Klinische und immunbiologische Betrachtungen zur entzündlichen Aktivität der Sarkoidose

Pneumologie

Volumn 50, Issue 1, 1996, Pages 40-48

  Muller Quernheim J ^a  

^a RESEARCH CENTER BORSTEL   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE;

CD4 CD8 RATIO; HUMAN; IMMUNOLOGY; LUNG ALVEOLUS; LUNG ALVEOLUS MACROPHAGE; LYMPHOCYTE ACTIVATION; PHYSIOLOGY; REVIEW; SARCOIDOSIS; T LYMPHOCYTE;

CD4-CD8 RATIO; CYTOKINES; HUMANS; LYMPHOCYTE ACTIVATION; MACROPHAGES, ALVEOLAR; PULMONARY ALVEOLI; SARCOIDOSIS, PULMONARY; T-LYMPHOCYTES;

EID: 0029687024     PISSN: 09348387     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (101)

1. Asano, M., T. Minagawa, M. Ohmichi, Y. Hiraga: Detection of endogenous cytokines in sera or in lymph nodes obtained from patients with sarcoidosis. Clin. exp. Immunol. 84 (1991) 92-96
2. Bachwich, P. R., J. P. Lynch, J. Larrick, M. Spengler, S. L. Kunkel: Tumor necrosis factor production by human sarcoid alveolar macrophages. Am. J. Pathol. 125 (1986) 421-425
3. Baughman, R. P., E. E. Lower: The effect of corticosteroid or methotrexate therapy on lung lymphocytes and macrophages in sarcoidosis. Am. Rev. Respir. Dis. 142 (1990) 1268-1271
4. Baughman, R. P., S. A. Strohofer, J. Buchsbaum, E. E. Lower: Release of tumor necrosis factor by alveolar macrophages of patients with sarcoidosis. J. Lab. Clin. Med. 115 (1990) 36-42
5. Bellocq, A., D. Lecossier, C. Pierre-Audigier, A. Tazi, D. Valeyre, A. J. Hance: T cell receptor repertoire of T lymphocytes recovered from the lung and blood of patients with sarcoidosis. Am. J. Respir. Crit. Care Med. 149 (1994) 646-654
6. Bocart, D., D. Lecossier, A. de Lassence, D. Valeyre, J.-P. Battesti, A. J. Hance: A search for mycobacterial DNA in granulomatous tissues from patients with sarcoidosis using the polymerase chain reaction. Am. Rev. Respir. Dis. 145 (1992) 1142-1148
7. Bost, T. W., D. W. H. Riches, B. Schumacher et al.: Alveolar macrophages from patients with beryllium disease and sarcoidosis expressincreased levels of mRNA for tumor necrosis factor-α and interleukin-6 but not interleukin-1β. Am. J. Respir. Cell Mol. Biol. 10 (1994) 506-513
8. Car, B. D., F. Meloni, M. Luisetti, G. Semenzato, G. Gialdroni-Grassi, A. Walz: Elevated IL-8 and MCP-1 in the bronchoalveolar lavage fluid of patients with idiopathic pulmonary fibrosis and pulmonary sarcoidosis. Am. J. Respir. Crit. Care Med. 149 (1994) 655-659
9. Curtis, J., P. Byrd, M. Warnock, H. Kaltreider: Requirement of CD4-positive T cells for cellular recruitment to the lungs of mice in response to a particulate intratracheal antigen. J. Clin. Invest. 88 (1991) 1244-1254
10. DeRemee, R.: The present status of treatment of pulmonary sarcoidosis: A house divided. Chest 71 (1977) 388-393
11. Devergne, O., D. Emilie, M. Peuchmaur, M. C. Crevon, M. F. D'Agay, P. Galanaud: Production of cytokines in sarcoid lymph nodes: Preferential expression of interleukin-1β and interferon-γ genes. Hum. Pathol. 23 (1992) 317-323
12. Dohi, M., K. Yamamoto, K. Masuko et al.: Accumulation of multiple T Cell clonotypes in lungs of healthy individuals and patients with pulmonary sarcoidosis. J. Immunol. 152 (1994) 1983 -1988
13. DuBois, R. M., M. Kirby, B. Balbi, C. Saltini, R. G. Crystal: T-lymphocytes that accumulate in the lung in sarcoidosis have evidence of recent stimulation of the T-cell antigen receptor. Am. Rev. Respir. Dis. 145 (1992) 1205-1211
14. Eklund, A., E. Blaschke: Elevated serum neopterin in sarcoidosis. Lung 164 (1986) 325-332
15. Endres, P., J. Müller-Quernheim: Alveolitiden und granulomatöse Lungenerkrankungen. In: Ferlinz, R. (ed.): Pneumologie in Klinik und Praxis. Thieme, Stuttgart 1994, S. 487-540
16. Forman, J., J. Klein, R. Silver, M. Liu, B. Greenlee, D. Moller: Selective activation and accumulation of oligoclonal Vβ-specific T cells in active pulmonary sarcoidosis. J. Clin. Invest. 94 (1994) 1533-1542
17. Forrester, J., L. Newman, Y. Wang, T. King, B. Kotzin: Clonal expansion of lung Vδ1+ cells in pulmonary sarcoidosis. J. Clin. Invest. 91 (1993) 292-300
18. Gilbert, S., D. S. Steinbrech, S. K. Landas, G. W. Hunninghake: Amounts of angiotensin-converting enzyme mRNA reflect the burden of granulomas in granulomatous lung disease. Am. Rev. Respir. Dis. 148 (1993) 483-486
19. Girgis, R., M. Basha, M. Maliarik, J. J. Popovich, M. Iannuzzi: Cytokines in the bronchoavleolar lavage fluid of patients with active pulmonary sarcoidosis. Am. J. Respir. Crit. Care Med. 152 (1995) 71-75
20. Greene, W. C.: Sarcoidosis and interleukin-2 receptors. Am. Rev. Respir. Dis. 137 (1988) 757-756
21. Grunewald, J., C. H. Janson, A. Eklund et al.: Restricted Vα 2.3 gene usage by CD4+ T lymphocytes in bronchoalveolar lavage fluid from sarcoidosis patients correlates with HLA-DR3. Eur. J. Immunol. 22 (1992) 129-135
22. Grunewald, J., M. Shigematsu, S. Nagai, T. Mikuniya, T. Izumi, A. Eklund: T-cell receptor V gene expression in HLA-typed Japanese patients with pulmonary sarcoidosis. Am. J. Respir. Crit. Care Med. 151 (1995) 151-156
23. Hagerstrand, I., F. Linell: The prevalence of sarcoidosis in the autopsie material of a swedish town. Acta Med. Scan. Suppl. 425 (1964) 171-173
24. Haley, P., G. Finch, J. Mewhinney et al.: A canine model of Beryllium-induced granulomatous lung disease. Lab. Invest. 61 (1989) 219-227
25. Hamacher, J., T. Schaberg: Adhesion molecules in lung diseases. Lung 172 (1994) 189-213
26. Hance, A. J., S. Douches, R. J. Winchester, V. J. Ferrans, R. G. Crystal: Characterization of mononuclear phagocyte subpopulations in the human lung by using monoclonal antibodies: Changes in alveolar macrophage phenotype associated with pulmonary sarcoidosis. J. Immunol. 134 (1985) 284-292
27. Hillerdal, G., E. Nöu, K. Osterman, B. Schmekel: Sarcoidosis: Epidemiology and Prognosis. A 15-year European Study. Am. Rev. Respir. Dis. 130 (1984) 29-32
28. Holter, J., H. Park, K. Sjoerdsma, Y. Kataria: Nonviable autologous bronchoalveolar lavage cell preparations induce intradermal epithelioid cell granulomas in sarcoidosis patients. Am. Rev. Respir. Dis. 145 (1992) 864-871
29. Homolka, J., J. Lorenz, H. D. Zuchhold, J. Müller-Quernheim: Evaluation of soluble CD14 and serum neopterin as serum parameters of inflammatory activity of pulmonary sarcoidosis. Clin. Investig. 70 (1992) 909-916
30. Homolka, J., J. Müller-Quernheim: Increased interleukin 6 production by bronchoalveolar lavage cells in patients with active sarcoidosis. Lung 171 (1993) 173-183
31. Huang, H., K. C. Meyer, L. Kubai, R. Auerbach: An immune model of Beryllium-induced pulmonary granulomata in mice. Histopathology, immune reactivity, and flow-cytometric analysis of bronchoalveolar lavage-derived cells. Lab. Invest. 67 (1992) 138 -146
32. Huber, C., J. R. Batchelor, D. Fuchs et al.: Immun response-associated production of neopterin: Release from macrophages primarily under control of interferon-gamma. J. exp. Med. 160 (1984) 310-316
33. Hunninghake, G. W.: Release of interleukin-1 by alveolar macrophages of patients with active pulmonary sarcoidosis. Am. Rev. Respir. Dis. 129 (1984) 569-572
34. Brady: Role of interleukin-2 release by lung T-cells in active pulmonary sarcoidosis. Am. Rev. Respir. Dis. 128 (1983) 634-636
35. Hunninghake, G. W., S. Gilbert, R. Pueringer et al.: Outcome of the treatment of sarcoidosis. Am. J. Respir. Crit. Care Med. 1949 (1994) 893-898
36. Jones Williams, W.: Beryllium disease. In: James, D. (ed.): Sarcoidosis and other granulomatous disorders. Marcel Dekker, New York 1994, S. 707-721
37. Kataria, Y.: Chlorambucil in sarcoidosis. Chest 78 (1980) 36-43
38. Katz, S.: Clinical presentation and natural history of sarcoidosis. In: Fanburg, B. L. (ed.): Sarcoidosis and other granulomatous diseases of the lung. Dekker, Basel 1983, S. 3-36
39. Klein, J., T. Horn, J. Forman, R. Silver, A. Tierstein, D. Moller: Selection of oligoclonal Vβ-specific T cells in the intradermal response to Kveim-Siltzbach reagent in individuals with sarcoidosis. J. Immunol. 154 (1995) 1450-1460
40. Konishi, K., D. R. Moller, C. Saltini, M. Kirby, R. G. Crystal: Spontaneous expression of the interleukin 2 receptor gene and presence of functional interleukin 2 on T-lymphocytes in the blood of individuals with active pulmonary sarcoidosis. J. Clin. Invest 82 (1988) 775-781
41. Kreiss, K., F. Miller, L. S. Newman, E. A. Ojo-Arnaize, M. D. Rossman, C. Saltini: Chronic Beryllium disease - from the workplace to cellular immunology, molecular immunogenetics, and back. Clin. Immunol. Immunopathol. 71 (1994) 123-129
42. Kreiss, K., M. M. Mroz, B. Zhen, J. W. Martyny, L. S. Newman: Epidemiology of beryllium sensitization and disease in nuclear workers. Am. Rev. Respir. Dis. 148 (1993) 985-991
43. Kroemer, G., G. Wick: The role of interleukin-2 in autoimmunity. Immunology Today 10 (1989) 246-251
44. Kumar, V., D. H. Kono, J. L. Urban, L. Hood. The T-cell repertoire and autoimmun diseases. Annual review of Immunology 7 (1989) 657-682
45. Kunkel, S. L., S. W. Chensue, R. M. Strieter, J. P. Lynch, D. G. Remick: Cellular and molecular aspects of granulomatous inflammation. Am. J. Respir. Cell Mol. Biol. 1 (1989) 439-447
46. Lacronique, J. G., S. I. Rennard, P. B. Bitterman, T. Ozaki, R. G. Crystal: Alveolar macrophages in idiopathic pulmonary fibrosis have glucocorticoid receptor, but glucocorticoid therapy does not suppress alveolar macrophage release of fibronectin and alveolar macrophage derived growth factor. Am. Rev. Respir. Dis. 130 (1984) 450-456
47. Lamb, J. R., V. Bal, P. Mendez-Samperio et al.: Stress proteins may provide a link between the immune response to infection and autoimmunity. Internat. Immunol. 1 (1989) 191-196
48. Lawrence, E. C., K. P. Brousseau, M. B. Berger, C. C. Kurman, L. Marcon, D. L. Nelson: Elevated concentration of soluble interleukin-2 receptors in serum samples and bronchoalveolar fluids in active sarcoidosis. Am. Rev. Respir. Dis. 137 (1988) 759-764
49. Lem, V. M., M. F. Lipscomb, J. C. Weissler et al.: Bronchoalveolar cells from sarcoid patients demonstrate enhanced antigen presentation. J. Immunol. 135 (1985) 1766-1771
50. Longcope, W., O. Freiman: A study of sarcoidosis. Medicine 31 (1952) 132
51. Martinet, Y., P. Pinkston, C. Saltini, J. Spurzem, J. Müller-Quernheim, R. G. Crystal: Evaluation of the in vitro and in vivo effects of cyclosporine on the T-lymphocyte alveolitis of active pulmonary sarcoidosis. Am. Rev. Respir. Dis. 138 (1988) 1242-1248
52. Mende, D., R. Suchenwirth: Neurosarkoidose, vergleichende Analyse des klinischen Profils anhand von 537 Beobachtungen aus der Weltliteratur bis 1963 und von 1976-1988. Fortschr. Neurol. Psychiat. 58 (1990) 7-18
53. Moller, D. R., K. Konishi, M. Kirby, B. Balbi, R. G. Crystal: Bias toward use of a specific T-cell receptor β-chain variable region in a subgroup of individuals with sarcoidosis. J. Clin. Invest. 82 (1988) 1183-1191
54. Moolman, J. A., P. G. Bardin, D. J. Rossouw, J. R. Joubert: Cyclosporin as a treatment for interstitial lung disease of unknown aetiology. Thorax 46 (1991) 592-595
55. Müller-Quernheim, J.: Sarkoidose. In: Krück, E., W. Kaufmann, H. Bünte, E. Gladtke, R. Tölle (eds.): Therapie - Handbuch. Urban & Schwarzenberg, München 1989, S. 465-470
56. Müller-Quernheim, J., M. Krönke, J. Strausz, M. Schykowski, R. Ferlinz: Interleukin-2 receptor gene expression by bronchoalveolar lavage lymphocytes in pulmonary sarcoidosis. Am. Rev. Respir. Dis. 140 (1989) 82-88
57. Müller-Quernheim, J., S. Pfeifer, D. Männel, J. Strausz, R. Ferlinz: Lung restricted activation of the alveolar macrophage/monocyte system in pulmonary sarcoidosis. Am. Rev. Respir. Dis. 145 (1992) 187-192
58. Müller-Quernheim, J., S. Pfeifer, J. Strausz, R. Ferlinz: Correlation of clinical and immunologic parameters of the inflammatory activity of pulmonary sarcoidosis. Am. Rev. Respir. Dis. 144 (1991) 1322-1329
59. Müller-Quernheim, J., C. Saltini, P. Sondermeyer, R. G. Crystal: Compartementalized activation of the interleukin-2 gene by lung T-lymphocytes in active pulmonary sarcoidosis. J. Immunol. 137 (1986) 3475-3483
60. Müller-Quernheim, J., C. Saltini, J. Spurzem, R. G. Crystal: Staging the alveolitis of sarcoidosis: Dichotomy of the spontaneous release of interleukin-1 and the extent of the T-cell alveolitis. Am. Rev. Respir. Dis. 135 (Suppl.) (1987) A305
61. Müller-Quernheim, J., G. Zissel: Elevated accessory function of alveolar macrophages in pulmonary sarcoidosis. Am. J. Respir. Crit. Care Med. 149 (1994) A262
62. Navarrete, C., G. F. Bottazzo: In search of TCR restriction in autoreactive T cell in human autoimmunity: Why is it so elusive? Clin. Exp. Immunol. 91 (1993) 189-192
63. Nelson, D. L., L. A. Rubin, C. C. Kurman, M. E. Fritz, B. Boutin: An analysis of cellular requirements for the production of soluble interleukin-2 receptors in vitro. J. Clin. Immunol. 6 (1986) 114-120
64. Newman, L.: Beryllium disease and sarcoidosis: Clinical and laboratory links. Sarcoidosis 12 (1995) 7-19
65. Oksanen, V.: Neurosarcoidosis. In: James, D. (ed.): Sarcoidosis and other granulomatous disorders. Marcel Dekker, New York 1994, S. 285-309
66. Olive, K., Y. Kataria: Cutaneous manifestations of sarcoidosis. Relationships to other organ system involvement, abnormal laboratory measurements, and disease course. Arch. Intern. Med. 145 (1985) 1811-1814
67. Paine, R. I., C. H. Mody, A. Chawis, M. A. Spahr, L. A. Turka, G. B. Toews: Alveolar epithelial cells block lymphocyte proliferation in vitro without inhibiting activation. Am. J. Respir. Cell Mol. Biol. 5 (1991) 221-229
68. Pfeifer, S., R. Bartlett, J. Strausz, S. Haller, J. Müller-Quernheim: Beryllium-induced disturbances of the murine immunesystem reflect some phenomena observed in sarcoidosis. Int. Arch. Allergy Imm. 104 (1994) 332-339
69. Pforte, A., A. Brunner, P. Gais et al.: Concomitant modulation of serum-soluble interleukin-2 receptor and alveolar macrophage interleukin-2 receptor in sarcoidosis. Am. Rev. Respir. Dis. 147 (1993) 717-722
70. Pforte, A., C. Gerth, A. Voss et al.: Proliferating alveolar macrophages in BAL and lung function changes in interstitial lung. Eur. Respir. J. 6 (1993) 951-955
71. Pinkston, P., P. B. Bitterman, r. G. Crystal: Spontaneous release of interleukin-2 by lung T-lymphocytes in active pulmonary sarcoidosis. N. Engl. J. Med. 308 (1983) 793-800
72. Prior, C., A. Frank, D. Fuchs et al.: Urinary neopterin excretion in pulmonary sarcoidosis: correlation to clinical course of disease. Clin. Chim. Acta 177 (1988) 211-220
73. 2 release, alveolitis, and disease severity in sarcoidosis. Chest 103 (1993) 832-838
74. Raghu, G., W. J. Depaso, K. Cain et al.: Azathioprine combined with prednisone in the treatment of idiopathic pulmonary fibrosis: a prospective double-blind, randomized, placebo-controlled clinical trial. Am. Rev. Respir. Dis. 144 (1991) 291-196
75. Rao, N., Y. Naidu, R. Bell et al.: Usage of T cell receptor β-chain variable gene is highly restricted at the site of inflammation in murine autoimmune uveitis. J. Immunol. 150 (1993) (12) 5716-5721
76. Reske-Kunz, A. B., H. Osawa, O. Josimovic-Alasevic, E. Rüde, T. Diamantstein: Soluble interleukin-2 receptors are released by long term-cultured insulin-specific T cells transiently after contact with antigen. J. Immunol. 138 (1987) 192-196
77. Rolfe, M. W., T.J. Standiford, S. L. Kunkel et al: Interleukin-1 receptor antagonist expression in sarcoidosis. Am. Rev. Respir. Dis. 148 (1993) 1378-1384
78. Scadding, J.: Sarcoidosis. Eyre & Spottiswoode, London 1967
79. Scharkoff, T.: Epidemiologie der Sarkoidose. Pneumologie 47 (1993) 588-592
80. Schlegel, U.: Neurosarkoidose: Diagnostik und Therapie. Fortschr. Neurol. Psychiat. 55 (1987) 1-15
81. Schmitt, M., H. Wirtz: Sarkoidose der Lunge: Klinischer Verlauf und entzündliche Aktivität. Pneumologie 49 (1995) 226-232
82. Schoenberger, C. I., B. R. Line, B. A. Keogh, G. W. Hunninghake, R. G. Crystal: Lung inflammation in sarcoidosis: comparison of serum angiotensin-converting enzyme levels with bronchoalveolar lavage and gallium-67 scanning assessment of T lymphocyte alveolitis. Thorax 37 (1982) 19-25
83. Siltzbach, L.: Sarcoidosis: Clinical features and management. Med. Clin. N. Amer. 51 (1967) 483-502
84. Silverman, K., G. Hutchius, B. Bulkley: Cardiac sarcoid: a clinicopathological study of 84 unselected patients with systemic sarcoidosis. Chest 58 (1978) 1204-1211
85. Sprince, N. L., H. Kazemi: Beryllium disease. In: Fanburg, B. (ed.): Sarcoidosis and other granulomatous diseases of the lung. Dekker, Basel 1983, S. 453-468
86. Steffen, M., J. Petersen, M. Oldigs et al.: Increased secretion of tumor necrosis factor-alpha, interleukin-1-beta, and interleukin-6 by alveolar macrophages from patients with sarcoidosis. Chest 91 (1993) 939-949
87. Strausz, J., D. Männel, S. Pfeifer, A. Borkowski, R. Ferlinz, J. Müller-Quernheim: Spontaneous monokine release by alveolar macrophages in chronic sarcoidosis. Int. Archs. Allergy appl. Immun. 96 (1991) 68-75
88. Strausz, J., J. Müller-Quernheim, R. Ferlinz: Serumspiegel des sezernierten Interleukin-2 Rezeptor als ein Aktivitätsparameter der Sarkoidose. Dtsch. med. Wschr. 114 (1989) 744-749
89. Striz, I., J. Wang, H. Teschler, C. Sorg, U. Costabel: Phenotypic markers of alveolar macrophage maturation in pulmonary sarcoidosis. Lung 171 (1993) 293-303
90. Suzuki, T., T. Kanda, S. Kubota, S. Imai, K. Murata: Holter monitoring as a noninvasive indicator of cardiac involvement in sarcoidosis. Chest 106 (1994) 1021-1024
91. Tamura, N., K. J. Holrody, T. Banks, M. Kirby, H. Okayana, R. G. Crystal: Diversity in junctional sequences associated with the common Vγ9 and Vδ2 gene segments in the normal blood and lung compared with limited diversity in a granulomatous disease. J. Exp. Med. 172 (1990) 169-181
92. Tamura, N., D. Moller, B. Balbi, R. Crystal: Preferential usage of the T-cell antigen receptor beta-chain constant region C beta 1 element by lung T-lymphocytes of patients with pulmonary sarcoidosis. Am. Rev. Respir. Dis. 143 (1991) 635-639
93. Teirstein, A. S., M. Lesser: Worldwide distribution and epidemiology of sarcoidosis. In: Fanburg, B. (ed.): Sarcoidosis and other granulomatous diseases of the lung. Dekker, Basel 1983, S. 232-334
94. The BAL Cooperative Group Steering Committee: Bronchoalveolar lavage constitutents in healthy individuals, idiopathic pulmonary fibrosis, and selected comparison groups. Am. Rev. Respir. Dis. 141 (1990) S169-S201
95. Toossi, Z., J. R. Sedor, J. P. Lapurga, R. J. Ondash, J. J. Ellner: Expression of functional interleukin 2 receptors by peripheral blood monocytes from patients with active pulmonary tuberculosis. J. Clin. Invest. 85 (1990) 1777-1784
96. Tung, K. S. K., E. Umland, P. Matzner et al.: Soluble serum interleukin-2 receptor level in leprosy patients. Clin. exp. Immunol. 68 (1987) 10-17
97. Venet, A., A. J. Hance, C. Saltini, B. W. S. Robinson, R. G. Crystal: Enhanced alveolar macrophage-mediated antigen-induced T lymphocyte proliferation in sarcoidosis. J. Clin. Invest. 75 (1985) 293-301
98. Vestbo, J., K. Viskum: Respiratory symptoms at presentation and long-term vital prognosis in patients with pulmonary sarcoidosis. Sarcoidosis 11 (1994) 123-125
99. Viskum, K., J. Vestbo: Vital prognosis in intrathoracic sarcoidosis with special reference to pulmonary function and radiological stage. Eur. Respir. J. 6 (1993) 349-353
100. Ward, K., C. O'Connor, C. Odlum, M. X. Fitzgerald: Pognostic value of bronchoalveolar lavage in sarcoidosis: The critical influence of disease presentation. Thorax 44 (1989) 6-12
101. Yamamoto, M., O. P. Sharma: The 1991 descriptive definition of sarcoidosis. Sarcoidosis 9 (1991) s33-s34