The Effect of Molybdenum-Induced Copper Deficiency on Acute-Phase Protein Concentrations, Superoxide Dismutase Activity, Leukocyte Numbers, and Lymphocyte Proliferation in Beef Heifers Inoculated with Bovine Herpesvirus-1

Journal of Animal Science

Volumn 74, Issue 1, 1996, Pages 211-217

  Arthington, J D ^a   Corah, L R ^a   Blecha, F ^a  

^a KANSAS STATE UNIVERSITY   (United States)

Author keywords

Cattle; Ceruloplasmin; Copper; Fibrinogen; Superoxide Dismutase

Indexed keywords

BOS TAURUS; BOVINAE; BOVINE HERPESVIRUS 1; HERPES; HERPESVIRIDAE; HERPESVIRUS 1; HUMAN HERPESVIRUS 1; PHYTOLACCACEAE;

ACUTE PHASE PROTEIN; CERULOPLASMIN; COPPER; FIBRINOGEN; MOLYBDENUM; PHYTOHEMAGGLUTININ; SUPEROXIDE DISMUTASE;

ANIMAL; ANIMAL DISEASE; ARTICLE; BLOOD; BODY WEIGHT; CATTLE; CATTLE DISEASE; CHEMISTRY; DIET SUPPLEMENTATION; ENZYMOLOGY; ERYTHROCYTE; FEMALE; HERPES VIRUS INFECTION; IMMUNOLOGY; INFECTIOUS BOVINE RHINOTRACHEITIS VIRUS; LEUKOCYTE COUNT; LIVER; LYMPHOCYTE ACTIVATION; PHYSIOLOGY; RANDOMIZATION;

ACUTE-PHASE PROTEINS; ANIMALS; BODY WEIGHT; CATTLE; CATTLE DISEASES; CERULOPLASMIN; COPPER; ERYTHROCYTES; FEMALE; FIBRINOGEN; FOOD, FORTIFIED; HERPESVIRIDAE INFECTIONS; HERPESVIRUS 1, BOVINE; LEUKOCYTE COUNT; LIVER; LYMPHOCYTE ACTIVATION; MOLYBDENUM; PHYTOHEMAGGLUTININS; RANDOM ALLOCATION; SUPEROXIDE DISMUTASE;

EID: 0029687852     PISSN: 00218812     EISSN: None     Source Type: Journal    
DOI: 10.2527/1996.741211x     Document Type: Article

References (35)

1. Arthington, J. D., F. Blecha, L. R. Corah, and D. H. Goodband. 1993. Effect of copper depletion and repletion on neutrophil and lymphocyte function in beef heifers. J. Anim. Sci. 71(Suppl. 1):210(Abstr.).
2. Bala, S., M. L. Failla, and J. K. Lunney. 1991. Alterations in splenic lymphoid cell subsets and activation antigens in copper-deficient rats. J. Nutr. 121:745.
3. Bala, S., J. K. Lunney, and M. L. Failla. 1992. Effects of copper deficiency on T-cell mitogenic responsiveness and phenotypic profile of blood mononuclear cells from swine. Am. J. Res. 53:1231.
4. Baumann, H., and J. Gauldie. 1994. The acute phase response. Immunol. Today 15:74.
5. Blecha, F., S. L. Boyles, and J. G. Riley. 1984. Shipping suppresses lymphocyte blastogenic responses in Angus and Brahman × Angus feeder calves. J. Anim. Sci. 59:576.
6. Boyne, R., and J. R. Arthur. 1986. Effects of molybdenum or iron induced copper deficiency on the viability and function of neutrophils from cattle. Res. Vet. Sci. 41:417.
7. Breazile, J. E. 1988. The physiology of stress and its relationship to mechanisms of disease and therapeutics. Vet. Clin. North Am. 4:441.
8. Chirase, N. K., D. P. Hutcheson, and G. B. Thompson. 1991. Feed intake, rectal temperature, and serum mineral concentrations of feedlot cattle fed zinc oxide or zinc methionine and challenged with infectious bovine rhinotracheitis virus. J. Anim. Sci. 69:4137.
9. Chirase, N. K., D. P. Hutcheson, G. B. Thompson, and J. W. Spears. 1994. Recovery rate and plasma zinc and copper concentrations of steer calves fed organic and inorganic zinc and manganese sources with or without injectable copper and challenged with infectious bovine rhinotracheitis virus. J. Anim. Sci. 72:212.
10. Claypool, D. W., F. W. Adams, H. W. Pendell, N. A. Hartmann, Jr., and J. F. Bone. 1975. Relationship between the level of copper in the blood plasma and liver of cattle. J. Anim. Sci. 41:911.
11. Conner, J. G., P. D. Eckersall, A. Wiseman, T. C. Aitchison, and T. A. Douglas. 1988. Bovine acute phase response following turpentine injection. Res. Vet. Sci. 44:82.
12. Corah, L. R., and J. D. Arthington. 1994. Determining the trace mineral status in cattle. Publication and Video Distribution. Kansas State University Cooperative Extension Service, Manhattan, KS.
13. Cousins, R. J. 1985. Absorption, transport, and hepatic metabolism of Cu and Zn: Special reference to metallothionein and ceruloplasmin. Physiol. Rev. 65:238.
14. Demetriou, J. A., P. A. Drews, and J. B. Gin. 1974. Enzymes. In: R. J. Henry, D. C. Cannon, and J. W. Winkelman (Ed.) Clinical Chemistry (2nd Ed.). p 857. Harper and Row, Hagerstown, MD.
15. Disilvestro, R. A., and J. T. Marten. 1990. Effects of inflammation and copper intake on rat liver and erythrocyte Cu-Zn superoxide dismutase activity levels. J. Nutr. 120:1223.
16. Fridovich, I. 1975. Superoxide dismutases. Annu. Rev. Biochem. 44:147.
17. Halliwell, B. 1984. Superoxide dismutase and the Superoxide theory of oxygen toxicity. A critical appraisal. In: R. Lontie (Ed.) Copper Proteins and Copper Enzymes. Vol. II. p 63. CRC Press, Boca Raton, FL.
18. King, J. 1965. Ceruloplasmin. In: Practical Clinical Enzymology. p 108. Van Nostrand, London.
19. Lannon, B., and J. Mason. 1986. The inhibition of bovine ceruloplasmin oxidase activity by thiomolybdates in vivo and vitro: A reversible interaction. J. Inorg. Biochem. 26:107.
20. Lofgreen, G. P. 1983. Nutrition and management of stressed beef calves. Vet. Clin. North Am. 5:87.
21. Mason, J., M. Lamand, and C. A. Kelleher. 1982. The effects of duodenal infusion of tri-and dithiomolybdate on plasma copper and on the diamine oxidase activity of caeruloplasmin in sheep. J. Comp. Pathol. 92:509.
22. Mulhern, S. A., and L. D. Koller. 1988. Severe or marginal copper deficiency results in a graded reduction in immune status in mice. J. Nutr. 118:1041.
23. Nockels, C. F., J. DeBonis, and J. Torrent. 1993. Stress induction affects copper and zinc balance in calves fed organic and inorganic copper and zinc sources. J. Anim. Sci. 71:2539.
24. NRC. 1984. Nutrient Requirements of Beef Cattle (6th Ed.). National Academy Press, Washington, DC.
25. Orr, C. L., D. P. Hutcheson, R. B. Grainger, J. M. Cummins, and R. E. Mock. 1990. Serum copper, zinc, calcium and phosphorus concentrations of calves stressed by bovine respiratory disease and infectious bovine rhinotracheitis. J. Anim. Sci. 68:2893.
26. Phillippo, M., W. R. Humphries, and P. H. Garthwaite. 1987. The effect of dietary molybdenum and iron on copper status and growth in cattle. J. Agric. Sci. 109:315.
27. Prohaska, J. R. 1983. Changes in tissue growth, concentrations of copper, iron, cytochrome oxidases and Superoxide dismutase subsequent to dietary or genetic copper deficiency in mice. J. Nutr. 113:2148.
28. SAS. 1985. SAS User's Guide: Statistics (Version 5 Ed.). SAS Inst. Inc., Cary, NC.
29. Schalm, O. W. 1986. Cattle: Normal hematology with comments on disease. In: N. C. Jain (Ed.) Schalm's Veterinary Hematology (4th Ed.). p 178. Lea & Febiger, Philadelphia, PA.
30. Solter, P. F., W. E. Hoffmann, L. L. Hungerford, J. P. Siegel, S. H. St. Denis, and J. L. Dorner. 1991. Haptoglobin and ceruloplasmin as determinants of inflammation in dogs. Am. J. Vet. Res. 52:1738.
31. Suttle, N. F., and D. G. Jones. 1989. Recent developments in trace element metabolism and function: trace elements, disease resistance and immune responsiveness in ruminants. J. Nutr. 119:1055.
32. Torre, P. M., R. J. Harmon, D. S. Trammell, and T. W. Clark. 1994. Effects of dietary copper insufficiency on bovine blood mononuclear cell proliferation. J. Anim. Sci. 77(Suppl. 1):107(Abstr.).
33. Ward, J. D., E. B. Kegley, J. W. Spears, and C. L. Warner. 1992. Performance and immune response in growing cattle fed molybdenum and different copper levels and sources. J. Anim Sci. 70(Suppl. 1):32(Abstr.).
34. Windhauser, M. M., L. C. Kappel, J. McClure, and M. Hegsted. 1991. Suboptimal levels of dietary copper vary immunoresponsiveness in rats. Biol. Trace Elem. Res. 30:205.
35. Xin, Z., D. F. Waterman, R. W. Hemken, and R. J. Harmon. 1991. Effects of copper status on neutrophil function, Superoxide dismutase, and copper distribution in steers. J. Dairy. Sci. 74:3078.