[3H]sumatriptan binding sites in human brain: Regional-dependent labelling of 5-HT1D and 5-HT1F receptors

European Journal of Pharmacology

Volumn 295, Issue 2-3, 1996, Pages 271-274

  Pascual, Julio ^a   Del Arco, Carmen ^a   Romón, Tamara ^a   Del Olmo, Elena ^a   Pazos, Angel ^a,b  

^a HOSPITAL UNIVERSITARIO MARQUÉS DE VALDECILLA   (Spain)

^b UNIVERSITY OF CANTABRIA   (Spain)

Author keywords

5 Carboxamidotryptamine; 5 HT1D; 5 HT1F; Metergoline; Migraine; Receptor; 3H Sumatriptan

Indexed keywords

5 CARBAMOYLTRYPTAMINE; METERGOLINE; RADIOLIGAND; SEROTONIN; SEROTONIN 1 RECEPTOR; SEROTONIN 1D RECEPTOR; SEROTONIN 1F RECEPTOR; SUMATRIPTAN;

ADULT; ARTICLE; AUTOPSY; AUTORADIOGRAPHY; BINDING COMPETITION; BINDING SITE; BRAIN CORTEX; BRAIN REGION; CONTROLLED STUDY; CORPUS STRIATUM; FRONTAL CORTEX; GLOBUS PALLIDUS; HIPPOCAMPUS; HUMAN; HUMAN TISSUE; MEMBRANE BINDING; PRIORITY JOURNAL; SUBSTANTIA NIGRA; TISSUE DISTRIBUTION;

EID: 0029671212     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/0014-2999(95)00748-2     Document Type: Article

References (18)

1. 1 receptor subtype coupled to the inhibition of adenylate cyclase, Proc. Natl. Acad. Sci. USA 90, 408.
2. Boess, F.G. and I.L. Martin, 1994, Molecular biology of 5-HT receptors, Neuropharmacology 33, 275.
3. 1D binding sites in human and guinea-pig brain using different radioligands, Mol. Brain Res. 21, 19.
4. 1F receptor messenger RNA in rodent and primate brain, Neuropharmacology 33, 367.
5. Dβ) encoded by an intronless gene on chromosome 6, Proc. Natl. Acad. Sci. USA 89, 5522.
6. 1D-type serotonin receptor. Mol. Pharmacol. 40, 143.
7. 1Dβ receptor subtype in human and bovine cerebral arteries, Mol. Pharmacol. 44, 242.
8. 1E) in human brain: interaction with a GTP-binding protein, J. Neurochem. 53, 465.
9. Martin, G.R. and P.P.A. Humphrey, 1994, Classification review. Receptors for 5-hydroxytryptamine: current perspectives on classification and nomenclature, Neuropharmacology 33, 261.
10. Parsons, A.A., 1991, 5-HT receptors in human and animal cerebrovasculature, Trends Pharmacol. Sci. 12, 310.
11. Pazos, A., D. Hoyer and J.M. Palacios, 1984, The binding of serotonergic ligands to the porcine choroid plexus: characterization of a new type of serotonin recognition site, Eur. J. Pharmacol. 106, 539.
12. Pazos, A., A. Probst and J.M. Palacios, 1987, Serotonin receptors in the human brain. III. Autoradiographic mapping of serotonin-1 receptors, Neuroscience 21, 97.
13. Peroutka, S.J., 1990, Developments in 5-hydroxytryptamine receptor pharmacology in migraine, Neurologic Clinics: Headache 8, 829.
14. 1F receptor binding sites in the guinea-pig brain, Br. J. Pharmacol. Proceedings Suppl. 114, 364P.
15. 3H-ultrofilm: application to multiple benzodiazepine receptors, Proc. Natl. Acad. Sci. USA 87, 59.
16. 1D receptors: a progress review, Neurochem. Res. 15, 567.
17. 1β, Proc. Natl. Acad. Sci. USA 89, 3630.
18. Zifa, E. and G. Fillion, 1992, 5-Hydroxytryptamine receptors, Pharmacol. Rev., 44, 401.