Nicked free β-subunit of human chorionic gonadotropin: A potential new marker for Down syndrome screening

American Journal of Obstetrics and Gynecology

Volumn 174, Issue 2, 1996, Pages 609-611

  Rotmensch, S ^a   Liberati, M ^a   Kardana, A ^a   Copel, J A ^a   Ben Rafael, Z ^a   Cole, L A ^a  

^a HASHARON HOSPITAL   (Israel)

Author keywords

Down syndrome; Human chorionic gonadotropin; serum screening

Indexed keywords

CHORIONIC GONADOTROPIN BETA SUBUNIT;

AMNIOCENTESIS; ARTICLE; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOWN SYNDROME; GENETIC SCREENING; GESTATIONAL AGE; HUMAN; MATERNAL BLOOD; PREGNANCY COMPLICATION; PRENATAL DIAGNOSIS; PRIORITY JOURNAL;

EID: 0029671445     PISSN: 00029378     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0002-9378(96)70435-0     Document Type: Article

References (8)

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4. LA Cole A Kardana SY Park GD Braunstein The deactivation of hCG by nicking and dissociation J Clin Endocrinol Metab 76 1993 704 710
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6. LA Cole A Kardana P Andrade-Gordon The heterogeneity of human chorionic gonadotropin (hCG), III: the occurrence and biological and immunological activities of nicked hCG Endocrinology 129 1991 1559 1567
7. A Kardana LA Cole Human chorionic gonadotropin β-subunit nicking enzymes in pregnancy and cancer patient serum J Clin Endocrinol Metab 79 1994 761 767
8. GE Palomaki GJ Knight J McCarthy JE Haddow JH Eckfeldt Maternal serum screening for fetal Down syndrome in the United States: a 1992 survey AM J OBSTET GYNECOL 169 1993 1558 1562