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Volumn 120, Issue 2, 1996, Pages 433-444

Novel purification and detailed characterization of perlecan isolated from the Engelbreth-Holm-Swarm tumor for use in an animal model of fibrillar Aβ amyloid persistence in brain

Author keywords

Alzheimer's disease; EHS tumor; Heparan sulfate; Perlecan; Proteoglycans

Indexed keywords

AMYLOID BETA PROTEIN; ANTIBODY; CESIUM CHLORIDE; COLLAGEN TYPE 4; CORE PROTEIN; FIBRONECTIN; HEPARIN LYASE; LAMININ; NITROUS ACID; PERLECAN; PROTEOGLYCAN; PROTEOHEPARAN SULFATE;

EID: 0029682839     PISSN: 0021924X     EISSN: None     Source Type: Journal    
DOI: 10.1093/oxfordjournals.jbchem.a021430     Document Type: Article
Times cited : (20)

References (61)
  • 2
    • 0023664409 scopus 로고
    • Multiple forms of heparan sulfate proteoglycans in Engelbreth-Holm-Swarm mouse tumor. the occurrence of high density forms bearing both heparan sulfate and chondroitin sulfate side chains
    • Kato, M., Koike, Y., Ito, Y., Suzuki, S., and Kimata, K. (1987) Multiple forms of heparan sulfate proteoglycans in Engelbreth-Holm-Swarm mouse tumor. The occurrence of high density forms bearing both heparan sulfate and chondroitin sulfate side chains. J. Biol. Chem. 262, 7180-7188
    • (1987) J. Biol. Chem. , vol.262 , pp. 7180-7188
    • Kato, M.1    Koike, Y.2    Ito, Y.3    Suzuki, S.4    Kimata, K.5
  • 3
    • 0025705858 scopus 로고
    • Syndecan, a developmentally regulated cell surface proteoglycan that binds extracellular matrix and growth factors
    • Bernfield, M. and Sanderson, R. (1990) Syndecan, a developmentally regulated cell surface proteoglycan that binds extracellular matrix and growth factors. Phil. Trans. R. Soc. Lond. Biol. 327, 171-186
    • (1990) Phil. Trans. R. Soc. Lond. Biol. , vol.327 , pp. 171-186
    • Bernfield, M.1    Sanderson, R.2
  • 4
    • 0022050963 scopus 로고
    • Immunological characterization of basement membrane types of heparan sulfate proteoglycan
    • Dziadek, M., Fujiwara, S., Paulsson, M., and Timpl, R. (1985) Immunological characterization of basement membrane types of heparan sulfate proteoglycan. EMBO J. 4, 905-912
    • (1985) EMBO J. , vol.4 , pp. 905-912
    • Dziadek, M.1    Fujiwara, S.2    Paulsson, M.3    Timpl, R.4
  • 5
    • 0023693333 scopus 로고
    • Basement membrane proteoglycan in various tissues: Characterization using monoclonal antibodies to the Engelbreth-Holm-Swarm mouse tumor low density heparan sulfate proteoglycan
    • Kato, M., Koike, Y., Suzuki, S., and Kimata, K. (1988) Basement membrane proteoglycan in various tissues: Characterization using monoclonal antibodies to the Engelbreth-Holm-Swarm mouse tumor low density heparan sulfate proteoglycan. J. Cell Biol. 106, 2203-2210
    • (1988) J. Cell Biol. , vol.106 , pp. 2203-2210
    • Kato, M.1    Koike, Y.2    Suzuki, S.3    Kimata, K.4
  • 6
    • 0028158005 scopus 로고
    • Widespread expression of perlecan proteoglycan in basement membranes and extracellular matrices of human tissues as detected by a novel monoclonal antibody against domain III and by in situ hybridization
    • Murdoch, A.D., Liu, B., Schwarting, R., Tuan, R.S., and Iozzo, R.V. (1994) Widespread expression of perlecan proteoglycan in basement membranes and extracellular matrices of human tissues as detected by a novel monoclonal antibody against domain III and by in situ hybridization. J. Histochem. Cytochem. 42, 239-249
    • (1994) J. Histochem. Cytochem. , vol.42 , pp. 239-249
    • Murdoch, A.D.1    Liu, B.2    Schwarting, R.3    Tuan, R.S.4    Iozzo, R.V.5
  • 7
    • 0026758187 scopus 로고
    • Primary structure of the human heparan sulfate proteoglycan from basement membrane (HSPG2/perlecan). A chimeric molecule with multiple domains homologous to the low density lipoprotein receptor, laminin, neural cell adhesion molecules, and epidermal growth factor
    • Murdoch, A., Dodge, G., Cohen, I., Tuan, R., and Iozzo, R. (1992) Primary structure of the human heparan sulfate proteoglycan from basement membrane (HSPG2/perlecan). A chimeric molecule with multiple domains homologous to the low density lipoprotein receptor, laminin, neural cell adhesion molecules, and epidermal growth factor. J. Biol. Chem. 267, 8544-8557
    • (1992) J. Biol. Chem. , vol.267 , pp. 8544-8557
    • Murdoch, A.1    Dodge, G.2    Cohen, I.3    Tuan, R.4    Iozzo, R.5
  • 8
    • 0026500541 scopus 로고
    • Human basement membrane heparan sulfate proteoglycan core protein: A 467-kD protein containing multiple domains resembling elements of the low density lipoprotein receptor, laminin, neural cell adhesion molecules, and epidermal growth factor
    • Kallunki, P. and Tryggvason, K. (1992) Human basement membrane heparan sulfate proteoglycan core protein: A 467-kD protein containing multiple domains resembling elements of the low density lipoprotein receptor, laminin, neural cell adhesion molecules, and epidermal growth factor. J. Cell Biol. 116, 559-571
    • (1992) J. Cell Biol. , vol.116 , pp. 559-571
    • Kallunki, P.1    Tryggvason, K.2
  • 9
    • 0026317977 scopus 로고
    • The complete sequence of perlecan, a basement membrane heparan sulfate proteoglycan reveals extensive similarity with laminin A chain, low density lipoprotein-receptor, and the neural cell adhesion molecule
    • Noonan, D.M., Fulle, A., Valente, P., Cai, S., Horigan, E., Sasaki, M., Yamada, Y., and Hassell, J.R. (1991) The complete sequence of perlecan, a basement membrane heparan sulfate proteoglycan reveals extensive similarity with laminin A chain, low density lipoprotein-receptor, and the neural cell adhesion molecule. J. Biol. Chem. 266, 22939-22947
    • (1991) J. Biol. Chem. , vol.266 , pp. 22939-22947
    • Noonan, D.M.1    Fulle, A.2    Valente, P.3    Cai, S.4    Horigan, E.5    Sasaki, M.6    Yamada, Y.7    Hassell, J.R.8
  • 10
    • 0023942763 scopus 로고
    • Structural characterization of heparan sulfate proteoglycan subclasses isolated from bovine aortic endothelial cell cultures
    • Kinsella, M.G. and Wight, T.N. (1988) Structural characterization of heparan sulfate proteoglycan subclasses isolated from bovine aortic endothelial cell cultures. Biochemistry 27, 2136-2144
    • (1988) Biochemistry , vol.27 , pp. 2136-2144
    • Kinsella, M.G.1    Wight, T.N.2
  • 11
    • 0024593482 scopus 로고
    • Characterization of the major heparan sulfate proteoglycan secreted by bovine aortic endothelial cells in culture
    • Saku, T. and Furthmayr, H. (1989) Characterization of the major heparan sulfate proteoglycan secreted by bovine aortic endothelial cells in culture. J. Biol. Chem. 264, 3514-3523
    • (1989) J. Biol. Chem. , vol.264 , pp. 3514-3523
    • Saku, T.1    Furthmayr, H.2
  • 12
    • 0027441601 scopus 로고
    • Distribution and origin of the basement membrane component perlecan in rat liver and primary hepatocyte culture
    • Rescan, P.Y., Loreal, O., Hassell, J.R., Yamada, Y., Guillouzo, A., and Clement, B. (1993) Distribution and origin of the basement membrane component perlecan in rat liver and primary hepatocyte culture. Am. J. Pathol. 142, 199-208
    • (1993) Am. J. Pathol. , vol.142 , pp. 199-208
    • Rescan, P.Y.1    Loreal, O.2    Hassell, J.R.3    Yamada, Y.4    Guillouzo, A.5    Clement, B.6
  • 13
    • 0028357197 scopus 로고
    • Smooth muscle cell expression of extracellular matrix genes after arterial injury
    • Nikkari, S.T., Jarvelainen, H.T., Wight, T.N., Ferguson, M., and Clowes, A.W. (1994) Smooth muscle cell expression of extracellular matrix genes after arterial injury. Am. J. Pathol. 144, 1348-1356
    • (1994) Am. J. Pathol. , vol.144 , pp. 1348-1356
    • Nikkari, S.T.1    Jarvelainen, H.T.2    Wight, T.N.3    Ferguson, M.4    Clowes, A.W.5
  • 14
    • 0024830822 scopus 로고
    • Matrix-associated heparan sulfate proteoglycan: Core protein-specific monoclonal antibodies decorate the pericellular matrix of connective tissue cells and the stromal side of basement membranes
    • Heremans, S., Van der Schueren, B., DeCock, B., Paulsson, M., Cassiman, J., Van den Berghe, H., and David, G. (1989) Matrix-associated heparan sulfate proteoglycan: Core protein-specific monoclonal antibodies decorate the pericellular matrix of connective tissue cells and the stromal side of basement membranes. J. Cell Biol. 109, 3199-3211
    • (1989) J. Cell Biol. , vol.109 , pp. 3199-3211
    • Heremans, S.1    Van der Schueren, B.2    Decock, B.3    Paulsson, M.4    Cassiman, J.5    Van den Berghe, H.6    David, G.7
  • 15
    • 0028242028 scopus 로고
    • Specific stimulation of basal lamina heparan sulfate proteoglycan in mouse uterine epithelium by Matrigel and by transforming growth factor-beta 1
    • Morris, J.E., Gaza, G., and Potter, S.W. (1994) Specific stimulation of basal lamina heparan sulfate proteoglycan in mouse uterine epithelium by Matrigel and by transforming growth factor-beta 1. In Vitro Cell Dev. Biol. 30, 120-128
    • (1994) In Vitro Cell Dev. Biol. , vol.30 , pp. 120-128
    • Morris, J.E.1    Gaza, G.2    Potter, S.W.3
  • 18
    • 0028818528 scopus 로고
    • Expression of the basement membrane heparan sulfate proteoglycan (perlecan) in human synovium and in cultured human synovial cells
    • Dodge, G.R., Boesler, E.W., and Jimenez, S.A. (1995) Expression of the basement membrane heparan sulfate proteoglycan (perlecan) in human synovium and in cultured human synovial cells. Lab. Invest. 73, 649-657
    • (1995) Lab. Invest. , vol.73 , pp. 649-657
    • Dodge, G.R.1    Boesler, E.W.2    Jimenez, S.A.3
  • 19
    • 0028939114 scopus 로고
    • The proteoglycan perlecan is expressed in the erythleukemia cell line K562 and is upregulated by sodium butyrate and phorbol ester
    • Grässel, S., Cohen, I.R., Murdoch, A.D., Eichstetter, I., and Iozzo, R.V. (1995) The proteoglycan perlecan is expressed in the erythleukemia cell line K562 and is upregulated by sodium butyrate and phorbol ester. Mol. Cell Biochem. 145, 61-68
    • (1995) Mol. Cell Biochem. , vol.145 , pp. 61-68
    • Grässel, S.1    Cohen, I.R.2    Murdoch, A.D.3    Eichstetter, I.4    Iozzo, R.V.5
  • 21
    • 0027449937 scopus 로고
    • Myoepithelial and basement membrane antigens in benign and malignant human breast tumors
    • Guelstein, V.I., Tchypysheva, T.A., Ermilova, V.D., and Ljubimov, A.V. (1993) Myoepithelial and basement membrane antigens in benign and malignant human breast tumors. Int. J. Cancer 53, 269-277
    • (1993) Int. J. Cancer , vol.53 , pp. 269-277
    • Guelstein, V.I.1    Tchypysheva, T.A.2    Ermilova, V.D.3    Ljubimov, A.V.4
  • 22
    • 0027902874 scopus 로고
    • Potential markers (enzymes, proteoglycans) for human liver tumors
    • Kovalsky, I., Schaff, Z., and Jeney, A. (1993) Potential markers (enzymes, proteoglycans) for human liver tumors. Acta Biomed. Ateneo Parmense 64, 157-163
    • (1993) Acta Biomed. Ateneo Parmense , vol.64 , pp. 157-163
    • Kovalsky, I.1    Schaff, Z.2    Jeney, A.3
  • 23
    • 0027268021 scopus 로고
    • Perlecan gene expression precedes laminin gene expression during differentiation of F9 embryonal carcinoma cells
    • Chakravarti, S., Hassell, J.R., and Phillips, S. (1993) Perlecan gene expression precedes laminin gene expression during differentiation of F9 embryonal carcinoma cells. Dev. Dyn. 197, 107-114
    • (1993) Dev. Dyn. , vol.197 , pp. 107-114
    • Chakravarti, S.1    Hassell, J.R.2    Phillips, S.3
  • 24
    • 0028101047 scopus 로고
    • Characterization of proteoglycans synthesized by murine embryonal carcinoma cells (P19) reveals increased expression of perlecan (heparan sulfate proteoglycan) during neuronal differentiation
    • Sekiguchi, R.T., Potter-Perigo, S., Braun, K., Miller, J., Ngo, C., Fukuchi, K., Wight, T.N., Kimata, K., and Snow, A.D. (1994) Characterization of proteoglycans synthesized by murine embryonal carcinoma cells (P19) reveals increased expression of perlecan (heparan sulfate proteoglycan) during neuronal differentiation. J. Neurosci. Res. 38, 670-686
    • (1994) J. Neurosci. Res. , vol.38 , pp. 670-686
    • Sekiguchi, R.T.1    Potter-Perigo, S.2    Braun, K.3    Miller, J.4    Ngo, C.5    Fukuchi, K.6    Wight, T.N.7    Kimata, K.8    Snow, A.D.9
  • 25
    • 0024387388 scopus 로고
    • Proteoglycans in the pathogenesis of Alzheimer's disease
    • Snow, A.D. and Wight, T.N. (1989) Proteoglycans in the pathogenesis of Alzheimer's disease. Neurobiol. Aging 10, 481-497
    • (1989) Neurobiol. Aging , vol.10 , pp. 481-497
    • Snow, A.D.1    Wight, T.N.2
  • 26
    • 0029047722 scopus 로고
    • Differential binding of vascular cell-derived proteoglycans (perlecan, biglycan, decorin and versican) to the beta-amyloid protein of Alzheimer's disease
    • Snow, A.D., Kinsella, M.G., Parks, E., Sekiguchi, R.T., Miller, J.D., Kimata, K., and Wight, T.N. (1995) Differential binding of vascular cell-derived proteoglycans (perlecan, biglycan, decorin and versican) to the beta-amyloid protein of Alzheimer's disease. Arch. Biochem. Biophys. 320, 84-95
    • (1995) Arch. Biochem. Biophys. , vol.320 , pp. 84-95
    • Snow, A.D.1    Kinsella, M.G.2    Parks, E.3    Sekiguchi, R.T.4    Miller, J.D.5    Kimata, K.6    Wight, T.N.7
  • 27
    • 0026673537 scopus 로고
    • Effect of sulfate ions on Alzheimer β/A4 assemblies: Implications for amyloid fibril-proteoglyean interactions
    • Fraser, P.E., Nguyen, J.T., Chin, D.T., and Kirschner, D.A. (1992) Effect of sulfate ions on Alzheimer β/A4 assemblies: Implications for amyloid fibril-proteoglyean interactions. J. Neurochem. 59, 1531-1540
    • (1992) J. Neurochem. , vol.59 , pp. 1531-1540
    • Fraser, P.E.1    Nguyen, J.T.2    Chin, D.T.3    Kirschner, D.A.4
  • 28
    • 85018902762 scopus 로고    scopus 로고
    • Perlecan binds to both beta-amyloid protein (Aβ) 1-40 and 1-42, and is a potent accelerator and enhancer of Aβ fibrillogenesis
    • in press
    • Castillo, G.M. and Snow, A.D. (1996) Perlecan binds to both beta-amyloid protein (Aβ) 1-40 and 1-42, and is a potent accelerator and enhancer of Aβ fibrillogenesis. Neurobiol. Aging Abstract, in press
    • (1996) Neurobiol. Aging Abstract
    • Castillo, G.M.1    Snow, A.D.2
  • 29
  • 30
    • 0028082136 scopus 로고
    • An important role of heparan sulfate proteoglycan (perlecan) in a model system for the deposition and persistence of fibrillar Aβ amyloid in rat brain
    • Snow, A.D., Sekiguchi, R., Nochlin, D., Fraser, P., Kimata, K., Mitzutani, A., Arai, M., Schreier, W.A., and Morgan, D.G. (1994) An important role of heparan sulfate proteoglycan (perlecan) in a model system for the deposition and persistence of fibrillar Aβ amyloid in rat brain. Neuron 12, 219-234
    • (1994) Neuron , vol.12 , pp. 219-234
    • Snow, A.D.1    Sekiguchi, R.2    Nochlin, D.3    Fraser, P.4    Kimata, K.5    Mitzutani, A.6    Arai, M.7    Schreier, W.A.8    Morgan, D.G.9
  • 31
    • 0345124322 scopus 로고
    • Further studies implicating the importance of perlecan (a specific heparan sulfate proteoglycan) in an animal model of fibrillar Aβ amyloid deposition in vivo: Comparison of Aβ (1-42) versus Aβ (1-40)
    • abstract
    • Snow, A.D., Cummings, J.A., Ngo, C.T., Yang, W., Nochlin, D., Rimvall, K., Sheardown, M.J., and Judge, M. (1995) Further studies implicating the importance of perlecan (a specific heparan sulfate proteoglycan) in an animal model of fibrillar Aβ amyloid deposition in vivo: Comparison of Aβ (1-42) versus Aβ (1-40). Soc. Neurosci. Abst. 21, 1282, abstract
    • (1995) Soc. Neurosci. Abst. , vol.21 , pp. 1282
    • Snow, A.D.1    Cummings, J.A.2    Ngo, C.T.3    Yang, W.4    Nochlin, D.5    Rimvall, K.6    Sheardown, M.J.7    Judge, M.8
  • 32
    • 0026703151 scopus 로고
    • Basement-membrane heparan sulfate proteoglycan binds to laminin by its heparan sulfate chains and to nidogen by sites in the protein core
    • Battaglia, C., Mayer, U., Aumailley, M., and Timpl, R. (1992) Basement-membrane heparan sulfate proteoglycan binds to laminin by its heparan sulfate chains and to nidogen by sites in the protein core. Eur. J. Biochem. 208, 359-366
    • (1992) Eur. J. Biochem. , vol.208 , pp. 359-366
    • Battaglia, C.1    Mayer, U.2    Aumailley, M.3    Timpl, R.4
  • 34
    • 0023157437 scopus 로고
    • Domain structure of the basement membrane heparan sulfate proteoglycan
    • Ledbetter, S.R., Fisher, L.W., and Hassell, J.R. (1987) Domain structure of the basement membrane heparan sulfate proteoglycan. Biochemistry 26, 988-995
    • (1987) Biochemistry , vol.26 , pp. 988-995
    • Ledbetter, S.R.1    Fisher, L.W.2    Hassell, J.R.3
  • 35
    • 0023660965 scopus 로고
    • Structure of low density heparan sulfate proteoglycan isolated from a mouse tumor basement membrane
    • Paulsson, M., Yurchenco, P.D., Ruben, G.C., Engel, J., and Timpl, R. (1987) Structure of low density heparan sulfate proteoglycan isolated from a mouse tumor basement membrane. J. Mol. Biol. 197, 297-313
    • (1987) J. Mol. Biol. , vol.197 , pp. 297-313
    • Paulsson, M.1    Yurchenco, P.D.2    Ruben, G.C.3    Engel, J.4    Timpl, R.5
  • 36
    • 0021151003 scopus 로고
    • Structure and interaction of heparan sulfate proteoglycans from a mouse tumor basement membrane
    • Fujiwara, S., Wiedemann, H., Timpl, R., Lustig, A., and Engel, J. (1984) Structure and interaction of heparan sulfate proteoglycans from a mouse tumor basement membrane. Eur. J. Biochem. 143, 145-157
    • (1984) Eur. J. Biochem. , vol.143 , pp. 145-157
    • Fujiwara, S.1    Wiedemann, H.2    Timpl, R.3    Lustig, A.4    Engel, J.5
  • 37
    • 0023085534 scopus 로고
    • Isolation and characterization of proteoglycans
    • Heinegärd, D. and Sommarin, Y. (1987) Isolation and characterization of proteoglycans. Methods Enzymol. 144, 319-372
    • (1987) Methods Enzymol. , vol.144 , pp. 319-372
    • Heinegärd, D.1    Sommarin, Y.2
  • 38
    • 0000081293 scopus 로고
    • Transplantation of a murine chondrosarcoma in mice of different inbred strains
    • Swarm, R.L. (1963) Transplantation of a murine chondrosarcoma in mice of different inbred strains. J. Natl. Cancer Inst. 31, 953-975
    • (1963) J. Natl. Cancer Inst. , vol.31 , pp. 953-975
    • Swarm, R.L.1
  • 39
    • 8044253816 scopus 로고
    • Morphologic demonstration of recurrent tumor following X irradiation. Histologic study of irradiated murine chondrosarcoma transplants
    • Swarm, R.L., Correa, J.N., Andrews, R.J., and Miller, E. (1964) Morphologic demonstration of recurrent tumor following X irradiation. Histologic study of irradiated murine chondrosarcoma transplants. J. Natl. Cancer Inst. 33, 657-672
    • (1964) J. Natl. Cancer Inst. , vol.33 , pp. 657-672
    • Swarm, R.L.1    Correa, J.N.2    Andrews, R.J.3    Miller, E.4
  • 41
    • 0014949207 scopus 로고
    • Cleavage of structural proteins during the assembly of the head of bacteriophage T4
    • Laemmli, U.K. (1970) Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227, 680-685
    • (1970) Nature , vol.227 , pp. 680-685
    • Laemmli, U.K.1
  • 42
    • 0024269377 scopus 로고
    • Alcian blue staining of proteoglycans in polyacrylamide gels using the "critical electrolyte concentration" approach
    • Wall, R. and Gyi, T. (1988) Alcian blue staining of proteoglycans in polyacrylamide gels using the "critical electrolyte concentration" approach. Anal. Biochem. 175, 298-299
    • (1988) Anal. Biochem. , vol.175 , pp. 298-299
    • Wall, R.1    Gyi, T.2
  • 43
    • 0000544299 scopus 로고
    • A simplified ultrasensitive silver stain for detecting proteins in polyacrylamide gels
    • Oakley, B.R., Kirsch, D.R., and Morris, R.N. (1980) A simplified ultrasensitive silver stain for detecting proteins in polyacrylamide gels. Anal. Biochem. 105, 361-363
    • (1980) Anal. Biochem. , vol.105 , pp. 361-363
    • Oakley, B.R.1    Kirsch, D.R.2    Morris, R.N.3
  • 44
    • 0015935891 scopus 로고
    • Biosynthesis of heparin. II. Formation of sulfamino groups
    • Lindahl, U., Bäckström, G., Janson, L., and Hallén, A. (1973) Biosynthesis of heparin. II. Formation of sulfamino groups. J. Biol. Chem. 248, 7232-7241
    • (1973) J. Biol. Chem. , vol.248 , pp. 7232-7241
    • Lindahl, U.1    Bäckström, G.2    Janson, L.3    Hallén, A.4
  • 47
    • 84907133587 scopus 로고
    • Methods for staining amyloid in tissue: A review
    • Elghetany, M.T. and Saleem, A. (1988) Methods for staining amyloid in tissue: A review. Stain Tech. 63, 201-212
    • (1988) Stain Tech. , vol.63 , pp. 201-212
    • Elghetany, M.T.1    Saleem, A.2
  • 48
    • 0023390305 scopus 로고
    • Formic acid pretreatment enhances immunostaining of cerebral and systemic amyloids
    • Kitamoto, T., Ogomori, K., Tateishi, J., and Prusiner, S.B. (1987) Formic acid pretreatment enhances immunostaining of cerebral and systemic amyloids. Lab. Invest. 57, 230-236
    • (1987) Lab. Invest. , vol.57 , pp. 230-236
    • Kitamoto, T.1    Ogomori, K.2    Tateishi, J.3    Prusiner, S.B.4
  • 49
    • 0025223441 scopus 로고
    • Early accumulation of heparan sulfate in neurons and in the beta-amyloid protein containing lesions of Alzheimer's disease and Down's syndrome
    • Snow, A.D., Mar, H., Nochlin, D., Sekiguchi, R.T., Kimata, K., Koike, Y., and Wight, T.N. (1990) Early accumulation of heparan sulfate in neurons and in the beta-amyloid protein containing lesions of Alzheimer's disease and Down's syndrome. Am. J. Pathol. 137, 1253-1270
    • (1990) Am. J. Pathol. , vol.137 , pp. 1253-1270
    • Snow, A.D.1    Mar, H.2    Nochlin, D.3    Sekiguchi, R.T.4    Kimata, K.5    Koike, Y.6    Wight, T.N.7
  • 50
    • 0027300720 scopus 로고
    • Simultaneous preparation and quantitation of proteoglycans by precipitation with Alcian blue
    • Björnson, S. (1993) Simultaneous preparation and quantitation of proteoglycans by precipitation with Alcian blue. Anal. Biochem. 210, 282-291
    • (1993) Anal. Biochem. , vol.210 , pp. 282-291
    • Björnson, S.1
  • 53
    • 0024273721 scopus 로고
    • The presence of heparan sulfate proteoglycans in the neuritic plaques and congophilic angiopathy of Alzheimer's disease
    • Snow, A.D., Mar, H., Nochlin, D., Kimata, K., Kato, M., Suzuki, S., Hassell, J., and Wight, T.N. (1988) The presence of heparan sulfate proteoglycans in the neuritic plaques and congophilic angiopathy of Alzheimer's disease. Am. J. Pathol. 133, 456-463
    • (1988) Am. J. Pathol. , vol.133 , pp. 456-463
    • Snow, A.D.1    Mar, H.2    Nochlin, D.3    Kimata, K.4    Kato, M.5    Suzuki, S.6    Hassell, J.7    Wight, T.N.8
  • 54
    • 0026548436 scopus 로고
    • Peripheral distribution of dermatan sulfate proteoglycans (decorin) in amyloid-containing plaques and their presence in neurofibrillary tangles of Alzheimer's disease
    • Snow, A.D., Mar, H., Nochlin, D., Kresse, H., and Wight, T.N. (1992) Peripheral distribution of dermatan sulfate proteoglycans (decorin) in amyloid-containing plaques and their presence in neurofibrillary tangles of Alzheimer's disease. J. Histochem. Cytochem. 40, 105-113
    • (1992) J. Histochem. Cytochem. , vol.40 , pp. 105-113
    • Snow, A.D.1    Mar, H.2    Nochlin, D.3    Kresse, H.4    Wight, T.N.5
  • 55
    • 0027209456 scopus 로고
    • Chondroitin sulfate proteoglycans are associated with the lesions of Alzheimer's disease
    • DeWitt, D.A., Silver, J., Canning, D.R., and Perry, G. (1993) Chondroitin sulfate proteoglycans are associated with the lesions of Alzheimer's disease. Exp. Neurol. 121, 149-152
    • (1993) Exp. Neurol. , vol.121 , pp. 149-152
    • DeWitt, D.A.1    Silver, J.2    Canning, D.R.3    Perry, G.4
  • 56
    • 0029881267 scopus 로고    scopus 로고
    • Identification and immunolocalization of a new class of proteoglycan (keratan sulfate) to the neuritic plaques of Alzheimer's disease
    • Snow, A.D., Nochlin, D., Sekiguchi, R., and Carlson, S.S. (1996) Identification and immunolocalization of a new class of proteoglycan (keratan sulfate) to the neuritic plaques of Alzheimer's disease. Exp. Neurol. 138, 305-317
    • (1996) Exp. Neurol. , vol.138 , pp. 305-317
    • Snow, A.D.1    Nochlin, D.2    Sekiguchi, R.3    Carlson, S.S.4
  • 57
    • 0023128689 scopus 로고
    • Sulfated glycosaminoglycans: A common constituent of all amyloids
    • Snow, A.D., Willmer, J., and Kisilevsky, R. (1987) Sulfated glycosaminoglycans: A common constituent of all amyloids. Lab. Invest. 56, 120-123
    • (1987) Lab. Invest. , vol.56 , pp. 120-123
    • Snow, A.D.1    Willmer, J.2    Kisilevsky, R.3
  • 58
    • 0023767031 scopus 로고
    • The potential significance of sulphated glycosaminoglycans as a common constituent of all amyloids; or perhaps amyloid is not a misnomer
    • Kisilevsky, R. and Snow, A.D. (1988) The potential significance of sulphated glycosaminoglycans as a common constituent of all amyloids; or perhaps amyloid is not a misnomer. Med. Hypoth. 26, 231-236
    • (1988) Med. Hypoth. , vol.26 , pp. 231-236
    • Kisilevsky, R.1    Snow, A.D.2
  • 59
    • 0025243737 scopus 로고
    • Immunolocalization of heparan sulfate proteoglycans to prion protein amyloid plaques of Gerstmann-Straussler syndrome, Creutzfeldt-Jakob disease and scrapie
    • Snow, A.D., Wight, T.N., Nochlin, D., Koike, Y., Kimata, K., DeArmond, S.J., and Prusiner, S.B. (1990) Immunolocalization of heparan sulfate proteoglycans to prion protein amyloid plaques of Gerstmann-Straussler syndrome, Creutzfeldt-Jakob disease and scrapie. Lab. Invest. 63, 601-611
    • (1990) Lab. Invest. , vol.63 , pp. 601-611
    • Snow, A.D.1    Wight, T.N.2    Nochlin, D.3    Koike, Y.4    Kimata, K.5    DeArmond, S.J.6    Prusiner, S.B.7
  • 60
    • 8044228785 scopus 로고
    • A temporal and ultrastructural relationship between heparan sulfate proteoglycans and AA amyloid in experimental amyloidosis
    • Snow, A.D., Wight, T.N., Mar, H., Bramson, R., and Kisilevsky, R. (1991) A temporal and ultrastructural relationship between heparan sulfate proteoglycans and AA amyloid in experimental amyloidosis. J. Histochem. Cytochem. 40, 105-113
    • (1991) J. Histochem. Cytochem. , vol.40 , pp. 105-113
    • Snow, A.D.1    Wight, T.N.2    Mar, H.3    Bramson, R.4    Kisilevsky, R.5
  • 61
    • 0026688125 scopus 로고
    • Localization of the basement membrane heparan sulfate proteoglycan in islet amyloid deposits in type II diabetes mellitus
    • Young, I.D., Ailles, L., Narindrasorasak, S., Tan, R., and Kisilevsky, R. (1992) Localization of the basement membrane heparan sulfate proteoglycan in islet amyloid deposits in type II diabetes mellitus. Arch. Pathol. Lab. Med. 116, 951-954
    • (1992) Arch. Pathol. Lab. Med. , vol.116 , pp. 951-954
    • Young, I.D.1    Ailles, L.2    Narindrasorasak, S.3    Tan, R.4    Kisilevsky, R.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.