Analysis of T cell receptor y transcripts in right and left knee synovial fluids of patients with rheumatoid arthritis

Journal of Rheumatology

Volumn 23, Issue 7, 1996, Pages 1143-1150

  Doherty, Paul J ^a   Inman, Robert D ^a   Laxer, Ronald M ^a   Silverman, Earl D ^a   Yang, Sherry X ^a   Suurmann, Ingrid ^a   Pan, Sueihua ^a  

^a TORONTO WESTERN HOSPITAL   (Canada)

Author keywords

Clonality; Lymphocyte; Rheumatoid arthritis

Indexed keywords

COMPLEMENTARY DNA; DNA FRAGMENT; MESSENGER RNA; T LYMPHOCYTE RECEPTOR GAMMA CHAIN;

ADULT; ARTICLE; BLOOD SAMPLING; CASE REPORT; DNA SEQUENCE; GENE EXPRESSION; HUMAN; HUMAN CELL; LYMPHOCYTE CLONE; MALE; MOLECULAR CLONING; MULTIGENE FAMILY; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RHEUMATOID ARTHRITIS; RNA SEQUENCE; RNA TRANSCRIPTION; SEQUENCE ANALYSIS; SYNOVIAL FLUID; T LYMPHOCYTE;

AMINO ACID SEQUENCE; ARTHRITIS, RHEUMATOID; BASE SEQUENCE; DNA, COMPLEMENTARY; GENE EXPRESSION; HUMANS; KNEE JOINT; POLYMERASE CHAIN REACTION; RECEPTORS, ANTIGEN, T-CELL, GAMMA-DELTA; REPETITIVE SEQUENCES, NUCLEIC ACID; RNA, MESSENGER; SEQUENCE ANALYSIS, DNA; SYNOVIAL FLUID; TRANSCRIPTION, GENETIC;

EID: 0029680169     PISSN: 0315162X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (37)

1. Brenner MB, McLean J, Dialynas DP, et al: Identification of a putative second T-cell receptor. Nature 1986;322:145-9.
2. Lanier LL, Federspiel NA, Ruitenberg JJ, et al: The T cell antigen receptor complex expressed on normal peripheral blood CD4~CD8" T lymphocytes: A CDS-associated disulfide-linked y chain heterodimer. J Exp Med 79S7;165:1076-94.
3. Lefranc M-P, Rabbitts TH: Genetic organization of the human T-cell receptor y and S loci. Res Immunol /990;141:565-77.
4. Lefranc M-P, Forster A, Rabbitts TH: Rearrangement of two distinct T-cell S chain variable region genes in human DNA. Nature ;9S6;319:420-2.
5. Forster A, Huck S, Ghanem N, Lefranc M-P, Rabbitts TH: New subgroups in the human T cell rearranging Vy locus. EMBO J 1987;6:1945-50.
6. Lefranc M-P, Forster AF, Baer R, Stinson MA, Rabbitts TH:Diversity and rearrangement of the human T cell rearranging genes: Nine germ line variable genes belonging to two subgroups. Cell 1986:45:211-46.
7. Chen Z, Font MP, Loiseau P, et al: The human T-cell Vy gene locus: Cloning of new segments and study of Vy rearrangements in neoplastic T and B cells. Blood /9S8,-72:776-83.
8. Huck S, Dariavach P, Lefranc M-P: Variable region genes in the human T-cell rearranging (TRG) locus: V-J junction and homology with the mouse genes. EMBO J 1988:1:719-26.
9. Huck S, Lefranc M-P: Rearrangements to the JP1, JP and JP2 segments in the human T-cell rearranging J gene (TRGy) locus. FEES Lett 1987:224:291-6.
10. Littman DR, Newton M, Crommie D, et al: Characterization of an expressed CDS-associated Ti chain reveals Cy domain polymorphism. Nature /9S7;326:85-8.
11. Pellici PG, Subar M, Weiss A, Dalla-Favera R, Littman DR: Molecular diversity of the human T-y constant region genes. Science /987,-237:1051-5.
12. Lefranc M-P, Forster A, Rabbitts TH: Genetic polymorphism and exon changes of the constant regions of the human T-cell rearranging gene y. Proc NatlAcadSci USA 79S6;83:9596-600.
13. Buresi C, Ghanem N, Huck S, Lefranc G, Lefranc M-P: Exon duplication and triplication in the human T-cell receptor gamma constant region genes and RFLP in French, Lebanese, Tunisian, and Black African populations. Immunogenetics 1989;29:161-72.
14. Rellahan BL, Bluestone JA, Houlden BA, Cotterman MA, Matis LA: Junctional sequences influence the specificity of y/8 T cell receptors. J Exp Med /99/;173:503-6.
15. Young RA, Elliot TJ: Stress proteins, infection, and immune surveillance. Cell 1989:59:5-8.
16. Galea P, Brenzinschek R, Lipsky P, Oppenheimer-Marks N: Phenotypic characterization of CD4-/ct TCR+ and yo TCR+ T cells with a transendothelial migratory capacity. J Immunol 1994; 153:529-2.
17. Kabelitz D: Function and specificity of human y/8-positive T cells. Crit Rev Immunol 7992/11:281-303.
18. Reme T, Portier M, Frayssinoux F, et al: T cell receptor expression and activation of synovial lymphocyte subsets in patients with rheumatoid arthritis: Phenotyping of multiple synovial sites. Arthritis Rheum 7990/33:485-92.
19. Jacobs MR, Haynes BF: Increase in TCRyS T lymphocytes in synovia from rheumatoid arthritis patients with active synovitis. J Clin Immunol 1992; 12:130-8.
20. Meliconi R, Uguccioni M, D'Errico A, Cassisa A, Frizziero L, Facchini A: T-cell receptor gamma-delta positive lymphocytes in synovial membrane. BrJ Rheumatol 7992/31:59-61.
21. Brennan FM, Londei M, Jackson AM, et al: T cells expressing y8 chain receptors in rheumatoid arthritis. J Autoimmun 798S/l:319-26.
22. Chaouni I, Radal M, Simony-Lafontaine J, Combe B, Sany J, Reme T: Distribution of T-cell receptor-bearing lymphocytes in the synovial membrane from patients with rheumatoid arthritis. J Autoimmun 7992/3:737-45.
23. El-Gabalaway HS, Keillor J: Immunohistologic study of T-cell receptor o-chain expression in rheumatoid synovial membranes. Semin Arthritis Rheum /992;21:239-45.
24. Kohsaka H, Chen PP, Taniguchi A, Oilier WER, Carson DA: Divergent T cell receptor y repertoires in rheumatoid arthritis monozygotic twins. Arthritis Rheum 7995/36:213-21.
25. Olive C, Gatenby PA, Serjeantson SW: Molecular characterization of the Vy9 T cell receptor repertoire expressed in patients with rheumatoid arthritis. Eur J Immunol 7992/22:2901-6.
26. Olive C, Gatenby PA, Serjeantson SW: Evidence for oligoclonality of T cell receptor 8 chain transcripts expressed in rheumatoid arthritis patients. Eur J Immunol 7992/22:2587-93.
27. Bucht A, Soderstrom K, Hultman T, et al: T cell receptor diversity and activation markers in the V81 subset of rheumatoid synovial fluid and peripheral blood T lymphocytes. Eur J Immunol 7992/22:567-74.
28. Doherty PJ, Yang SX, Laxer R, Silverman E, Inman R, Pan S: Evidence for clonal expansion of T cell receptor VyII+ T cells in the synovial fluid of patients with arthritis. J Immunol 1992; 149:295-9.
29. Doherty PJ, Huesca-Contreras M, Dosen H-M, Pan S: Rapid amplification of complementary DNA from small amounts of unfractionated RNA. Anal Biochem /989;177:7-10.
30. Lefranc M-P, Chuchana P, Dariavach P, et al: Molecular mapping of the human T cell receptor y (TRG) genes and linkage of the variable and constant regions. Eur J Immunol / 989/19:989-94.
31. Kabat EA, Wu TT, Perry HM, Gottesman KS, Foeller C: Sequences of Proteins of Immunological Interest, Vol. 1, 5th ed. Bethesda, MD: US Department of Health and Human Services, 1991.
32. Wang AM, Doyle MV, Mark DF: Quantitation of mRNA by the polymerase chain reaction. Proc Natl Acad Sei USA 7 989/86:9717-21.
33. Fellah JS, Kerfjourn F, Charlemagne J: Evolution of T cell receptor genes. Extensive diversity of V families in the Mexican axolotl. J Immunol /994/153:4539-t5.
34. Rudikoff S, Pumphrey JG: Functional antibody lacking a variableregion disulfide bridge. Proc Natl Acad Sei USA 7 986/83:7875-8.
35. Zhang X-M, Tonnelle C, Lefranc M-P, Huck S: T cell receptor y cDNA in human fetal liver and thymus: Variable regions of y chains are restricted to Vyl or V9, due to the absence of splicing of the V10 and VII leader intron. Eur J Immunol ;994;24:571-8.
36. Hingorani R, Choi I-H, Akolkar P, et al: Clonal predominance of T cell receptors within the CD8+ CD45RO+ subset in normal human subjects. J Immunol 7993/151:5762-9.
37. Offner H, Buenafe AC, Vainiene M, et al: Where, when, and how to detect biased expression of disease-relevant V genes in rats with experimental autoimmune encephalomyelitis. J Immunol 7993/151:506-17.