Effects of N1-guanyl-1,7-diaminoheptane, an inhibitor of deoxyhypusine synthase, on the growth of tumorigenic cell lines in culture

Biochimica et Biophysica Acta - Molecular Cell Research

Volumn 1310, Issue 1, 1996, Pages 119-126

  Shi, Xiao Ping ^a   Yin, Kuo Chang ^a   Ahern, Janet ^a   Davis, Lenora J ^a   Stern, Andrew M ^a   Waxman, Lloyd ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

Antiproliferation; Cell growth; Deoxyhypusine synthase; Eukaryotic translation initiation factor 5A; Tumorigenic cell line

Indexed keywords

1 GUANYLAMINO 7 HEPTANAMINE; AMINOGUANIDINE; ANTINEOPLASTIC AGENT; CYCLOHEXIMIDE; DEOXYHYPUSINE SYNTHASE INHIBITOR; EFLORNITHINE; ENZYME INHIBITOR; INITIATION FACTOR; MIMOSINE; PUROMYCIN; UNCLASSIFIED DRUG; DEOXYHYPUSINE SYNTHASE; DRUG DERIVATIVE; EIF-5A; GUANIDINE DERIVATIVE; GUANINE; INITIATION FACTOR 5A; N(1) GUANYL 1,7 DIAMINOHEPTANE; N(1)-GUANYL-1,7-DIAMINOHEPTANE; OXIDOREDUCTASE; RNA BINDING PROTEIN;

ANIMAL CELL; ARTICLE; CELL CULTURE; CELL CYCLE; CELL GROWTH; CELL STRAIN 3T3; CELL TRANSFORMATION; CHO CELL; CONTROLLED STUDY; CULTURE MEDIUM; DRUG SENSITIVITY; HELA CELL; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; ANIMAL; CELL DIVISION; CELL LINE; COMPARATIVE STUDY; DRUG ANTAGONISM; DRUG EFFECT; METABOLISM;

ANIMALIA; EUKARYOTA;

3T3 CELLS; ANIMALS; CELL CYCLE; CELL DIVISION; CELL LINE, TRANSFORMED; ENZYME INHIBITORS; GUANIDINES; GUANINE; HELA CELLS; HUMANS; MICE; OXIDOREDUCTASES ACTING ON CH-NH GROUP DONORS; PEPTIDE INITIATION FACTORS; RNA-BINDING PROTEINS; TUMOR CELLS, CULTURED;

EID: 0029671261     PISSN: 01674889     EISSN: None     Source Type: Journal    
DOI: 10.1016/0167-4889(95)00165-4     Document Type: Article

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