Heat-shock protein and c-fos expression in focal microvascular brain damage

Journal of Cerebral Blood Flow and Metabolism

Volumn 16, Issue 1, 1996, Pages 82-91

  Lindsberg, Perttu J ^a,b   Frerichs, Kai U ^c   Sirén, Anna Leena ^a   Hallenbeck, John M ^c   Nowak, Thaddeus S ^d  

^a UNIVERSITY OF HELSINKI   (Finland)

^b Uniformed Services University of the Health Sciences   (United States)

^c NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE   (United States)

^d UNIVERSITY OF TENNESSEE HEALTH SCIENCE CENTER   (United States)

Author keywords

Brain edema; C fos; Focal brain injury; Heat shock proteins; Hsp72

Indexed keywords

GLIAL FIBRILLARY ACIDIC PROTEIN; HEAT SHOCK PROTEIN; PROTEIN C FOS; TRANSCRIPTION FACTOR;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BLOOD BRAIN BARRIER; BRAIN CORTEX; BRAIN INJURY; GENE EXPRESSION REGULATION; IMMUNOCYTOCHEMISTRY; MALE; MICROVASCULATURE; NEODYMIUM LASER; NONHUMAN; ONCOGENE C FOS; PRIORITY JOURNAL; RAT;

EID: 0029671115     PISSN: 0271678X     EISSN: None     Source Type: Journal    
DOI: 10.1097/00004647-199601000-00010     Document Type: Article

References (43)

1. An G, Lin T-N, Liu J-S, Xue J-J, He Y-Y, Hsu CY (1993) Expression of c-fos and and c-jun family genes after focal cerebral ischemia. Ann Neurol 33:457-464
2. Blake MJ, Nowak TS Jr, Holbrook NJ (1990) In vivo hyperthermia induces expression of HSP70 mRNA in brain regions controlling the neuroendocrine response to stress. Mol Brain Res 8:89-92
3. Brown IR, Rush S, Ivy GO. (1989) Induction of a heat-shock gene at the site of tissue injury in the rat brain. Neuron 2:1559-1564
4. Dragunow M, Robertson HA (1988) Brain injury induces c-fos protein(s) in nerve and glial-like cells in adult mammalian brain. Brain Res 455:295-299
5. Feinberg AP, Vogelstein B (1983) A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity. Analyt Biochem 132:6-13
6. Frerichs KU, Lindsberg PJ, Hallenbeck JM, Feuerstein G (1990) Platelet-activating factor and progressive brain damage following focal brain injury. J Neurosurg 73:223-233
7. Gass P, Spranger M, Herdegren T, Bravo R, Köck P, Hacke W, Kiessling M (1992) Induction of FOS and JUN proteins fol- lowing focal ischemia in the rat cortex: differential effect of MK-801. Acta Neuropathol 84:545-553
8. Gonzalez MF, Shiraishi K, Hisanaga K, Sagar SM, Mandabach M, Sharp FR (1989) Heat shock proteins as markers of neural injury. Mol Brain Res 6:93-100
9. Herrera DG, Robertson HA (1989) Unilateral induction of c-fos protein in cortex following cortical devascularization. Brain Res 503:205-213
10. Herrera DG, Robertson HA (1990) Application of potassium chloride to the brain surface induces the c-fos protooncogene:reversal by MK-801. Brain Res 510:166-170
11. Jacewicz M, Kiessling M, Pulsinelli WA (1986) Selective gene expression in focal cerebral ischemia. J Cereb Blood Flow Metab 6:263-272
12. Jacewicz M, Tanabe J, Pulsinelli WA (1992) The CBF threshold and dynamics for focal cerebral infarction in spontaneously hypertensive rats. J Cereb Blood Flow Metab 12:359-370
13. Jørgensen MB, Deckert J, Wright DC, Gehlert DR (1989) Delayed c-fos proto-oncogene expression in the rat hippocampus induced by transient global cerebral ischemia: an in situ hybridization study. Brain Res 484:393-398
14. Kawagoe J, Abe K, Sato S, Nagano I, Nakamura S, Kogure K (1992) Distribution of heat shock protein (HSP) 70 and heat shock cognate protein (HSC) 70 mRNAs after transient focal ischemia in rat brain. Brain Res 587:195-202
15. Kiessling M, Herchenhan E, Eggert HR (1990) Cerebrovascular and metabolic effects on the rat brain of focal Nd:YAG laser irradiation. J Neurosurg 73:909-917
16. Kiessling M, Stumm G, Xie Y, et al. (1993) Differential transcription and translation of immediate early genes in the gerbil hippocampus after transient global ischemia. J Cereb Blood Flow Metab 13:914-924
17. Kinouchi H, Sharp FR, Hill MP, Koistinaho J, Sagar SM, Chan PH (1993) Induction of 70 kDa heat shock protein and hsp70 mRNA following transient focal cerebral ischemia in the rat. J Cereb Blood Flow Metab 13:105-115
18. Klatzo I (1985) Brain oedema following brain ischemia and the influence of therapy. Br J Anaesthesiol 57:18-22
19. Li Y, Chopp M, Garcia JH, Yoshida Y, Zhang ZG, Levine SR. (1992) Distribution of the 72-kd heat-shock protein as a function of transient focal cerebral ischemia in rats. Stroke 23: 1293-1298
20. Lindsberg PJ, Frerichs KU, Burris JA, Hallenbeck JM, Feuerstein G (1991a) Cortical microcirculation in a new model of focal laser-induced secondary brain damage. J Cereb Blood Flow Metab 11:88-98
21. Lindsberg PL, Siren A-L, Hallenbeck JM (1991) Microvascular perfusion during focal vasogenic brain edema: a scanning laser fluorescence microscopy study [Abstract]. Soc Neurosci 16:55
22. Marini AM, Kozuka M, Lipsky RL, Nowak TS Jr (1990) 70-kilodalton heat shock protein induction in cerebellar astrocytes and cerebellar granule cells in vitro: comparison with immunocytochemical localization after hyperthermia in vivo. J Neurochem 54:1509-1516
23. Miller AD, Curran T, Verma IM (1984) c-Fos protein can induce cellular transformation: a novel mechanism of activation of a cellular oncogene. Cell 36:51-60
24. Miller EK, Raese JD, Morrison-Bogorad M (1991) Expression of heat shock protein 70 and heat shock cognate 70 messenger RNAs in rat cortex and cerebellum after heat shock or amphetamine treatment. J Neurochem 56:2060-2071
25. Nowak TS Jr (1991) Localization of 70 kDa stress protein mRNA induction in gerbil brain after ischemia. J Cereb Blood Flow Metab 11:432-439
26. Nowak TS Jr, Bond U, Schlesinger MJ (1990a) Heat shock RNA levels in brain and other tissues after hyperthermia and transient ischemia. J Neurochem 54:451-458
27. Nowak TS Jr, Ikeda J, Nakajima T (1990) 70-kDa heat shock protein and c-fos gene expression after transient ischemia. Stroke 21 (suppl III): 107-111
28. Pardue S, Groshan K, Raese JD, Morrison-Bogorad M (1992) Hsp70 mRNA induction is reduced in neurons of aged rat hippocampus after thermal stress. Neurobiol Aging 13:661-672
29. Roychoudhury R, Wu R (1980) Terminal transferase-catalyzed addition of nucleotides to the 3′ termini of DNA. Methods Enzymol 65:43-62
30. Schindler M, Trosko JE, Wade MH (1987) Fluorescence photobleaching assay of tumor promoter 12-O-tetradecanoylphorbol 13-acetate inhibition of cell-cell communication. Methods Enzymol 141:439-447
31. Schindler M, Jiang L-W, Swaisgood M, Wade MH (1989) Analysis, selection, and sorting of anchorage dependent cells under growth conditions. In: Methods in Cell Biology, Vol 32, Vesicular Transport, Part 8 (Tartakoff AM ed), New York, Academic Press, pp 1-11
32. Sharp FR, Lowenstein D, Simon R, Hisanaga K (1991) Heat shock protein hsp72 induction in cortical and striatal astrocytes and neurons following infarction. J Cereb Blood Flow Metab 11:621-627
33. Simon RP, Cho H, Gwinn R, Lowenstein DH (1991) The temporal profile of 72-kDa heat-shock protein expression following global ischemia. J Neurosci 11:881-889
34. Sloviter RS, Lowenstein DH (1992) Heat shock protein expression in vulnerable cells of the rat hippocampus as an indicator of excitation induced neuronal stress. J Neurosci 12: 3004-3009
35. Sprang GK, Brown IR (1987) Selective induction of a heat shock gene in fibre tracts and cerebellar neurons of the rabbit brain detected by in situ hybridization. Mol Brain Res 3:89-93
36. Takeda Y, Jacewicz M, Takeda Y, Nowak TS Jr, Pulsinelli WA (1993) DC-potential and energy metabolites in the focal ischemia. J Cereb Blood Flow Metab 13 (suppl, 1):S450
37. Tanno H, Nockels RP, Pitts LH, Noble LJ (1993) Immunolocalization of heat shock protein after fluid percussive brain injury and relationship to breakdown of the blood-brain barrier. J Cereb Blood Flow Metab 13:116-124
38. Uemura Y, Kowall NW, Moskowitz MA (1991) Focal ischemia in rats causes time-dependent expression of c-fos protein immunoreactivity in widespread regions of ipsilateral cortex. Brain Res 552:99-105
39. Vass K, Welch WJ, Nowak TS Jr (1988) Localization of 70 kD stress protein induction in gerbil brain after ischemia. Acta Neuropathol 77:128-135
40. Vass K, Berger ML, Nowak TS Jr, Welch WJ, Lassmann H (1989) Induction of stress protein HSP70 in nerve cells after status epilepticus in the rat. Neurosci Lett 100:259-264
41. Welsh FA, Moyer DJ, Harris VA. (1992) Regional expression of heat shock protein-70 mRNA and c-fos mRNA following focal ischemia in rat brain. J Cereb Blood Flow Metab 12: 204-212
42. Wessel TC, Joh TH, Volpe BT. (1991) In situ hybridization analysis of c-fos and c-jun expression in the rat brain following transient forebrain ischemia. Brain Res 567:231-240
43. Williams JL, Shea M, Jones SC (1993) Evidence that heterogeneity of cerebral blood flow does not involve vascular recruitment. Am J Physiol 264 (Heart Circ Physiol 33): H1740-H1743