Inhibition of rat parotid gland growth response induced by chronic isoproterenol following treatment with quinolone antibiotics

Molecular and Cellular Biochemistry

Volumn 165, Issue 1, 1996, Pages 55-63

  Kelentey, Barna ^a   Kerr, Micah ^b   Tao, Zeng ^b   Purushotham, Karnam R ^b   Humphreys Beher, Michael G ^b   Zelles, Tivadar ^c  

^a UNIVERSITY OF DEBRECEN   (Hungary)

^b UNIVERSITY OF FLORIDA   (United States)

^c SEMMELWEIS UNIVERSITY   (Hungary)

Author keywords

Antibiotics; Cell proliferation; Salivary glands; Secretion

Indexed keywords

AMYLASE; ISOPRENALINE; MESSENGER RNA; PEFLOXACIN; QUINOLINE DERIVED ANTIINFECTIVE AGENT;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DNA SYNTHESIS; NONHUMAN; PAROTID GLAND; RAT;

ANIMALIA;

EID: 0029730223     PISSN: 03008177     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF00229745     Document Type: Article

References (35)

1. Wang JC: Interactions between DNAs and enzymes. The effect of superhelical turns. J Molec Biol 24: 87-94, 1974
2. Wang, JC: DNA topoisomerases. Ann Rev Biochem 54: 665-697, 1985
3. Hooper DC: Quinolone mode of action-new aspects. Drugs 45: (Suppl. 3): 8-14, 1993
4. Andriole VT: The future of quinolones. Drugs 45 (Suppl. 3): 1-7, 1993
5. Robinson MJ, Martin BA, Gootz TD, McGuirk PR, Osheroff N: Effects of novel fluoroquinolones on the catalytic activities of eukaryotic topoisomerase II: Influence of C-8 fluorine group. Antimicrob Agents Chemother 36: 751-756, 1992
6. Uemora T, Morikawa K, Yanagida M: The nucleotide sequence of the fission yeast DNA topoisomerase II gene: Structural and functional relationships to other DNA topoisomerases. EMBO J 5: 2355-2361, 1986
7. Yamashita Y, Arshizawa T, Morimoto M, Hosomi J, Nakano H: Antitumor quinolones with mammalian topoisomerase II mediated DNA cleavage activity. Cancer Res 52: 2818-2822, 1992
8. Sarkar M, Polk RE, Guzelian PS, Hunt C, Karnes HT: In vitro effect of fluoroquinolones on theophylline metabolism in human liver microsomes. Antimicrob Agents Chemother 34: 594-599 1990
9. Eriksson H, Ridderstrale M, Degerman E, Ekhoim D, Smith CJ, Manganiello VC, Belfrage P, Tomqvist H: Evidence for the key role of the adipose cGMP-inhibited cAMP phosphodiesterase in the antilipolytic action of insulin. Biochim Biophys Acta 1266: 101-107, 1995
10. Endoh M, Satoh H, Norota I, Hirano K, Hosokawa T: Subcellular mechanism of the positive ionotropic effect of a new quinolone derivative OPC-8490 on dog ventricular mycocardium. Heart Vessels 6: 158-167, 1991
11. Purushotham KR, Humphreys-Beher MG: The role of phosphotyrosine signalling pathway in parotid gland proliferation and function. Crit Rev Oral Biol 6: 119-131, 1995
12. Schneyer CA: Salivary gland changes after isoproterenol-induced enlargement. Am J Physiol 203: 232-236, 1962
13. Brown-Grant K: Enlargement of salivary glands in mice treated with isopropyl nor adrenaline. Nature 191: 1076-1078, 1961
14. Schneyer CA: β-adrenergic effects by autonomic agents on mitosis and hypertrophy in rat parotid. Proc Soc Exp Biol Med 131: 71-75, 1969
15. Quissell DO, Watson E, Dowd FJ: Signal transduction mechanisms involved in salivary gland regulated exocytosis. Crit Rev Oral Biol and Med 3: 83-107, 1992
16. Humphreys-Beher MG, Schneyer CA, Kidd VJ, Marchase RB: Isoproterenol-mediated parotid gland hypertrophy is inhibited by effectors of 4β-galactosyltransferase. J Biol Chem 262: 11706-11713, 1987
17. Purushotham KR, Dunn WA Jr, Schneyer CA, Humphreys-Beher MG: A novel mechanism for isoprenaline-stimulated proliferation of rat parotid gland acinar cells involving the EGF-receptor and cell surface galactosyltransferase. Biochem J 284: 767-776, 1992
18. Ciprofloxacin: Product Information Monograph. Compendium of Pre-clinical and Clinical Data. Marcel Dekker Inc, New York 37-45, 1988
19. Bradford M: A rapid and sensitive method for quantitation of microgram quantities of protein using the principle of protein-dye binding. Anal Biochem 72: 248-254, 1976
20. Nakagawa Y, Gammichia J, Purushotham KR, Schneyer CA, Humphreys-Beher MG: Epidermal growth factor activation of rat parotid gland adenylate cyclase and mediation by GTP-binding regulatory protein. Biochem Pharmacol 42: 2333-2340, 1991
21. Gilman AG: A protein binding assay for adenosine 3′:5′ cyclic monophosphate. Proc Natl Acad Sci USA 67: 305-312, 1970
22. Bernfeld P: Amylase, alpha and beta. Meth Enzymol. 1: 149-158, 1955
23. Chomczynski P, Sacchi N: Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem 1162: 156-159, 1987
24. Shing Y, Christofori G, Hanahan D, Ono Y, Sasada R, Igarashi K, Folkman J, Betacellulin: A mitogen from pancreatic β cell tumors. Science 259: 1604-1607, 1993
25. Kerr M, Lee A, Wang PL, Purushotham KR, Chegini N, Yamamoto H, Humphreys Beher MG: Detection of insulin and insulin-like growth factors I and II in saliva and potential synthesis in the salivary glands of mice: Effect of type 1 diabetes mellitus. Biochem Pharmacol 49: 1521-1531, 1995
26. Lee S-W, Purushotham KR, Littlewood T, Evan G, Zelles T, Blazsek J, Nakagawa Y, Humphreys-Beher MG: Down-regulation of cellular proto-oncogenes during inhibition of rat parotid gland acinar cell proliferation. Biochem Biophys Acta 1135: 115-122, 1992
27. Mirels L, Baum B, Kousvelari, E: Dissociation between c-fos gene expression and DNA synthesis in rat parotid glands. Arch Oral Biol 36: 511-515, 1989
28. Kousvelari E, Louis JM, Huang L-H, Curran T: Regulation of protooncogenes in rat parotid cells in vitro after stimulation of β-adrenergic receptors. Exp Cell Res 179: 194-203, 1988
29. Kawano M, Veno A, Ashida Y, Matsumoto N, Inoue H: Effect of sialagogues on ornathine decarboxylase induction and proto-oncogene expression in murine parotid gland. J Dent Res 71: 1885-1890, 1992
30. Kousvelari E, Yeh C-K, Mertz PM, Chinchetra M: Regulation of protooncogenes and salivary gland cell proliferation. Adv Dental Res 4: 61-68, 1990
31. Shaper NL, Harduin-Lepers A, Shaper JH: Male germ cell expression of murine β4-galactosyltransferase. A 796-base pair genomic region, containing two cAMP-responsive element (CRE)-like elements mediates male germ cell-specific expression in transgenic mice. J Biol Chem 269: 25165-25171, 1994
32. Quissel DO, Watson E, Dowd FJ: Signal transduction mechanisms involved in salivary gland regulated exocytosis. Crit Rev Oral Biol Med 3: 83-107, 1992
33. MacKay SLD, Bennett NT, Bland KI, Schultz GS: Growth factors, tumor suppressors, and cancer. Perspectives Gen Surg 2: 1-25, 1992
34. Herrera JL, Lyons MF II, Johnson LF: Saliva: Its role in health and disease. J Clin Gastroenterol 10: 569-578, 1988
35. Zelles T, Purushotham KR, Macauley SP, Oxford GE, and Humphreys-Beher MG: Saliva and growth factors: The fountain of youth within us all. J Dent Res 74: 1826-1832, 1995