Conformation of the T-Cell antigen Receptor-β chain C-domain contributes to vβ3 epitope recognition by monoclonal antibody KJ25

Scandinavian Journal of Immunology

Volumn 43, Issue 2, 1996, Pages 140-145

  Li, Zhan Guo ^a   Kemp, O ^a   Longhurst, T ^b   Manolios, N ^a  

^a UNIVERSITY OF SYDNEY   (Australia)

^b UNIVERSITY OF TECHNOLOGY SYDNEY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

EPITOPE; INTERLEUKIN 2 RECEPTOR; LYMPHOCYTE ANTIGEN RECEPTOR; MONOCLONAL ANTIBODY; T LYMPHOCYTE RECEPTOR;

ARTICLE; HUMAN; HUMAN CELL; IMMUNOGLOBULIN GENE; PRIORITY JOURNAL; T LYMPHOCYTE;

EID: 0029671339     PISSN: 03009475     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-3083.1996.d01-21.x     Document Type: Article

References (19)

1. Wileman T, Kane LP, Young J, Carson GR, Terhorst C. Associations between subunit ectodomains promote T cell antigen receptor assembly and protect against degradation in the ER. J Cell Biol 1993;122:67-78.
2. Manolios N, Kemp O, Li ZG. The T cell antigen receptor α and β chains interact via distinct regions with CD3 chains. Eur J Immunol 1994;24:84-92.
3. Hurtley S, Helenius A. Protein oligomerization in the endoplasmic reticulum. Annu Rev Cell Biol 1989;5:277-307.
4. Pullen AM, Marrack P, Kappler JW. The T-cell repertoire is heavily influenced by tolerance to polymorphic self-antigens. Nature 1988;335:796-801.
5. Kubo R.T., Born W., Kappler J.W., Marrack P. & Pigeon M. Characterisation of a monoclonal antibody which detects all murine αb T cell receptors. J Immunol 1989;142:2736-42.
6. Gascoigne NRJ. Transport and secretion of truncated T cell receptor β-chain occurs in the absence of association with CD3. J Biol Chem 1990;266:9296-301.
7. Ceredig R, Lowenthal JW, Nabholz M, Macdonald HR. Expression of interleukin-2 receptors as a differentiation marker on intrathymic stem cells. Nature 1985;314:98-100.
8. Higuchi R, Krummel B, Saiki R. A general method of in vitro preparation and specific mutagenesis of DNA fragments: study of protein and DNA interactions. Nucleic Acids Res 1988;16:7351-67.
9. Seed B. An LFA-3 cDNA encodes a phospholipid-linked membrane protein homologous to its receptor. Nature 1987; 329:840-2.
10. Takebe Y, Seiki M, Fujisawa JI et al. SR alpha promoter: an efficient and versatile mammalian cDNA expression system composed of the Simian virus 40 early promoter and the R-U5 segment of human T-cell leukemia virus type I long terminal repeat. Mol Cell Biol 1988;8:466-72.
11. Sanger F, Nicklen S, Coulson AR. DNA sequencing with chain-terminating inhibitors. Proc Natl Acad Sci USA 1977;74:5463-7.
12. Manolios N, Bonifacino JS, Klausner RD. Transmembrane helical interactions and the assembly of the T cell receptor complex. Science 1990;249:274-7.
13. Manolios N, Letourner F, Bonifacino JS, Klausner RD. Pair-wise, cooperative and inhibitory interactions describe the assembly and probable structure of the T-cell antigen receptor. EMBO J 1990;10:1643-51.
14. Sambrook J, Fritsch EF, Maniatis T. Extraction, purification and analysis of messenger RNA from eukaryotic cells. In: Molecular Cloning, A Laboratory Manual. 2nd edn. New York: Cold Spring Harbor Laboratory Press, 1989.
15. O'Farrell PZ, Goodman HM, O'Farrell PH. High resolution two-dimensional electrophoresis of basic as well as acidic proteins. Cell 1977;12:1133-1142.
16. Caspar-Bauguil S, Arnaud J, Gouaillard C, Hou X, Geisler C, Rubin B. Functionally important amino acids in the TCR revealed by immunoselection of membrane TCR-negative T cells. J Immunol 1994;152:5288-98.
17. Casorati G, Traunecker A, Karjalainen K. The T cell receptor αβ V-J shuffling shows lack of autonomy between the combining site and the constant domain of the receptor chains. Eur J Immunol 1993;23:586-9.
18. Simon T, Rajewsky K. Antibody domain mutants demonstrate autonomy of the antigen binding site. EMBO J 1990;9:1051-6.
19. Bentley GA, Boulot G, Karjalainen K, Mariuzza RA. Crystal structure of the β chain of a T cell antigen receptor. Science 1995;267:1984-7.