In vivo survival and organ uptake of loaded carrier rat erythrocytes

Journal of Biochemistry

Volumn 120, Issue 2, 1996, Pages 286-291

  Alvarez, F Javier ^a   Herráez, Angel ^a   Murciano, Juan C ^a   Jordán, José A ^a   Díez, José C ^a   Tejedor, M Cristina ^a  

^a UNIVERSITY OF ALCALÁ   (Spain)

Author keywords

Carrier erythrocytes; Cell targeting; Encapsulated carbonic anhydrase; Organ uptake; Sustained release

Indexed keywords

CARBONATE DEHYDRATASE; DRUG CARRIER; IODINE 125;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BIOCHEMISTRY; CELL SURVIVAL; CIRCULATION; CONTROLLED STUDY; CYTOLYSIS; DIALYSIS; DRUG TISSUE LEVEL; ENCAPSULATION; ERYTHROCYTE; HALF LIFE TIME; LIVER METABOLISM; NONHUMAN; PHARMACOLOGY; RAT; SPLEEN;

ANIMALIA;

EID: 0029683261     PISSN: 0021924X     EISSN: None     Source Type: Journal    
DOI: 10.1093/oxfordjournals.jbchem.a021411     Document Type: Article

References (25)

1. Gupta, P.K. (1990) Drug targeting in cancer chemotherapy: A clinical perspective. J. Pharm. Sci. 79, 949-962
2. DeLoach, J.R. and Droleskey, R.E. (1986) Preparation of ovine carrier erythrocytes: Their action and survival. Comp. Biochem. Physiol. A 84, 441-445
3. Zolla, L., Lupidi, G., Marcheggiani, M., Falcioni, G., and Brunori, M. (1990) Encapsulation of proteins into human erythrocytes: A kinetic investigation. Biochim. Biophys. Acta 1024, 5-9
4. De Flora, A., Zocchi, E., Guida, L., Polvani, C., and Benatti, U. (1988) Conversion of encapsulated 5-fluoro-2′-deoxyuridine 5′-monophosphate to the antineoplastic drug 5-fluoro-2′-deoxy-uridine in human erythrocytes. Proc. Natl. Acad. Sci. USA 85, 3145-3149
5. Magnani, M., Serafini, G., and Stocchi, V. (1988) Hexokinase type I multiplicity in human erythrocytes. Biochem. J. 254, 617-620
6. Rossi, L., Bianchi, M., Fraternale, A., and Magnani, M. (1992) Normalization of hyperglycemia in diabetic mice by enzyme-loaded erythrocytes. Adv. Exp. Med. Biol. 326, 183-188
7. Tonetti, M., Polvani, C., Zocchi, E., Guida, L., Benatti, U., Biassoni, P., Romei, F., Guglielmi, A., Aschele, C., Sobrero, A., and De Flora, A. (1991) Liver targeting of autologous erythrocytes loaded with doxorubicin. Eur. J. Cancer 27, 947-948
8. DeLoach, J.R. and Droleskey, R.E. (1986) Survival of murine carrier erythrocytes injected via peritoneum. Comp. Biochem. Physiol. A 84, 447-450
9. DeLoach, J.R., Andrews, K., and Sheffield, C.L. (1988) Encapsulation of interleukin-2 in murine erythrocytes and subsequent deposition in mice receiving a subcutaneous injection. Biotechnol. Appl. Biochem. 10, 183-190
10. DeLoach, J.R., Andrews, K., Satterfield, W., and Keeling, M. (1990) Intraperitoneal administration of carrier erythocytes in dogs: An improved method for delivery of L-asparaginase. Biotechnol. Appl. Biochem. 12, 331-335
11. Pitt, E., Johnson, C.M., Lewis, D.A., Jenner, D.A., and Offord, R.E. (1983) Encapsulation of drugs in intact erythrocytes and intravenous delivery system. Biochem. Pharmacol. 32, 3359-3368
12. Benatti, U., Zocchi, E., Tonetti, M., Guida, L., Polvani, C., and De Flora, A. (1989) Enhanced antitumor activity of adriamycin by encapsulation in mouse erythrocytes targeted to liver and lungs. Pharmacol. Res. 21, 27-33
13. Zocchi, E., Tonetti, M., Polvani, C., Guida, L., Benatti, U., and De Flora, A. (1988) In vivo liver and lung targeting of adriamycin encapsulated in glutaraldehyde-treated murine erythrocytes. Biotechnol. Appl. Biochem. 10, 555-562
14. Chiarantini, L., Antonelli, A., Serafini, G., Fraternale, A., and Magnani, M. (1994) In vivo survival and in vitro phagocytosis of engineered erythrocytes. Adv. Biosci. 92, 83-91
15. Ropars, C., Teisseire, B.P., Villereal, M.C., Bailleul, C., Chassaigne, M., and Nicolau, C. (1987) Engineered erythrocytes with high peripheral release of oxygen in Biotechnology in Clinical Medicine (Albertini, A., Lenfant, C., and Paoletti, R., eds.) pp. 295-302, Raven Press, New York
16. Tejedor, M.C., Alvarez, C.E., Alvarez, F.J., Herráez, A., and Luque, J. (1994) Comparative encapsulation at different hypotonic pressures in human and rat erythrocytes. Adv. Biosci. 92, 73-82
17. Alvarez, F.J., Herráez, A., Tejedor, M.C., and Díez, J.C. (1996) In vitro behaviour of rat and human erythrocytes upon hypotonic dialysis encapsulation of substances. Biotechnol. Appl. Biochem. 23, 173-179
18. Alvarez, F.J., Herráez, A., and Tejedor, M.C. (1996) Fluorescence analysis of carrier rat and human erythrocytes loaded with FITC-dextran. Cytometry 24, 181-189
19. Pérez, M.T., Alvarez, F.J., García-Pérez, A.I., Lucas, L., Tejedor, M.C., and Sancho, P. (1996) Heterogeneity of hypotonically loaded rat erythrocyte populations as detected by counter-current distribution in aqueus polymer two-phase systems. J. Chromatogr. B 677, 45-51
20. Sly, W.S., Hewett-Emmett, D., Whyte, M.P., Yu, W.Y., and Tashian, R.E. (1983) Carbonic anhydrase II deficiency identified as the primary defect in the autosomal recessive syndrome of osteopetrosis with renal tubular acidosis and cerebral calcification. Proc. Natl. Acad. Sci. USA 80, 2752-2756
21. Morrison, M., Michaels, A.W., Phillips, D.R., and Choi, S. (1974) Life span of erythrocyte membrane protein. Nature 248, 763 764, 789
22. Zocchi, E., Guida, L., Benatti, U., Canepa, M., Borgiani, L., Zanin, T., and De Flora, A. (1987) Hepatic or splenic targeting of carrier erythrocytes: A murine model. Biotechnol. Appl. Biochem. 9, 423-434
23. Chiarantini, L., Johnson, J., and DeLoach, J.R. (1991) Optimized recirculation survival of mouse carrier erythrocytes. Blood Cells 17, 607-617
24. Tonetti, M., Astroff, B., Satterfield, W., De Flora, A., Benatti, U., and DeLoach, J.R. (1990) Construction and characterization of adriamicin-loaded canine red blood cells as a potential slow delivery system. Biotechnol. Appl. Biochem. 12, 621-629
25. Tonetti, M., Bartolini, A., Sobrero, A., Guglielmi, A., Felletti, R., Gasparini, A., Benatti, U., and De Flora, A. (1994) Organ distribution of glutaraldehyde treated erythrocytes in patients with hepatic metastases. Adv. Biosci. 92, 169-176