5-hydroxytryptamine depolarizes neurons of cat pancreatic ganglia

Journal of the Autonomic Nervous System

Volumn 57, Issue 1-2, 1996, Pages 78-86

  Ma, R C ^a,b   Szurszewski, J H ^a  

^a MAYO CLINIC   (United States)

^b ANHUI MEDICAL UNIVERSITY   (China)

Author keywords

5 hydroxytryptamine; Cat; Membrane depolarization; Pancreas; Pancreatic ganglion

Indexed keywords

ATROPINE; CALCIUM; CHLORIDE; POTASSIUM; SEROTONIN; BEMESETRON; HEXAMETHONIUM; MIANSERIN; RENZAPRIDE; SEROTONIN 1 RECEPTOR; SEROTONIN 2 RECEPTOR; SEROTONIN 3 RECEPTOR; SPIPERONE; ZIMELDINE;

ANIMAL; ARTICLE; CAT; DRUG EFFECT; EVOKED RESPONSE; GANGLION; PANCREAS; ADOLESCENT; ANIMAL EXPERIMENT; CONTROLLED STUDY; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; ATROPINE; CALCIUM; CATS; CHLORIDES; EVOKED POTENTIALS; GANGLIA; PANCREAS; POTASSIUM; SEROTONIN;

EID: 0029671404     PISSN: 01651838     EISSN: None     Source Type: Journal    
DOI: 10.1016/0165-1838(95)00100-X     Document Type: Article

References (33)

1. Akasu, T. and Nishimura, T., Presynaptic modulation by 5-hydroxytryptamine of the nicotinic transmission in rabbit parasympathetic ganglia, J. Auton. Nerv. Syst., 33 (1991) 163-164.
2. Askenase, P.W., Bursztajn, S., Gershon, M.D. and Gershon, R.K., T cell dependent mast cell degranulation and release of serotonin in murine delayed-type hypersensitivity, J. Exp. Med., 152 (1980) 1358-1374.
3. Cajal, S. and Ramon, Y., New Ideas on the Structure of the Nervous System in Man and Vertebrates (Translated from the French by N. Swanson and L.W. Swanson). MIT Press, Cambridge, MA, 1990,
4. Drapanas, T. and Pollack, E.I., The effect of serotonin and serotonin precursor on pancreatic secretion in the dog, Surgery St. Louis, 48 (1960) 854-861.
5. 1A receptor, Nature, 335 (1988) 358-360.
6. Feldman Jr., J.M., Quickel, K.E. and Lebovitz, H.E., Potentiation of insulin secretion in vitro by serotonin antagonists, Diabetes, 21 (1972) 779-788.
7. 4 receptors, Gastroenterology, 100 (1991) A443 (Abstract).
8. Fuller, R.W., Drugs affecting serotonin neurons, Prog. Drug Res., 35 (1990) 85-108.
9. 2 receptors localized to subsets of guinea pig myenteric neurons, J. Auton. Nerv. Syst., 32 (1991) 1-12.
10. Hoyer, D., Clarke, D.E., Fozard, J.D., Hartig, P.R., Martin, G.R., Mylecharane, E.J., Saxena, P.R. and Humphrey, P.P.A., International Union of Pharmacology Classification of Receptors for 5-hydroxytryptamine (Serotonin), Pharmacol. Rev., 46 (1994) 157-203.
11. King, B.F., Love, J.A. and Szurszewski, J.H., Intracellular recordings from pancreatic ganglia of the cat, J. Physiol., 419 (1989) 379-403.
12. Kirchgessner, A.L., Aldersberg, M.A. and Gershon, M., Colonization of the developing pancreas by neural precursors from the bowel, Dev. Dyn., 194 (1992) 142-154.
13. Kirchgessner, A.L. and Gershon, M.D., Innervation of the pancreas by neurons in the gut, J. Neurosci., 10 (1990) 1626-1642.
14. Kirchgessner, A.L. and Gershon, M.D., Innervation and regulation of the pancreas by neurons in the gut, Ergeb. Gastroenterol., 26 (1991) 230-233.
15. 1P receptors, J. Comp. Neurol., 327 (1993) 233-250.
16. 1P receptors in the guinea pig pancreas. Am. J. Physiol., 262 (1992) G553-G566.
17. Kirchgessner, A.L. and Pintar, J.E., Guinea pig pancreatic ganglia: projections, transmitter content, and the type-specific localization of monoamine oxidase, J. Comp. Neurol, 305 (1991) 613-631.
18. Langerhans, P., Contributions to the Microscopic Anatomy of the Pancreas (M.D. Thesis), Berlin: 1869 (Translated by H. Morrison). The Johns Hopkins Hospital Press, Baltimore, MD, 1937,
19. Larsson, L.-I., Innervation of the pancreas by substance P, vasoactive intestinal polypeptide and gastrin/CCK immunoreactive nerves, J. Histochem. Cytochem., 27 (1979) 1283-1284.
20. Ma, R. and Szurszewski, J.H., 5-Hydroxytryptamine (5-HT) evokes fast and slow depolarization in cat intrapancreatic neurons, Gastroenterology, 102 (1992) A744 (Abstract).
21. Mawe, G.M., Theresa, A., Branchek, A. and Gershon, M.D., Blockade of 5-HT-mediated enteric slow EPSPs by BRL 24924: gastrokinetic effects, Am. J. Physiol., 257 (1989) G386-G396.
22. Mori, J., Satoh, H. and Honda, F., Amines and the rat exocrine pancreas: (3) effects of amines on pancreatic secretion, Jpn. J. Pharmacol., 29 (1979) 923-933.
23. Neild, T.O., Slowly-developing depolarization of neurones in the guinea-pig inferior mesenteric ganglion following repetitive stimulation of the preganglionic nerves, Brain Res., 140 (1978) 231-239.
24. Pontroli, A.E., Micossi, P. and Foa, P.P., Effects of serotonin, of its biosynthetic precursors and of the anti-serotonin agent metergoline on the release of glucagon and insulin from the rat pancreas, Horm. Metab. Res., 10 (1978) 177-262.
25. 3 receptors, Trends Neurosci., 9 (1986) 424-428.
26. Sanger, G.J., Increased gut cholinergic activity and antagonism of 5-hydroxytryptamine M-receptors by BRL 24924: potential clinical importance of BRL 24924, Br. J. Pharmacol., 91 (1987) 77-87.
27. Surprenant, A. and Crist, J., Electrophysiological characterization of functionally distinct 5-hydroxytryptamine receptors on guinea pig submucous plexus, Neuroscience, 24 (1988) 283-295.
28. Takaki, M., Branchek, T., Tamir, H. and Gershon, M.D., Specific antagonism of enteric neural serotonin receptors by dipeptides of 5-hydroxytroptophan: evidence that serotonin is a mediator of slow synaptic excitation in the myenteric plexus, J. Neurosci., 5 (1985) 1769-1780.
29. Talib, M., Raptis, S., Schroder, K.E. and Pfeiffer, E.F., Serotonin and insulin release in vitro, Diabetologia, 4 (1968) 253-256.
30. Wade, P.R., Mawe, G.M., Branchek, T.A. and Gershon, M.D., Use of stereoisomers of zacopride to analyze actions of 5-hydroxytryptamine on enteric neurons, Am. J. Physiol., 260 (1991) G80-G90.
31. Wade, P.R., Tamir, H., Kirchgessner, A.L. and Gershon, M.D., Analysis of the role of 5-HT in the enteric nervous system using anti-idiotopic antibodies to 5-HT receptors, Am. J. Physiol., 29 (1994) G403-G416.
32. Wallis, D.I. and Dun, N.J., Fast and slow depolarizing responses of guinea-pig coeliac ganglion cells to 5-hydroxytryptamine, J. Auton. Nerv. Syst., 21 (1987) 185-194.
33. Wallis, D.I. and Dun, N.J., A comparison of fast and slow depolarization evoked by 5-HT in guinea-pig coeliac ganglion cells in vitro, Br. J. Pharmacol., 93 (1988) 110-120.