Chapter 5 Molecular Biology In Nutrition Research: Modeling Of Folate Metabolism

Advances in Food and Nutrition Research

Volumn 40, Issue C, 1996, Pages 95-106

  Lin, Bi Fong ^a   Kim, Jong Sang ^a   Hsu, Juei Chuan ^a   Osborne, Charles ^a   Lowe, Karen ^a   Garrow, Timothy ^a   Shane, Barry ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FOLIC ACID; FOLYLPOLYGLUTAMATE SYNTHASE; PEPTIDE SYNTHASE;

ANIMAL; BIOLOGICAL MODEL; GENETIC TRANSFECTION; GENETICS; HUMAN; METABOLISM; NUTRITION; REVIEW;

ANIMALS; FOLIC ACID; HUMANS; MODELS, BIOLOGICAL; NUTRITION PHYSIOLOGY; PEPTIDE SYNTHASES; TRANSFECTION;

EID: 0029680290     PISSN: 10434526     EISSN: None     Source Type: Book Series    
DOI: 10.1016/S1043-4526(08)60022-4     Document Type: Chapter

References (9)

1. Garrow T.A., Admon A., and Shane B. Expression cloning of a human cDNA encoding folylpoly-γ-glutamate synthetase and determination of its primary structure. Proc. Natl. Acad. Sci. U.S.A 89 (1992) 9151-9155
2. Garrow T.A., Brenner A., Whitehead V.M., Chen X.-N., Duncan R.G., Korenberg J.R., and Shane B. Cloning of human cDNAs encoding mitochondrial and cytosolic serine hydroxymethyltransferases and chromosomal localization. J. Biol. Chem 268 (1993) 11910-11916
3. Kim J.-S., Lowe K.E., and Shane B. Regulation of folate and one carbon metabolism in mammalian cells. 4. Role of folylpolyglutamate synthetase in antifolate metabolism and cytotoxicity. J. Biol. Chem 268 (1993) 21680-21685
4. Lin B.-F., Huang R.-F.S., and Shane B. Regulation of folate and one carbon metabolism in mammalian cells. 3. Role of mitochondrial folylpolyglutamate synthetase. J. Biol. Chem 268 (1993) 21674-21679
5. Lin B.-F., and Shane B. Expression of Escherichia coli folylpolyglutamate synthetase in the Chinese hamster ovary cell mitochondrion. J. Biol Chem 269 (1994) 9705-9713
6. Lowe K.E., Osborne C.B., Lin B.-F., Kim J.-S., Hsu J.-C., and Shane B. Regulation of folate and one carbon metabolism in mammalian cells. 2. Effect of folylpolyglutamate synthetase substrate specificity and level on folate metabolism and folylpolyglutamate specificity of metabolic cycles of one carbon metabolism. J. Biol. Chem 268 (1993) 21665-21673
7. Osborne C.B., Lowe K.E., and Shane B. Regulation of folate and one carbon metabolism in mammalian cells. 1. Folate metabolism in Chinese hamster ovary cells expressing Escherichia coli or human folylpoly-γ-glutamate synthetase activity. J. Biol. Chem 268 (1993) 21657-21664
8. Shane B. Folylpolyglutamate synthesis and role in the regulation of one carbon metabolism. Vitam. Horm. (N.Y.) 45 (1989) 263-335
9. Taylor R.T., and Hanna M.L. Folate-dependent enzymes in cultured Chinese hamster ovary cells: Folylpolyglutamate synthetase and its absence in mutants auxotrophic for glycine + adenosine + thymidine. Arch. Biochem. Biophys 181 (1977) 331-344