Sensitization to acid induced by sodium ions in Escherichia coli: Dependence on (p)ppGpp and cAMP and suppression of the relA-associated defect by mutations in envZ

Microbios

Volumn 85, Issue 344, 1996, Pages 161-177

  Rowbury, Robin J ^a   Goodson, Margaret ^a   Lazim, Zoulikha ^a   Humphrey, Tom J ^b  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b PUBLIC HEALTH ENGLAND   (United Kingdom)

Author keywords

(p)ppGpp; Acetate; Acid; cAMP; envZ; Escherichia coli; Glucose; NhaB; relA; Sodium ion; tonB

Indexed keywords

CYCLIC AMP; ENVZ PROTEIN, E COLI; ERYTHROMYCIN; ESCHERICHIA COLI PROTEIN; GUANOSINE 3' DIPHOSPHATE 5' DIPHOSPHATE; GUANOSINE 3',5' POLYPHOSPHATE SYNTHETASES; GUANOSINE 3',5'-POLYPHOSPHATE SYNTHETASES; HYDROCHLORIC ACID; LIGASE; MULTIENZYME COMPLEX; OUTER MEMBRANE PROTEIN; RIFAMPICIN; SODIUM CHLORIDE; VANCOMYCIN;

ARTICLE; DRUG EFFECT; ESCHERICHIA COLI; GENE REPRESSION; GENETICS; METABOLISM; PH;

BACTERIAL OUTER MEMBRANE PROTEINS; CYCLIC AMP; ERYTHROMYCIN; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; GUANOSINE TETRAPHOSPHATE; HYDROCHLORIC ACID; HYDROGEN-ION CONCENTRATION; LIGASES; MULTIENZYME COMPLEXES; RIFAMPIN; SODIUM CHLORIDE; SUPPRESSION, GENETIC; VANCOMYCIN;

EID: 0029692581     PISSN: 00262633     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (26)

1. BIELECKI J., Hrebenda J. and Kwiatowski Z. 1982. Mutants of Escherichia coli sensitive to acidic pH. J. gen. Microbiol. 128 1731-3.
2. CSONKA L. N. 1989. Physiological and genetical responses of bacteria to osmotic stress. Microbiol. Rev. 53 121-47.
3. ELLIOTT E. L. and Colwell R. R. 1985. Indicator organisms for estuarine and marine waters. FEMS Microbiol. Rev. 32 61-79.
4. FOSTER J. W. and Hall H. K. 1991. Inducible pH homeostasis and the acid tolerance response of Salmonella typhimurium. J. Bact. 173 5129-35.
5. GIANELLA R. A., Broitman S. A. and Zamcheck N. 1972. Gastric acid barrier to ingested microorganisms in man: studies in vivo and In vitro. Gut 13 251-6.
6. HEEFNER D. L. and Harold F. M. 1980. ATP-linked sodium transport in Streptococcus faecalis. 1. The sodium circulation. J. biol. Chem. 255 11396-402.
7. JENKINS D. E., Chaisson S. A. and Matin A. 1990. Starvation-induced cross-protection against osmotic challenge in Escherichia coli. J. Bact. 172 2779-81.
8. 2-challenge in Escherichia coll. J. Bact. 170 3910-4.
9. JENSEN M. S. and Bainton D. F. 1973. Temporal changes in pH within the phagocytic vacuole of the polymorphonuclear neutrophilic leukocyte. J. cell Biol. 56 379-88.
10. + ions. J. biol. Chem. 266 21753-9.
11. LEE A. and Gemmell E. 1972. Changes in the mouse intestinal microflora during weaning: role of volatile fatty acids. Infect. Immunol. 5 1-7.
12. MORONA R., Kramer C. and Henning U. 1985. Bacteriophage receptor area of the outer membrane protein OmpA of Escherichia coli K12. J. Bact. 164 539-43.
13. NIKAIDO H. and Vaara M. 1985. Molecular basis of bacterial outer membrane permeability. Microbiol. Rev. 49 1-32.
14. OHYAMA T., Imaizumi R., Igarashi K. and Kobayashi H. 1992. Escherichia coli is able to grow with negligible sodium ion extrusion activity at alkaline pH. J. Bact. 174 7743-9.
15. + gene in the regulation of the lac operon. J. Bact. 145 410-6.
16. 1-diphosphate. Proc. natn. Acad. Sci. USA 76 1726-30.
17. RAHAV-MANOR O., Carmel O., Karpel R., Taglicht D., Glaser G., Schuldiner S. and Padan E. 1992. NhaR, a protein homologous to a family of bacterial regulatory proteins (LysR), regulates nhaA, the sodium proton antiporter gene in Escherichia coli. J. biol. Chem. 267 10433-8.
18. RAJA N., Goodson M., Smith D. G. and Rowbury R. J. 1991a. Habituation to acid in Escherichia coli: conditions for habituation and its effects on plasmid transfer. J. appl. Bact. 70 59-65.
19. RAJA N., Goodson M., Chui W. C. M., Smith D. G. and Rowbury R. J. 1991b. Decreased DNA damage by acid and increased repair of acid-damaged DNA in acid-habituated Escherichia coli. J. appl. Bact. 70 507-11.
20. REAKES C. F. L., Deeney C. M. M., Goodson M. and Rowbury R. J. 1988. Suppression by the ColV, I-K94 plasmid of inhibitor sensitivities in ompA mutants of Escherichia coli. Can. J. Microbiol. 34 148-56.
21. ROWBURY R. J., Goodson M. and Humphrey T. J. 1994. Sodium chloride induces an NhaA/NhaR-independent acid sensitivity at neutral external pH in Escherichia coli. Appl. Environ. Microbiol. 60 1630-4.
22. ROWBURY R. J., Goodson M. and Wallace A. D. 1992. The PhoE porin and transmission of the chemical stimulus for induction of acid resistance (acid habituation) in Escherichia coli. J. appl. Bact. 72 233-43.
23. ROWBURY R. J. and Goodson M. 1993. PhoE porin of Escherichia coli and phosphate reversal of acid damage and killing and of acid induction of the CadA gene product. J. appl. Bact. 74 652-61.
24. SALMOND C. V., Kroll R. G. and Booth I. R. 1984. The effect of food preservatives on pH homeostasis in Escherichia coli. J. gen. Microbiol. 130 2845-50.
25. SMALL P., Blankenhorn D., Welty D., Zinser E. and Slonczewski J. L. 1994. Acid and base resistance in Escherichia coli and Shigella flexneri: role of rpoS and growth pH. J. Bact. 176 1729-37.
26. THOMAS A. D. and Booth I. R. 1992. The regulation of expression of the porin gene ompC by acid pH. J. gen. Microbiol. 138 1829-35.