Influences of a low molecular humic substance (HS1500) on selected reproductive parameters in male rats;Untersuchungen zum einfluß eines niedermolekularen synthetischen huminstoffes auf ausgewählte reproduktionsparameter männlicher ratten

Deutsche Tierarztliche Wochenschrift

Volumn 103, Issue 1, 1996, Pages 10-12

  Faqi, A S ^a,b   Lange, N ^a,b   Kuhnert M ^a,c   Haase, A ^a,c   Hoke H ^a,c   Seubert, B ^a,c  

^a Fa Weyl GmbH   (Germany)

^b UNIVERSITY OF LEIPZIG   (Germany)

^c Fa Weyl GmbH

Author keywords

[No Author keywords available]

Indexed keywords

FOLLITROPIN; HS 1500; HYDROXYBENZOIC ACID DERIVATIVE; LUTEINIZING HORMONE;

ANIMAL; ARTICLE; BLOOD; DRUG EFFECT; EPIDIDYMIS; GROWTH, DEVELOPMENT AND AGING; MALE; ORAL DRUG ADMINISTRATION; ORGAN SIZE; RAT; SPERMATOGENESIS; TESTIS; WISTAR RAT;

ADMINISTRATION, ORAL; ANIMALS; EPIDIDYMIS; FOLLICLE STIMULATING HORMONE; HYDROXYBENZOIC ACIDS; LUTEINIZING HORMONE; MALE; ORGAN SIZE; RATS; RATS, WISTAR; SPERMATOGENESIS; TESTIS;

EID: 0029688265     PISSN: 03416593     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (40)

1. ALLANSON, M., and R. DENNESLY (1962): Observation on cadmium damage and repair in rat testes and the effects on the pituitary gonadotropins. J. Endocrinology 24, 453-462.
2. - AMANN, R. P. (1970): The male rabbit IV. Quantitative testicular histology and comparisons between daily sperm production as determined historically and daily sperm output. Fertility and Sterility 9, 662-672.
3. - AMANN, R. P. (1982): Use of animal models for detecting specific alterations in reproduction. Fundam. Appl. Toxicol. 2, 13-26.
4. - BARRATT, C. L. R., A. G DAVIES, M. R. BANSAL and M. E. WILLIAMS (1989): The effects of lead on the male rat reproductive system. Andrologia 21, 161-166.
5. - BERNDTSON, W. E. (1977): Methods for quantifying mammalian spermatogenesis: A review. J. Anim. Sci. 44, 818-833.
6. - CHAPIN, R. E., D. R. WHITE, K. T. MORGAN and S. J. BUSS (1994): Studies of lesions induced in the testis and epididymis of F-344 rats by inhaled methyl chloride. Toxicol. Appl. Pharmacol. 76, 328-343.
7. - DAHLBÄCK, M., and Ä. RYRFELDT (1934): Testicular effects of some xanthine derivatives in the rat. Arch. Toxicol. Supp. 7, 159-163.
8. - DALKIN, A. C., A. G. BOURNE, D. R. PIEPER, S. REGIANI and J. C. MARSHALL (1981): Pituitary and gonadal gonadotropin releasing hormone receptors during sexual maturation in the rat. Endocrinology 108, 1658-1664.
9. - DIXON, L. R. (1984): Assessment of chemicals affecting the male reproductive system. Arch. Toxicol. Suppl. 7, 118-127.
10. - DÖHLER, K. D., and W. WUTTKE (1974): Serum LH, FSH, prolactin and progesteron from birth to puperty in female and male rats. Endocrinology 94, 1003-1008.
11. - DRIFE, J. O. (1982): Drugs and sperms. Brit. Med. Bull. 284, 844-845.
12. - ELLIS, G. B., and C. DESJARDINS (1982): Male rats secrete luteinizing hormone and testosterone episodically. Endocrinology 110, 1618-1627.
13. - FAQI, A. S. (1995): Untersuchungen zu reproduktionstoxikologischen Wirkungen hoher Dosen des niedermolekularen synthetischen Huminstoffes HS 1500 an der Laboratoriumsratte. Diss.-Schrift, Univ. Leipzig.
14. - GLAISTER, J. (1986): Principles of toxicological pathology. Taylor & Francis, Philadelphia.
15. - HAYWOOD, R., and W. JAMES (1985): Current laboratory approaches for assessing male reproductive toxicology. In: Dixon, R. L. (Ed.): Testicular toxicity in the laboratory rat. Raven Press, New York.
16. - HOFNUNG, M., and N. WEILL (1980): Inducetest and spermtest in genetic toxicology testing. Arch. Toxicol. 46, 159-169.
17. - HOYER, M. (1995): Reproduktionstoxikologische Untersuchungen zur Beeinflussung männlicher Geschlechtsorgane durch Langzeitapplikation nichtsteroidaler Antiphlogistika am Beispiel Indometacin und deren Interaktionen mit Ethanol an der Blut-Hoden-Schranke. Diss.-Schrift, Univ. Leipzig.
18. - JACKSON, H. (1970): Antispermatogenic agents. Brit. Med. Bull. 26, 79-86.
19. - JOHNSON, F. E., W. G. DOUBEK, K. C. TOLMAN and C. G. JANNEY (1993): Testicular cytotoxicity of intravenous procarbazine in rats. Surg. Oncol. 2, 77-81.
20. - KETELSLEGERS, J.-M., W. D. HETZEL, R. J. SHERID and K. J. CATT (1978). Development changes in testicular gonadotropin receptors: Plasma gonadotropins and plasma testosterone in the rat. Endocrinology 103, 212-222.
21. - KOMATSU, H., T. KAKIZOE, T. NIIJIMA, T. KAWACHIA and T. SUGIMURA (1982): Increased sperm abnormalities due to dietary restrictions. Mutat. Res. 93, 439-446.
22. - LANGE, N., A. S. FAQI, M. KÜHNERT, A. HAASE, H. HÖKE and B. SEUBERT (1995): Untersuchungen zum Einfluß eines niedermolekularen synthetischen Huminstoffes auf die prä- und postnatale Entwicklung bei Ratten. Dtsch. tierärztl. Wschr. 103.
23. - LEIDL, von W., W. SCHEFELS, R. STOLLA and E. METZGER (1971): Differenzierung und Befruchtungsvermögen pathologischer Spermien. Dtsch. tierärztl. Wschr. 78, 129-138.
24. - LUI, R. C., M. C. LAREGINA, D. R. HERBOLD and F. E. JOHNSON (1976): Testicular cytotoxicity of intravenous doxorubicin in rats: J. Ural. 136, 940-943.
25. - MANKES, R. F., R. LEVEFRE, K. F. BENITZ, I. ROSENBLUM, H. BATES, A. I. WALKER, R. ABRAHAM and W. ROCKWOOD (1982): Paternal effects of ethanol in the Long-Evans rat. J. Toxicol. Environ. Health. 10, 871-878.
26. - NEGRO-VILAR, A., L. KRULICH and S. M. McCANN (1973): Changes in serum prolactin and gonadotropins during sexual development of the male rat. Endocrinology 93, 660-664.
27. - NEUMANN, F. (1984): Effects of drugs and chemicals on spermatogenesis. Arch. Toxicol. Suppl. 7, 109-117.
28. - OECD (1983): Guidelines for testing of chemicals. Section 4: Health effects. No. 415: One Generation Reproduction Toxicity Study, Paris.
29. - OJEDA, S. R., and V. D. RAMIREZ (1972): Plasma levels of LH and FSH in maturing rats: Response to hemigonadectomy. Endocrinology 90, 466-472.
30. - OJEDA, S. R., and H. F. URBANSKI (1988): Puperty in the rat. In: Knobil, E., and Neill, F. (Eds.): The physiology of reproduction. Vol. 2. Raven Press, New York.
31. - RIEDE, U. N. (1991): Huminstoffe als Biosignale (Jahresforschungsbericht), Pathologisches Institut der Univ. Freiburg i. Br.
32. - ROBB, W. G., R. P. AMANN and G. J. KILLIAN (1978): Daily sperm production and epididymal sperm reserves of pupertal and adult rats. J. Reprod. Fert. 54, 103-107.
33. - SASKENA, S. K., I. T. LAU and M. C. CHANG (1979): Age dependent changes in the sperm population and fertility in the male rat. Exp. Aging Res. 5, 373-381.
34. - SCHMIDT, B. (1995): Reproduktionstoxikologische Untersuchungen zur Wirkung von Cadmium und Furazolidon und in Kombination auf die Hypothalamus-Hypophysen-Hoden-Achse adulter Wistar-Ratten. Diss.- Schrift, Univ. Leipzig.
35. - SEUBERT, B., U. BEILHARZ, W. FICKERT, G. JEROMIN and U. SPITALER (1987): Verfahren zur Herstellung von niedermolekularen Alkalihuminaten. EP 0281 678 B1 vom 10. 12. 87.
36. - SEUBERT, B., and U. N. RIEDE (1992): Verfahren zur Herstellung von Humaten. EP 0537 427 A1 vom 31.7. 92.
37. - STEIN, K. (1994): Vergleichende Untersuchungen zu ausgewählten pharmakologischen und toxikologischen Eigenschaften verschiedener Huminsäureprodukte. Diss.-Schrift, Univ. Leipzig.
38. - VAN THIEL, D. H., S. J. GAVALER, C. F. COBB, J. R. SHERINS and R. LESTER (1979): Alcohol-induced testicular atrophy in the adult male rat. Endocrinology 105, 888-895.
39. - WEYL (1990): Datenblatt zum Produkt HS 1500. Ausgabe 10.
40. - ZIMMERMANN, H. (1991): Reproduktionstoxikologische Grundlagenuntersuchungen an adulten Böcken des Rattenstammes WIST/Lppt mit Huminsäure und Furazolidon allein und in Kombination. Diss.-Schrift, Univ. Leipzig.