NAD-analogues as potential anticancer agents: Conformational restrictions as basis for selectivity

Acta Biochimica Polonica

Volumn 43, Issue 1, 1996, Pages 183-194

  Pankiewicz, Krzysztof W ^a   Zatorski, Andrzej ^b   Watanabe, Kyoichi A ^a  

^a Oncor Inc   (United States)

^b Department of Obstetrics Gynecology   (United States)

Author keywords

Anticancer agents; Inhibitors of IMP dehydrogenase; NAD analogues; Tiazofurin

Indexed keywords

ANTINEOPLASTIC ANTIMETABOLITE; DRUG DERIVATIVE; ENZYME INHIBITOR; INOSINATE DEHYDROGENASE; NICOTINAMIDE ADENINE DINUCLEOTIDE;

ANIMAL; CHEMICAL STRUCTURE; CHEMISTRY; CONFORMATION; DRUG ANTAGONISM; DRUG DESIGN; HUMAN; REVIEW; STEREOISOMERISM; SYNTHESIS;

ANIMALS; ANTIMETABOLITES, ANTINEOPLASTIC; DRUG DESIGN; ENZYME INHIBITORS; HUMANS; IMP DEHYDROGENASE; MOLECULAR CONFORMATION; MOLECULAR STRUCTURE; NAD; STEREOISOMERISM;

EID: 0029687199     PISSN: 0001527X     EISSN: None     Source Type: Journal    
DOI: 10.18388/abp.1996_4552     Document Type: Article

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