCT116 cells

Journal of Biological Chemistry

Volumn 271, Issue 50, 1996, Pages 31915-31921

  Qiu, Xiaobo ^a   Forman, Henry Jay ^a   Schönthal, Axel H ^b   Cadenas, Enrique ^a,b  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^b UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2,5 BIS(CARBOETHOXYAMINO) 3,6 DIAZIRIDINYL 1,4 BENZOQUINONE; 2,5 DIAZIRIDINYL 3,6 BIS(2 HYDROXYETHYLAMINO) 1,4 BENZOQUINONE; 3,6 DIAZIRIDINYL 1,4 BENZOQUINONE; ACETYLCYSTEINE; AZIRIDINYLBENZOQUINONE DERIVATIVE; CATALASE; DICOUMAROL; HYDROGEN PEROXIDE; MESSENGER RNA; OXYGEN RADICAL; PROTAMINE KINASE; PROTEIN P21; PROTEIN P53; REACTIVE OXYGEN METABOLITE; SUPEROXIDE DISMUTASE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; COLON CARCINOMA; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG METABOLISM; ELECTRON SPIN RESONANCE; HUMAN; HUMAN CELL; NORTHERN BLOTTING; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INDUCTION;

ACETYLCYSTEINE; ALANINE; ANTINEOPLASTIC AGENTS; AZIRIDINES; BENZOQUINONES; CELL DIVISION; CYCLIN-DEPENDENT KINASE INHIBITOR P21; CYCLINS; DICUMAROL; ENZYME INHIBITORS; FREE RADICALS; HUMANS; HYDROGEN PEROXIDE; NADP; OXIDATION-REDUCTION; OXYGEN; TUMOR CELLS, CULTURED;

EID: 0029730636     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.271.50.31915     Document Type: Article

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