Altered β-APP Metabolism after Head Injury and its Relationship to the Aetiology of Alzheimer's Disease

Acta Neurochirurgica, Supplement

Volumn 1996, Issue 66, 1996, Pages 96-102

  Graham, D I ^a,e   Gentleman, S M ^b   Nicoll, J A R ^a   Royston, M C ^b   McKenzie, J E ^b   Roberts, G W ^c   Griffin, W S T ^d  

^a UNIVERSITY OF GLASGOW   (United Kingdom)

^b IMPERIAL COLLEGE SCHOOL OF MEDICINE   (United Kingdom)

^c GLAXOSMITHKLINE   (United Kingdom)

^d ARKANSAS CHILDREN S HOSPITAL RESEARCH INSTITUTE   (United States)

^e SOUTHERN GENERAL HOSPITAL   (United Kingdom)

Author keywords

Deposition of A ; Head injury; APP expression

Indexed keywords

AMYLOID PRECURSOR PROTEIN;

ALZHEIMER DISEASE; BRAIN; BRAIN INJURY; CHRONIC BRAIN DISEASE; GENE EXPRESSION; GENETICS; HUMAN; METABOLISM; PATHOLOGY; PHYSIOLOGY; REVIEW; UPREGULATION;

ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN PRECURSOR; BRAIN; BRAIN DAMAGE, CHRONIC; BRAIN INJURIES; GENE EXPRESSION; HUMANS; UP-REGULATION;

EID: 0029688554     PISSN: 00651419     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-3-7091-9465-2_17     Document Type: Article

References (53)

1. Abe K, Tanzi RE, Kogure K (1991) Selective induction of Kunitz-type protein: inhibitor domain containing amyloid precursor protein in RNA after persistent focal ischaemia in rat cerebral cortex. Nenrosci Lett 125: 172-174
2. Betard C, Robitaille Y, Gee M, Tiberghien D, Larrivee D, Roy P, Mortimer JA, Gauvreau D (1994) Apo E allele frequencies in Alzheimer's disease, Lewy body dementia. Alzheimer's disease with cerebrovascular disease and vascular dementia. Neuroreport 5: 1893-1896
3. Braak H, Braak E (1991) Neuropathological staging of Alzheimer-relaled changes. Acta Neuropathol 82: 239-259
4. Buxbaum JD, Oishi M, Chem HI, Pinkas-Kramarski R, Jaffe EA, Gandy SE, Greengard P (1992) Cliolinergic agonists and interleukin I regulate processing and secretion of the Alzheimer β/A4 amyloid protein precursor. Proc Nat Acad Sci USA 89: 10075-10078
5. Chartier-Harlin M-C, Parfitt M, Legrain S, Perez-Tur J, Brousseau T, Evans A, Berr C, Vidal O, Roques P, Gourlet V, Fruchart JC, Delacourte A, Rosser M, A Mouyet P (1994) Apolipoprotein E4 alelle as a major risk factor for sporadic early-and late-onset forms of Alzheimer's disease: analysis of the 19q 13.2 chromosomal region. Hum Mol Genet 3: 569-574
6. Clinton J, Ambler MW, Roberts GW (1991) Post-traumatic Alzheimer's disease: preponderance of a single plaque type. Neuropathol Appl Neurobiol 17: 69-74
7. Corder EH, Saunders AM, Strittmatter WJ, Schmechel DE, Gaskell PC, Small GW, Roses AD, Haines JL, Pericak Vance MA (1993) Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families. Science 261: 921-923
8. Corder EH, Saunders AM, Risch NJ, Strittmatter WJ, Schmechel DE, Gaskell PC, Rimmeler JB, Locke PA, Connecally PM, Schmader KE, Small GW, Roses AD, Haines JL, Pericak Vance MA (1994) Protective effect of apolipoprotein E type 2 allele for late onset Alzheimer disease. Nature Genet 7: 180-184
9. Corsellis JAN, Bruton CJ, Kreeman-Browne D (1973) The aftermath of boxing. Psychol Med 3: 270-273
10. Dai XY, Nanko S, Hattori M, Fukuda R, Nagata K, Isse K, Uski A, Kazamatsuri H (1994) Association of apolipoprotein E4 with sporadic Alzheimer's disease is more pronounced in early onset type. Nenrosci Lett 175: 74-76
11. Gentleman SM, Graham DI, Roberts GW (1993) Molecular pathology of head injury: altered β-APP metabolism and the aetiology of Alzheimer's disease. Prog Brain Res 96: 237-246
12. Goate A, Chartier-Harlin M-C, Mullan M (1991) Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease. Nature 349: 704-706
13. Goldgaber D, Lerman MI, McBride OW, Safliotti U, Gajdusek DC (1987) Characterization and chromosomal localization of a DNA including brain amyloid of Alzheimer's disease. Science 235: 877-880
14. Goldgaber D, Harris HW, Hla T, Maciag T, Donnelly RG, Jacobsen JS, Vitek MP, Gajdusek DC (1989) Interleukin 1 regulates synthesis of amyloid β protein precursor mRN A in human endothelial cells. Proc Nat Acad Sci USA 86: 7606-7610
15. Graham DI, Gentleman SM, Lynch A, Roberts GW (1995) Distribution of β- amyloid protein in the brain following severe head injury. Neuropathol Appl Neurobiol 21: 27-34
16. Graham DI, Ford I, Adams JH, Doyle D, Teasdale GM, Lawrence AE, McLellan DR (1989) Ischaemic brain damage is still common in fatal non-missile head injury. J Neurol Neurosurg Psychiatry 52: 346-350
17. Griffin WST, Shen JG, Gentleman SM, Graham DI, Mrak RE, Roberts GW (1994) Microglial Interleukin-1α expression in human head injury: correlations with neuronal and neuritic β-amyloid precursor protein expression. Neurosci Lett 176: 133-136
18. Huber A, Gabbert K, Keleman J, Cervos-Navarro J (1993) Density of amyloid plaques in brain after head trauma. J Neurotrauma 10 [Suppl 1]: S180
19. Kang J, Lemaire HG, Unterbeck A, Salbaum JM, Masters CL, Grzeschik KH, Multhaup G, Beyreuther K, Muller-Hill B (1987) The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor. Nature 325: 733-736
20. Kawarbayashi T, Shoji M, Harigaya Y, Yamaguchi H, Hirai S (1991) Expression of APP in the early stages of brain damage. Brain Res 563: 334-338
21. Marshak DR, Pesce SA, Stanley LC, Griffin WST (1991) Increased S 100β-neurotrophic activity in Alzheimer's disease temporal lobe. Neurobiol Aging 13: 1-7
22. Mayeux R, Ottman R, Tang M-X, Noboabauza L, Marder K, Gurland B, Stern Y (1993). Genetic susceptibility and head injury as risk factors for Alzheimer's disease amongst community-dwelling elderly persons and their first-degree relatives. Ann Neurol 33: 494-501
23. Mayeux R, Ottman R, Maestre G, Ngae BS, Tang M-X, Ginsburg H, Chun M, Tycko B, Shelanski M, Synergistie effects of traumatic head injury and apolipoprotein-ε in patients with Alzheimer's disease. Neurology 45: 555-557
24. McKenzie JE, Gentleman SM, Roberts GW, Graham DI, Royston MC Increased numbers of β-APP immunoactive neurons in the entorhinal cortex after head injury. Neuroreport 6: 161-164
25. Mortimer JA, Van Duijn CM, Chandra V (1991) Head trauma as a risk factor for Alzheimer's disease: a collaborative re-analysis of case-control studies. Int. J Epidemiol 20 [Suppl 2]: S28-35
26. Mrak RE, Sheng JE, Griffin WST (1995) Glial cytokines in Alzheimer's disease. Review and pathogenetic implications. Hum Pathol 26: 816-823
27. Nakamura Y, Takeda M, Niigawa H, Hariguchi S, Nishimura T (1992) Amyloids-protein precursor deposition in rat hippocampus lesioned by ibotenic acid injection. Neurosci Lett 136: 95-98
28. Nicoll JAR, Roberts GW, Graham DI (1995) Apolipoprotein Eε4 allele is associated with deposition of amyloid β-protein following head injury. Nature Medicine 1: 135-137
29. Okuizumi K, Onodera O, Tanaka H, Kobayashi H, Tsuji S, Takahashi H, Oyanagi K, Seki K, Tanaka M, Naruse S, Miyatake T, Mizusawa H, Kanazawa I (1994) Apoe-4 and early onsel Alzheimer's. Nature Genet 7: 10-11
30. Pericak-Vance MA, Bebout JL, Gaskell PC, Yamaoka LH, Hung WY, Alberts MJ, Walker AP, Bartlell RJ, Haynes CA, Welsh KA, Earl NL, Heyman A, Clark CM, Roses AD (1991) Linkage studies in familial Alzheimer's disease: evidence for chromosome 19 linkage. Am J Hum Genet 48: 1034-1050
31. Pluta R, Kida E, Lossinsky AS, Golabak AA, Mossakowski MJ, Wisniewski HM (1994) Complete cerebral ischaemia with short-term survival in rats induced by cardiac arrest. Extracellular accumulation of Alzheimer's β-amyloid protein precursor in the brain. Brain Res 649: 323-328
32. Quon C, Wang Y, Catalano R, Marian Scardina J, Murakami K, Cordell B (1991) Formation of β-amyloid protein deposits in brains of transgenic mice. Nature 352: 239-241
33. Roberts GW, Allsop D, Bruton CJ (1990) The occult aftermath of boxing. J Neurol Neurosurg Psychiatry 53: 373-378
34. Roberts GW, Whitwell HL, Acland PR, Bruton CJ (1990) Dementia in a punch-drunk wife. Lancet 335: 918-919
35. Roberts GW, Gentleman SM, Lynch A, Graham DI (1991) βA4 amyloid protein deposition in brain after head trauma. Lancet 338: 1422-1423
36. Roberts GW, Gentleman SM, Lynch A, Murray L, Landon M, Graham DI (1994) βA4 amyloid protein deposition in brain after severe head injury: implications for the pathogenesis of Alzheimer's disease. J Neurol Neurosurg Psychiatry 57: 419-425
37. Rogers J, Cooper NR, Webster S, Schultz J, McGeer PL, Styren SD, Civin WH, Brachova L, Bradt B, Ward P (1992) Complement activation by β-Amyloid in Alzheimer's disease. Proc Nat Acad Sci 89: 10016-10020
38. Royston MC, Rothwell NJ, Roberts GW (1992) Alzheimer's disease: aetiology: pathology to potential treatments. Trends Pharmacol Sci 13: 131-133
39. Saunders AM, Strittmatter WJ, Schmechel D, St George-Hyslop PH, Pericak-Vance MA, Joo SH, Rosi BL, Gusella JF, Crapper Maclachlan DR, Alberts MJ, Hulette C, Crain B, Goldgaber D, Roses AD (1993) Association of apolipoprotein F allele 4 with late-onset familial and sporadic Alzheimer's disease. Neurology 43: 1467-1472
40. Schellenberg GD, Bird TD, Wijsman EM, Orr HT, Anderson L, Nemens E, White JA, Bonny-Castle L, Weber JL, Alonso ME, Potter H, Heston LL, Martin GM (1992) Genetic linkage evidence for a familial Alzheimer's disease/locus on chromosome 14. Science 258: 668-671
41. Yu C-E, Payami H, Olson JM, Boehnke M, Wijsman EM, Orr HT, Kukull WA, Goddard KAB, Nemens E, White JA, Alonso ME, Taylor TD, Ball MJ, Kaye J, Morris J, Chui H, Sadovnick AD, Martin GM, Larson FB, Heston LL, Bird TD, Schellenberg GD (1994) The Apolipoprotein E/C1/C11 gene cluster and late-onset Alzheimer's disease. Am J Hum Genet 54: 631-642
42. Scott JN, Parhad IM, Clark AW (1991) β-Amyloid precursor protein gene is differentially expressed in axonotomized sensory and motor systems. Mol Brain Res 10: 315-325
43. Sheng JE, Boup FA, Mrak RE, Griffin WST (1994) Increased neuronal Beta-amyloid precursor protein expression in human temporal lobe epilepsy: association with interleukin 1 alpha immunoreactivity. J Neurochem 63: 1872-1879
44. Sparks DL, Liu H, Scheff SW, Coyne CM, Hunsaker JC (1993) Temporal sequence of plaque formation in the cerebral cortex of non-demenlia individuals. J Neuropathol Exp Neurol 52: 135-142
45. Stanley LC, Griffin WST (1990) Localization of IL-1α and IL-1β in diseases with gliosis, dementia and immune suppression. Soc Neurosci 16: 1345
46. Tatemichi TK, Paik M, Bagiella E, Desmond DW, Stern Y, Sano M, Hauser WA, Mayeux R (1994) Risk of dementia after stroke in a hospitalized cohort: Results of a longitudinal study. Neurology 44: 1885-1891
47. Tomimoto H, Wakita H, Akiguchi I, Nakamura S, Kimura J (1994) Temporal profiles of accumulation of amyloid βA4 protein precursor in the gerbil after ischaemic stress. J Cereb Blood Flow Metab 14: 565-573
48. Tomlinson BE (1992) Aging and the Dementias. In: Adams JH, Duncan LW (Eds), Greenfields neuropathology. 5th Ed. Edward Arnold, London, pp 1284-1410
49. Tsai M-S, Tangalos EG, Peterson RC, Smith GE, Schaid DJ, Kokmen E, Ivnik RJ, Thibodeau SN (1994) Apolipoprotein E: risk factor for Alzheimer's disease. Am J Hum Genet 6: 643-649
50. Utermann G, Kindermann I, Kaffarnik H, Steinmetz A (1984) Apolipoprotein E phenolypes and hyporlipidemia. Hum Genet 65: 232-236
51. Van Broeckhoven CL (1995) Molecular genetics of Alzheimer disease: identification of genes and gene mutations. Europ Neurol 35: 8-19
52. Van Denabelle P, Fiers W (1991) Is amyloidogenesis during Alzheimer's disease due to an IL-1/IL-6- mediates "acute phase response" in the brain? Immunol Today 12: 217-219
53. Van Duijn CM, de Kinijff P, Cruts M, Wehnert A, Havekes LM, Hofman A, Van Broeckhoven C (1994) Apolipoprotein E4 allele in a population-based study of early-onset Alzheimcr's disease. Nature Genet 7: 74-78