-
1
-
-
0019941487
-
Biological diversity in metastatic neoplasms: Origins and implications
-
Fidler IJ, Hart IR. Biological diversity in metastatic neoplasms: origins and implications. Science 217: 998-1003, 1982.
-
(1982)
Science
, vol.217
, pp. 998-1003
-
-
Fidler, I.J.1
Hart, I.R.2
-
2
-
-
0020371245
-
On the genesis and regulation of cellular heterogeneity in malignant tumors
-
Poste G, Grieg R. On the genesis and regulation of cellular heterogeneity in malignant tumors. Invasion Metastasis 2: 137-176, 1982.
-
(1982)
Invasion Metastasis
, vol.2
, pp. 137-176
-
-
Poste, G.1
Grieg, R.2
-
3
-
-
0021242388
-
Tumor heterogeneity
-
Heppner GH. Tumor heterogeneity. Cancer Res 44: 2259-2265, 1984.
-
(1984)
Cancer Res
, vol.44
, pp. 2259-2265
-
-
Heppner, G.H.1
-
4
-
-
0018957497
-
Growth interaction in vivo between tumor subpopulations derived from a single mouse mammary tumor
-
Miller BE, Miller FR, Leith J, Heppner GH. Growth interaction in vivo between tumor subpopulations derived from a single mouse mammary tumor. Cancer Res 40: 3977-3981, 1980.
-
(1980)
Cancer Res
, vol.40
, pp. 3977-3981
-
-
Miller, B.E.1
Miller, F.R.2
Leith, J.3
Heppner, G.H.4
-
5
-
-
0023149068
-
Growth properties of artificial heterogeneous human colon tumors
-
Leith JT, Michelson S, Faulkner LE, Bliven SF. Growth properties of artificial heterogeneous human colon tumors. Cancer Res 47: 1045-1051, 1987.
-
(1987)
Cancer Res
, vol.47
, pp. 1045-1051
-
-
Leith, J.T.1
Michelson, S.2
Faulkner, L.E.3
Bliven, S.F.4
-
6
-
-
0023750023
-
Dominance of a mammary tumor subpopulation line in mixed, heterogeneous tumors
-
Miller BE, Miller FR, Wilburn D, Heppner GH. Dominance of a mammary tumor subpopulation line in mixed, heterogeneous tumors. Cancer Res 48: 5747-4753, 1988.
-
(1988)
Cancer Res
, vol.48
, pp. 5747-4753
-
-
Miller, B.E.1
Miller, F.R.2
Wilburn, D.3
Heppner, G.H.4
-
7
-
-
84936446946
-
Tumor cell supopulation interactions mediated by transforming growth factor α may contribute to clonal dominance of metastatically comapetent cells in primary tumors
-
Burger MM, Sordat B, Zingernagel RM, (eds). Basel: Karger
-
Kerbel RS, Theodorescu D. Tumor cell supopulation interactions mediated by transforming growth factor α may contribute to clonal dominance of metastatically comapetent cells in primary tumors. In: Burger MM, Sordat B, Zingernagel RM, (eds). Cell to Cell Interaction, Basel: Karger, pp. 110-113, 1990.
-
(1990)
Cell to Cell Interaction
, pp. 110-113
-
-
Kerbel, R.S.1
Theodorescu, D.2
-
8
-
-
0019778506
-
Tumor heterogeneity and drug sensitivity: Interactions between tumor subpopulations affecting their sensitivity to the antineoplastic agents cyclophosphamide and methotrexate
-
Miller BE, Miller FR, Heppner GH. Tumor heterogeneity and drug sensitivity: interactions between tumor subpopulations affecting their sensitivity to the antineoplastic agents cyclophosphamide and methotrexate. Cancer Res 41: 4378-4381, 1981.
-
(1981)
Cancer Res
, vol.41
, pp. 4378-4381
-
-
Miller, B.E.1
Miller, F.R.2
Heppner, G.H.3
-
9
-
-
0021733825
-
Effect of cell-cell interactions on drug sensitivity and growth of drug-sensitive and -resistant tumor cells in spheroids
-
Tofilon PJ, Buckley N, Deen PF. Effect of cell-cell interactions on drug sensitivity and growth of drug-sensitive and -resistant tumor cells in spheroids. Science 226:, 862-864, 1984.
-
(1984)
Science
, vol.226
, pp. 862-864
-
-
Tofilon, P.J.1
Buckley, N.2
Deen, P.F.3
-
10
-
-
0024382120
-
Therapeutic perturbations of the tumor ecosystem in reconstructed heterogeneous mouse mammary tumors
-
Miller BE, Miller FR, Heppner GH. Therapeutic perturbations of the tumor ecosystem in reconstructed heterogeneous mouse mammary tumors. Cancer Res 49: 3747-3753, 1989.
-
(1989)
Cancer Res
, vol.49
, pp. 3747-3753
-
-
Miller, B.E.1
Miller, F.R.2
Heppner, G.H.3
-
11
-
-
0026559007
-
Heterogeneity of progesterone receptor content and remodeling by tamoxifen characterize subpopulations of cultured human breast cancer cells: Analysis by quantitative dual parameter flow cytometry
-
Graham ML, Smith JA, Jewett PB, Horwitz KB. Heterogeneity of progesterone receptor content and remodeling by tamoxifen characterize subpopulations of cultured human breast cancer cells: analysis by quantitative dual parameter flow cytometry. Cancer Res 52: 593-602, 1992.
-
(1992)
Cancer Res
, vol.52
, pp. 593-602
-
-
Graham, M.L.1
Smith, J.A.2
Jewett, P.B.3
Horwitz, K.B.4
-
12
-
-
0020358986
-
Evolution of tumor cell heterogeneity during progressive growth of individual lung metastases
-
Poste G, Tzeng J, Doll J, Grieg R, Rieman D, Zeidman I. Evolution of tumor cell heterogeneity during progressive growth of individual lung metastases. Proc Natl Acad Sci (USA) 79: 6574-6578, 1982.
-
(1982)
Proc Natl Acad Sci (USA)
, vol.79
, pp. 6574-6578
-
-
Poste, G.1
Tzeng, J.2
Doll, J.3
Grieg, R.4
Rieman, D.5
Zeidman, I.6
-
13
-
-
0020373697
-
Clonal drift of cell surface, melanogenesis, and experimental metastatic properties of in vivo selected, brain meninges-colonizing murine B16 melanoma
-
Miner KM, Kawaguchi T, Uba GW, Nicolson GL. Clonal drift of cell surface, melanogenesis, and experimental metastatic properties of in vivo selected, brain meninges-colonizing murine B16 melanoma. Cancer Res 42: 4631-4636, 1982.
-
(1982)
Cancer Res
, vol.42
, pp. 4631-4636
-
-
Miner, K.M.1
Kawaguchi, T.2
Uba, G.W.3
Nicolson, G.L.4
-
14
-
-
0023633109
-
Analysis of tumor cell composition of tumors composed of paired mixtures of mammary tumor cell lines
-
Miller BE, Miller FR, Wilburn D, Heppner GH. Analysis of tumor cell composition of tumors composed of paired mixtures of mammary tumor cell lines. Br J Cancer 56:, 561-569, 1987.
-
(1987)
Br J Cancer
, vol.56
, pp. 561-569
-
-
Miller, B.E.1
Miller, F.R.2
Wilburn, D.3
Heppner, G.H.4
-
15
-
-
0024592701
-
Genotypic and phenotypic evidence of clonal interactions in murine tumor cells
-
Itaya T, Judde J, Hunt B, Frost P. Genotypic and phenotypic evidence of clonal interactions in murine tumor cells. J Natl Cancer Inst 81: 664-668, 1989.
-
(1989)
J Natl Cancer Inst
, vol.81
, pp. 664-668
-
-
Itaya, T.1
Judde, J.2
Hunt, B.3
Frost, P.4
-
16
-
-
0018083233
-
Heterogeneity of tumor cells from a single mouse mammary tumor
-
Dexter DL, Kowalski HM, Blazar BA, Fligiel Z, Vogel R, Heppner GH. Heterogeneity of tumor cells from a single mouse mammary tumor. Cancer Res 38: 3174-3181, 1978.
-
(1978)
Cancer Res
, vol.38
, pp. 3174-3181
-
-
Dexter, D.L.1
Kowalski, H.M.2
Blazar, B.A.3
Fligiel, Z.4
Vogel, R.5
Heppner, G.H.6
-
17
-
-
0018075053
-
Heterogeneity in drug sensitivity among tumor cell subpopulations of a single mouse mammary tumor
-
Heppner GH, Dexter DL, DeNucci T, Miller FR, Calabresi P. Heterogeneity in drug sensitivity among tumor cell subpopulations of a single mouse mammary tumor. Cancer Res 38: 3758-3763, 1978.
-
(1978)
Cancer Res
, vol.38
, pp. 3758-3763
-
-
Heppner, G.H.1
Dexter, D.L.2
DeNucci, T.3
Miller, F.R.4
Calabresi, P.5
-
18
-
-
0026040389
-
Tumor subpopulation interactions affecting melphalan sensitivity in palpable mouse mammary tumors
-
Miller BE, Machemer T, Lehotan M, Heppner GH. Tumor subpopulation interactions affecting melphalan sensitivity in palpable mouse mammary tumors. Cancer Res 51: 4378-4387, 1991.
-
(1991)
Cancer Res
, vol.51
, pp. 4378-4387
-
-
Miller, B.E.1
Machemer, T.2
Lehotan, M.3
Heppner, G.H.4
-
19
-
-
0020081481
-
Rapid formation of poly-gamma-glutamyl derivatives of methotrexate and their association with dihydrofolate reductase as assessed by high pressure liquid chromatography in the Ehrlich ascites tumor cell in vitro
-
Fry DW, Yalowich JC, Goldman ID. Rapid formation of poly-gamma-glutamyl derivatives of methotrexate and their association with dihydrofolate reductase as assessed by high pressure liquid chromatography in the Ehrlich ascites tumor cell in vitro. J Biol Chem 257: 1890-1896, 1982.
-
(1982)
J Biol Chem
, vol.257
, pp. 1890-1896
-
-
Fry, D.W.1
Yalowich, J.C.2
Goldman, I.D.3
-
20
-
-
0026075874
-
Identification of a highly glycosylated methotrexate membrane carrier in K562 human erythroleukemia cells up-regulated for tetrahydrofolate cofactor and methotrexate transport
-
Matherly LH, Czajkowski CA, Angeles SM. Identification of a highly glycosylated methotrexate membrane carrier in K562 human erythroleukemia cells up-regulated for tetrahydrofolate cofactor and methotrexate transport. Cancer Res 51: 3420-3426, 1991.
-
(1991)
Cancer Res
, vol.51
, pp. 3420-3426
-
-
Matherly, L.H.1
Czajkowski, C.A.2
Angeles, S.M.3
-
21
-
-
71849104860
-
Protein measurement with the folin phenol reagent
-
Lowry OH, Rosebrough NJ, Farr AL, Randall RJ. Protein measurement with the folin phenol reagent. J Biol Chem 193: 265-275, 1957.
-
(1957)
J Biol Chem
, vol.193
, pp. 265-275
-
-
Lowry, O.H.1
Rosebrough, N.J.2
Farr, A.L.3
Randall, R.J.4
-
22
-
-
30944461310
-
Cellular mechanisms of resistance to methotrexate
-
Sartorelli SC, Lazo JS, Bertino JR (eds), New York: Academic Press
-
Bertino JR, Dolnick BJ, Berenson J, Scheer DI, Kamen BA. Cellular mechanisms of resistance to methotrexate. In: Sartorelli SC, Lazo JS, Bertino JR (eds), Molecular Actions and Targets for Cancer Chemotherapeutic Agents, New York: Academic Press, pp. 385-397, 1981.
-
(1981)
Molecular Actions and Targets for Cancer Chemotherapeutic Agents
, pp. 385-397
-
-
Bertino, J.R.1
Dolnick, B.J.2
Berenson, J.3
Scheer, D.I.4
Kamen, B.A.5
-
23
-
-
0002940875
-
The basis of antifolate cytotoxicity, selectivity, and metabolic transformations: Effects on utilization of endogenous and exogenous folate cofactors
-
Powis G, (ed), Oxford: Pergammon Press
-
Matherly LH, Seither RL, Goldman ID. The basis of antifolate cytotoxicity, selectivity, and metabolic transformations: effects on utilization of endogenous and exogenous folate cofactors. In: Powis G, (ed), Anticancer Drugs: Antimetabolite Metabolism and Natural Anticancer Agents, Oxford: Pergammon Press, pp. 139-177, 1994.
-
(1994)
Anticancer Drugs: Antimetabolite Metabolism and Natural Anticancer Agents
, pp. 139-177
-
-
Matherly, L.H.1
Seither, R.L.2
Goldman, I.D.3
-
24
-
-
0024444318
-
Inherent resistance of human squamous carcinoma cell lines to methotrexate as a result of decreased polyglutamylation of this drug
-
Pizzorno G, Chang YM, McGuire JJ, Bertino JR. Inherent resistance of human squamous carcinoma cell lines to methotrexate as a result of decreased polyglutamylation of this drug. Cancer Res 49: 5275-5280, 1989.
-
(1989)
Cancer Res
, vol.49
, pp. 5275-5280
-
-
Pizzorno, G.1
Chang, Y.M.2
McGuire, J.J.3
Bertino, J.R.4
-
25
-
-
0025817134
-
Decreased folyl-polyglutamate synthetase activity as a mechanism of methotrexate resistance in CCRF-CEM human leukemia sublines
-
McCloskey DE, McGuire JJ, Russell CA, Rowan BG, Bertino JR, Pizzorno G, Mini R. Decreased folyl-polyglutamate synthetase activity as a mechanism of methotrexate resistance in CCRF-CEM human leukemia sublines. J Biol Chem 266: 6181-6187, 1991.
-
(1991)
J Biol Chem
, vol.266
, pp. 6181-6187
-
-
McCloskey, D.E.1
McGuire, J.J.2
Russell, C.A.3
Rowan, B.G.4
Bertino, J.R.5
Pizzorno, G.6
Mini, R.7
-
26
-
-
0017644532
-
Acquired methotrexate resistance in lympnoblasts resulting from altered kinetic properties of dihydrofolate reductase
-
Jackson RC, Niethammer D. Acquired methotrexate resistance in lympnoblasts resulting from altered kinetic properties of dihydrofolate reductase. Eur J Cancer 13: 567-575, 1977.
-
(1977)
Eur J Cancer
, vol.13
, pp. 567-575
-
-
Jackson, R.C.1
Niethammer, D.2
-
27
-
-
0019174166
-
Methotrexate-resistant Chinese hamster ovary cells contain a dihydrofolate reductase with an altered affinity for methotrexate
-
Flintoff WF, Essani K. Methotrexate-resistant Chinese hamster ovary cells contain a dihydrofolate reductase with an altered affinity for methotrexate. Biochemistry 19: 4321-4327, 1980.
-
(1980)
Biochemistry
, vol.19
, pp. 4321-4327
-
-
Flintoff, W.F.1
Essani, K.2
-
28
-
-
0019186331
-
A methotrexate insensitive variant of folate reductase present in two lines of methotrexate-resistant L5178 gamma cells
-
Goldie JH, Krystal G, Hartley D, Gudauskas G, Dedhar S. A methotrexate insensitive variant of folate reductase present in two lines of methotrexate-resistant L5178 gamma cells. Eur J Cancer 16: 1539-1546, 1980.
-
(1980)
Eur J Cancer
, vol.16
, pp. 1539-1546
-
-
Goldie, J.H.1
Krystal, G.2
Hartley, D.3
Gudauskas, G.4
Dedhar, S.5
-
29
-
-
0019817704
-
Properties of an altered dihydrofolate reductase encoded by amplified genes in cultured mouse fibroblasts
-
Haber DA, Beverly SM, Kiely ML, Schimke RT. Properties of an altered dihydrofolate reductase encoded by amplified genes in cultured mouse fibroblasts. J Biol Chem 256: 9501-9510, 1981.
-
(1981)
J Biol Chem
, vol.256
, pp. 9501-9510
-
-
Haber, D.A.1
Beverly, S.M.2
Kiely, M.L.3
Schimke, R.T.4
|