Protective immunity to shiga-like toxin I following oral immunization with shiga-like toxin I B-subunit-producing Vibrio cholerae CVD 103-HgR

Infection and Immunity

Volumn 64, Issue 1, 1996, Pages 355-357

  Acheson, David W K ^a   Levine, Myron M ^b   Kaper, James B ^b   Keusch, Gerald T ^a  

^a TUFTS MEDICAL CENTER   (United States)

^b UNIVERSITY OF MARYLAND   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHOLERA TOXIN B SUBUNIT; CHOLERA VACCINE; NEUTRALIZING ANTIBODY; VEROTOXIN;

ANIMAL EXPERIMENT; ANTIBODY RESPONSE; ARTICLE; CONTROLLED STUDY; HELA CELL; HUMAN; HUMAN CELL; IMMUNITY; IMMUNIZATION; INOCULATION; INTESTINE MUCOSA; INTRAPERITONEAL DRUG ADMINISTRATION; INTRAVENOUS DRUG ADMINISTRATION; MALE; NONHUMAN; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; RABBIT; TOXIN STRUCTURE; VIBRIO CHOLERAE;

EID: 0029671025     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/iai.64.1.355-357.1996     Document Type: Article

References (23)

1. Acheson, D. W. K., S. B. Caldcrwood, S. A. Boyko, L. L. Lmcicomc, A. V. Kane, A. Donohue-Rolfe, and G. T. Keusch. 1993 Comparison ot Shiga-like toxin I B-subunit expression and localization in Escheticlua coli and Vibrio cholerae by using tro or iron-regulated promoter systems. Infect Immun. 61:1098-1104
2. Acheson, D. W. K., S. DeBreucker, A. Donohue-Rolfe, K. Kozak, A. Yi. and G. T. Keusch. 1994. Development of a clinically useful diagnostic enzyme immunoassay for enterohemorrhagic Eschertchia coli infection, p. 109-112. In M. A. Karmali and A. G. Goglio (ed.), Recent advances in Verocytotoxm producing Escherichm coli infections. Elsevier Science, Amsterdam
3. Acheson, D. W. K., S. A. De Breucker, M. Jacewicz, L. L. Lincicnme, A. Donohue-Ralfe, A. V. Kane, and G. T. Keusch. 1995. Expression and pun-flcation of Shiga-hke toxin II B subunils. Infeet Immun 63:301-308.
4. Acheson, D. W. K., A. V. Kane, and G. T. Keusch. 1995 Unpublished data
5. Endo, Y., K. Tsurugi, T. Yutsudo, Y. Takeda, T. Ogasawara. and K. Igarashi. 1988. Site of action of a Vero toxin (VT2) from Eschtnchia cull O157 H7 and of Shiga toxin on cucaryotic nbosomes. Eur. J. Biochem. 171:45-50.
6. Gentry, M. K., and J. M. Dalrymple. 1980 Quantitative microtiter cylotoxicity assay for Shigella toxin J Clin Mierobiol. 12:361-366.
7. Gordon, V. M., S. C. Whipp, H. W. Moon, A. D. O'Brien, and J. E. Samuel. 1992. An enzymatic mutant of Shiga-like toxin II variant is a vaccine candidate for edema disease of swine Infect. Immun. 60:485-490.
8. Hofmann, S. L. 1993. Southwestern Internal Medicine Conference Shigalike toxms in hemolytic-uremic syndrome and thrombotic thrombocytopenic purpura Am. J. Med. Sci. 306:398-406
9. Jacewicz, M., H. Clausen, E. Nudeiman, A. Donohue-Rolfe, and G. T. Keusch. 1986 Pathogenesis of Shugelli diarrhea XI Isolation of a Shigella toxin-binding glycolipid from rabbit jejunum and HeLa ceils and its identification as globotnaosyl ceramide. J. Exp. Med. 163:1391-1404
10. Jackson, M. P., R. J. Neill, A. D. O'Brien, R. K. Holmes, and J. W. Newland. 1987 Nuclcotide sequence analysis and comparison ot the structural genes for Shiga-likc toxin I and Shiga-like toxin II encoded by bactenophages from Escherichia coli 933. FEMS Microbiol. Lett. 44:109-114.
11. Kandel, G., A. Donohue-Rolfe, M. Donowitz, and G. T. Keusch. 1989. Pathogenesis of Shigella diarrhea. XVI. Selective targeting of Shiga toxin to villus cells of rabbit jejunum explains the effect of the toxin on intestinal electrolyte transport J. Clin. Invest. 84:1509-1517
12. Karmali, M. A. 1989. Infection by verocytotoxm-producmg Eschenclua coli. Clin Microbiol. Rev. 2:15-38
13. Karmali, M. A., M. Petric, C. Lim, P. C. Fleming, G. S. Arbus, and H. Lior. 1985 The association between idiopathic hemolytic uremic syndrome and infection by Vcrotoxin-producing Eschericita coli. J. Infect. Dis. 151:775-782
14. Keusch, G. T., G. F. Grady, L. J. Mata, and J. Melver. 1972. The pathogenesis of Shigella diarrhea. I. Enterotoxin production by Shigella dvsenteria I. J. Clin. Invest. 51:1212-1218
15. Levine, M. M., D. Herrington, G. Losonsky, B. G. Tall, J. B. Kaper, J. Ketley, C. O. Tacket, and S. Cryz. 1988. Safety, immunogematy, and efficacy of recombinant live otal cholera vaccines, CVD 103 and CVD 103-HgR. Lancet ii:467-470
16. Morrison, D. M., D. L. J. Tyrrell, and L. D. Jewell. 1986 Colonie biopsy in verotoxin-mduccd hemorrhagic colitis and thrombotic thrombocytopenic purpura (TTP). Am J Clin Pathol 86:108-112.
17. Mullelt, C., D. W. K. Acheson, L.-Y. Tseng, and E. Buedeker. 1994. High titer serum antibody against the B subunit of Shiga-like toxin I protects in a model of enterohemorrhagic Escherichia coli (EHEC) colitis Gastroenlerology 106:A740.
18. Obrig, T. G., P. J. Del Vecchio, J. E. Brown. T. P. Moran, B. M. Rowland, T. K. Judge, and S. W. Rothman. 1988 Direct cytotoxic action of Shiga toxin on human vascular endothelial cells. Infect Immun. 56:2373-2378.
19. Stein, P. E., A. Boodhoo, G. J. Tyrrell, J. L. Brunton, and R. J. Read. 1992. Crystal structure of the cell binding B oligomer of Verotoxim-1 from E coli. Nature (London) 355:748-750.
20. Steinberg, S. E., J. G. Banwell, J. H. Yardley, G. T. Keusch, and T. R. Hendrrs. 1975. Comparison of secretory and histological effects of Shigella and Cholera enteroloxins in rabbit jejunum. Gastroenterology 68:309-317.
21. van de Kar, N. C. A. J., L. A. H. Monnens. M. A. Karmali, and V. W. M. van Hinsbergh. 1992 Tumor necrosis factor and inierleukm-1 induce expression ot the Verocytotoxin receptor globotnaosylceramide on human cndothelial cells implication for the pathogenesis ot the hemolytic uremic syndrome. Blood 80:2755-2764.
22. Waddell, T., S. Head, M. Petric, A. Cohen, and C. Lingwood. 1988 Globotriaosyl ceramide is specifically recognized by the Eschcrichia coli verotoxin. Biochem. Biophys Res Commun. 152:674-679
23. Wadolkowski, E. A., L. M. Sung. J. A. Burris, J. E. Samuel, and A. D. O'Brien. 1990. Acute renal tubular necrosis and death of mice orally infected with Exchericlua coli strains that produce Shiga-hkc toxin type II. Infect Immun. 58:3959-3965