메뉴 건너뛰기




Volumn 1, Issue 1, 1996, Pages 30-38

Rates of development of methotrexate resistance in heterogeneous mouse mammary tumor cell cultures

Author keywords

Drug resistance; Methotrexate; Tumor heterogeneity

Indexed keywords

ANTINEOPLASTIC ANTIMETABOLITE; DIHYDROFOLATE REDUCTASE; METHOTREXATE;

EID: 0029677308     PISSN: 13594117     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (2)

References (29)
  • 1
    • 0019941487 scopus 로고
    • Biological diversity in metastatic neoplasms: Origins and implications
    • Fidler IJ, Hart IR. Biological diversity in metastatic neoplasms: origins and implications. Science 217: 998-1003, 1982.
    • (1982) Science , vol.217 , pp. 998-1003
    • Fidler, I.J.1    Hart, I.R.2
  • 2
    • 0020371245 scopus 로고
    • On the genesis and regulation of cellular heterogeneity in malignant tumors
    • Poste G, Grieg R. On the genesis and regulation of cellular heterogeneity in malignant tumors. Invasion Metastasis 2: 137-176, 1982.
    • (1982) Invasion Metastasis , vol.2 , pp. 137-176
    • Poste, G.1    Grieg, R.2
  • 3
    • 0021242388 scopus 로고
    • Tumor heterogeneity
    • Heppner GH. Tumor heterogeneity. Cancer Res 44: 2259-2265, 1984.
    • (1984) Cancer Res , vol.44 , pp. 2259-2265
    • Heppner, G.H.1
  • 4
    • 0018957497 scopus 로고
    • Growth interaction in vivo between tumor subpopulations derived from a single mouse mammary tumor
    • Miller BE, Miller FR, Leith J, Heppner GH. Growth interaction in vivo between tumor subpopulations derived from a single mouse mammary tumor. Cancer Res 40: 3977-3981, 1980.
    • (1980) Cancer Res , vol.40 , pp. 3977-3981
    • Miller, B.E.1    Miller, F.R.2    Leith, J.3    Heppner, G.H.4
  • 5
    • 0023149068 scopus 로고
    • Growth properties of artificial heterogeneous human colon tumors
    • Leith JT, Michelson S, Faulkner LE, Bliven SF. Growth properties of artificial heterogeneous human colon tumors. Cancer Res 47: 1045-1051, 1987.
    • (1987) Cancer Res , vol.47 , pp. 1045-1051
    • Leith, J.T.1    Michelson, S.2    Faulkner, L.E.3    Bliven, S.F.4
  • 6
    • 0023750023 scopus 로고
    • Dominance of a mammary tumor subpopulation line in mixed, heterogeneous tumors
    • Miller BE, Miller FR, Wilburn D, Heppner GH. Dominance of a mammary tumor subpopulation line in mixed, heterogeneous tumors. Cancer Res 48: 5747-4753, 1988.
    • (1988) Cancer Res , vol.48 , pp. 5747-4753
    • Miller, B.E.1    Miller, F.R.2    Wilburn, D.3    Heppner, G.H.4
  • 7
    • 84936446946 scopus 로고
    • Tumor cell supopulation interactions mediated by transforming growth factor α may contribute to clonal dominance of metastatically comapetent cells in primary tumors
    • Burger MM, Sordat B, Zingernagel RM, (eds). Basel: Karger
    • Kerbel RS, Theodorescu D. Tumor cell supopulation interactions mediated by transforming growth factor α may contribute to clonal dominance of metastatically comapetent cells in primary tumors. In: Burger MM, Sordat B, Zingernagel RM, (eds). Cell to Cell Interaction, Basel: Karger, pp. 110-113, 1990.
    • (1990) Cell to Cell Interaction , pp. 110-113
    • Kerbel, R.S.1    Theodorescu, D.2
  • 8
    • 0019778506 scopus 로고
    • Tumor heterogeneity and drug sensitivity: Interactions between tumor subpopulations affecting their sensitivity to the antineoplastic agents cyclophosphamide and methotrexate
    • Miller BE, Miller FR, Heppner GH. Tumor heterogeneity and drug sensitivity: interactions between tumor subpopulations affecting their sensitivity to the antineoplastic agents cyclophosphamide and methotrexate. Cancer Res 41: 4378-4381, 1981.
    • (1981) Cancer Res , vol.41 , pp. 4378-4381
    • Miller, B.E.1    Miller, F.R.2    Heppner, G.H.3
  • 9
    • 0021733825 scopus 로고
    • Effect of cell-cell interactions on drug sensitivity and growth of drug-sensitive and -resistant tumor cells in spheroids
    • Tofilon PJ, Buckley N, Deen PF. Effect of cell-cell interactions on drug sensitivity and growth of drug-sensitive and -resistant tumor cells in spheroids. Science 226:, 862-864, 1984.
    • (1984) Science , vol.226 , pp. 862-864
    • Tofilon, P.J.1    Buckley, N.2    Deen, P.F.3
  • 10
    • 0024382120 scopus 로고
    • Therapeutic perturbations of the tumor ecosystem in reconstructed heterogeneous mouse mammary tumors
    • Miller BE, Miller FR, Heppner GH. Therapeutic perturbations of the tumor ecosystem in reconstructed heterogeneous mouse mammary tumors. Cancer Res 49: 3747-3753, 1989.
    • (1989) Cancer Res , vol.49 , pp. 3747-3753
    • Miller, B.E.1    Miller, F.R.2    Heppner, G.H.3
  • 11
    • 0026559007 scopus 로고
    • Heterogeneity of progesterone receptor content and remodeling by tamoxifen characterize subpopulations of cultured human breast cancer cells: Analysis by quantitative dual parameter flow cytometry
    • Graham ML, Smith JA, Jewett PB, Horwitz KB. Heterogeneity of progesterone receptor content and remodeling by tamoxifen characterize subpopulations of cultured human breast cancer cells: analysis by quantitative dual parameter flow cytometry. Cancer Res 52: 593-602, 1992.
    • (1992) Cancer Res , vol.52 , pp. 593-602
    • Graham, M.L.1    Smith, J.A.2    Jewett, P.B.3    Horwitz, K.B.4
  • 12
    • 0020358986 scopus 로고
    • Evolution of tumor cell heterogeneity during progressive growth of individual lung metastases
    • Poste G, Tzeng J, Doll J, Grieg R, Rieman D, Zeidman I. Evolution of tumor cell heterogeneity during progressive growth of individual lung metastases. Proc Natl Acad Sci (USA) 79: 6574-6578, 1982.
    • (1982) Proc Natl Acad Sci (USA) , vol.79 , pp. 6574-6578
    • Poste, G.1    Tzeng, J.2    Doll, J.3    Grieg, R.4    Rieman, D.5    Zeidman, I.6
  • 13
    • 0020373697 scopus 로고
    • Clonal drift of cell surface, melanogenesis, and experimental metastatic properties of in vivo selected, brain meninges-colonizing murine B16 melanoma
    • Miner KM, Kawaguchi T, Uba GW, Nicolson GL. Clonal drift of cell surface, melanogenesis, and experimental metastatic properties of in vivo selected, brain meninges-colonizing murine B16 melanoma. Cancer Res 42: 4631-4636, 1982.
    • (1982) Cancer Res , vol.42 , pp. 4631-4636
    • Miner, K.M.1    Kawaguchi, T.2    Uba, G.W.3    Nicolson, G.L.4
  • 14
    • 0023633109 scopus 로고
    • Analysis of tumor cell composition of tumors composed of paired mixtures of mammary tumor cell lines
    • Miller BE, Miller FR, Wilburn D, Heppner GH. Analysis of tumor cell composition of tumors composed of paired mixtures of mammary tumor cell lines. Br J Cancer 56:, 561-569, 1987.
    • (1987) Br J Cancer , vol.56 , pp. 561-569
    • Miller, B.E.1    Miller, F.R.2    Wilburn, D.3    Heppner, G.H.4
  • 15
    • 0024592701 scopus 로고
    • Genotypic and phenotypic evidence of clonal interactions in murine tumor cells
    • Itaya T, Judde J, Hunt B, Frost P. Genotypic and phenotypic evidence of clonal interactions in murine tumor cells. J Natl Cancer Inst 81: 664-668, 1989.
    • (1989) J Natl Cancer Inst , vol.81 , pp. 664-668
    • Itaya, T.1    Judde, J.2    Hunt, B.3    Frost, P.4
  • 17
    • 0018075053 scopus 로고
    • Heterogeneity in drug sensitivity among tumor cell subpopulations of a single mouse mammary tumor
    • Heppner GH, Dexter DL, DeNucci T, Miller FR, Calabresi P. Heterogeneity in drug sensitivity among tumor cell subpopulations of a single mouse mammary tumor. Cancer Res 38: 3758-3763, 1978.
    • (1978) Cancer Res , vol.38 , pp. 3758-3763
    • Heppner, G.H.1    Dexter, D.L.2    DeNucci, T.3    Miller, F.R.4    Calabresi, P.5
  • 18
    • 0026040389 scopus 로고
    • Tumor subpopulation interactions affecting melphalan sensitivity in palpable mouse mammary tumors
    • Miller BE, Machemer T, Lehotan M, Heppner GH. Tumor subpopulation interactions affecting melphalan sensitivity in palpable mouse mammary tumors. Cancer Res 51: 4378-4387, 1991.
    • (1991) Cancer Res , vol.51 , pp. 4378-4387
    • Miller, B.E.1    Machemer, T.2    Lehotan, M.3    Heppner, G.H.4
  • 19
    • 0020081481 scopus 로고
    • Rapid formation of poly-gamma-glutamyl derivatives of methotrexate and their association with dihydrofolate reductase as assessed by high pressure liquid chromatography in the Ehrlich ascites tumor cell in vitro
    • Fry DW, Yalowich JC, Goldman ID. Rapid formation of poly-gamma-glutamyl derivatives of methotrexate and their association with dihydrofolate reductase as assessed by high pressure liquid chromatography in the Ehrlich ascites tumor cell in vitro. J Biol Chem 257: 1890-1896, 1982.
    • (1982) J Biol Chem , vol.257 , pp. 1890-1896
    • Fry, D.W.1    Yalowich, J.C.2    Goldman, I.D.3
  • 20
    • 0026075874 scopus 로고
    • Identification of a highly glycosylated methotrexate membrane carrier in K562 human erythroleukemia cells up-regulated for tetrahydrofolate cofactor and methotrexate transport
    • Matherly LH, Czajkowski CA, Angeles SM. Identification of a highly glycosylated methotrexate membrane carrier in K562 human erythroleukemia cells up-regulated for tetrahydrofolate cofactor and methotrexate transport. Cancer Res 51: 3420-3426, 1991.
    • (1991) Cancer Res , vol.51 , pp. 3420-3426
    • Matherly, L.H.1    Czajkowski, C.A.2    Angeles, S.M.3
  • 23
    • 0002940875 scopus 로고
    • The basis of antifolate cytotoxicity, selectivity, and metabolic transformations: Effects on utilization of endogenous and exogenous folate cofactors
    • Powis G, (ed), Oxford: Pergammon Press
    • Matherly LH, Seither RL, Goldman ID. The basis of antifolate cytotoxicity, selectivity, and metabolic transformations: effects on utilization of endogenous and exogenous folate cofactors. In: Powis G, (ed), Anticancer Drugs: Antimetabolite Metabolism and Natural Anticancer Agents, Oxford: Pergammon Press, pp. 139-177, 1994.
    • (1994) Anticancer Drugs: Antimetabolite Metabolism and Natural Anticancer Agents , pp. 139-177
    • Matherly, L.H.1    Seither, R.L.2    Goldman, I.D.3
  • 24
    • 0024444318 scopus 로고
    • Inherent resistance of human squamous carcinoma cell lines to methotrexate as a result of decreased polyglutamylation of this drug
    • Pizzorno G, Chang YM, McGuire JJ, Bertino JR. Inherent resistance of human squamous carcinoma cell lines to methotrexate as a result of decreased polyglutamylation of this drug. Cancer Res 49: 5275-5280, 1989.
    • (1989) Cancer Res , vol.49 , pp. 5275-5280
    • Pizzorno, G.1    Chang, Y.M.2    McGuire, J.J.3    Bertino, J.R.4
  • 25
    • 0025817134 scopus 로고
    • Decreased folyl-polyglutamate synthetase activity as a mechanism of methotrexate resistance in CCRF-CEM human leukemia sublines
    • McCloskey DE, McGuire JJ, Russell CA, Rowan BG, Bertino JR, Pizzorno G, Mini R. Decreased folyl-polyglutamate synthetase activity as a mechanism of methotrexate resistance in CCRF-CEM human leukemia sublines. J Biol Chem 266: 6181-6187, 1991.
    • (1991) J Biol Chem , vol.266 , pp. 6181-6187
    • McCloskey, D.E.1    McGuire, J.J.2    Russell, C.A.3    Rowan, B.G.4    Bertino, J.R.5    Pizzorno, G.6    Mini, R.7
  • 26
    • 0017644532 scopus 로고
    • Acquired methotrexate resistance in lympnoblasts resulting from altered kinetic properties of dihydrofolate reductase
    • Jackson RC, Niethammer D. Acquired methotrexate resistance in lympnoblasts resulting from altered kinetic properties of dihydrofolate reductase. Eur J Cancer 13: 567-575, 1977.
    • (1977) Eur J Cancer , vol.13 , pp. 567-575
    • Jackson, R.C.1    Niethammer, D.2
  • 27
    • 0019174166 scopus 로고
    • Methotrexate-resistant Chinese hamster ovary cells contain a dihydrofolate reductase with an altered affinity for methotrexate
    • Flintoff WF, Essani K. Methotrexate-resistant Chinese hamster ovary cells contain a dihydrofolate reductase with an altered affinity for methotrexate. Biochemistry 19: 4321-4327, 1980.
    • (1980) Biochemistry , vol.19 , pp. 4321-4327
    • Flintoff, W.F.1    Essani, K.2
  • 28
    • 0019186331 scopus 로고
    • A methotrexate insensitive variant of folate reductase present in two lines of methotrexate-resistant L5178 gamma cells
    • Goldie JH, Krystal G, Hartley D, Gudauskas G, Dedhar S. A methotrexate insensitive variant of folate reductase present in two lines of methotrexate-resistant L5178 gamma cells. Eur J Cancer 16: 1539-1546, 1980.
    • (1980) Eur J Cancer , vol.16 , pp. 1539-1546
    • Goldie, J.H.1    Krystal, G.2    Hartley, D.3    Gudauskas, G.4    Dedhar, S.5
  • 29
    • 0019817704 scopus 로고
    • Properties of an altered dihydrofolate reductase encoded by amplified genes in cultured mouse fibroblasts
    • Haber DA, Beverly SM, Kiely ML, Schimke RT. Properties of an altered dihydrofolate reductase encoded by amplified genes in cultured mouse fibroblasts. J Biol Chem 256: 9501-9510, 1981.
    • (1981) J Biol Chem , vol.256 , pp. 9501-9510
    • Haber, D.A.1    Beverly, S.M.2    Kiely, M.L.3    Schimke, R.T.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.