ω-conotoxin GVIA-resistant neurotransmitter release in postganglionic sympathetic nerve terminals

Neuroscience

Volumn 70, Issue 3, 1996, Pages 817-824

  Smith, A B ^a   Cunnane, T C ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

ATP secretion; calcium channel blocker; co transmission; frequency dependent facilitation; guinea pig vas deferens; grammotoxin SIA

Indexed keywords

ADENOSINE TRIPHOSPHATE; ADENOSINE TRIPHOSPHATE DERIVATIVE; ALPHA 2 ADRENERGIC RECEPTOR; CALCIUM CHANNEL; CALCIUM CHANNEL BLOCKING AGENT; NIFEDIPINE; NORADRENALIN; OMEGA AGATOXIN; OMEGA CONOTOXIN; OMEGA GRAMMOTOXIN; PRAZOSIN; PURINE P2 RECEPTOR; TETRODOTOXIN; UNCLASSIFIED DRUG; YOHIMBINE;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; GUINEA PIG; INTRACELLULAR RECORDING; MALE; NEUROTRANSMITTER RELEASE; NONHUMAN; PRIORITY JOURNAL; SYMPATHETIC NERVE; VAS DEFERENS;

EID: 0029670988     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0306-4522(96)83018-1     Document Type: Article

References (24)

1. Åstrand P. and Stjärne L. (1989) On the secretory activity of single varicosities in the sympathetic nerves innervating the rat tail artery. J. Physiol. 409, 207-220.
2. Blakeley A. G. H., Brown D. A., Cunnane T. C., French A. M., McGrath J. C. and Scott N. C. (1981) Effects of nifedipine on electrical and mechanical responses of the rat and guinea-pig vas deferens. Nature 294, 759-760.
3. Blakeley A. G. H. and Cunnane T. C. (1979) The packeted release of transmitter from the sympathetic nerves of the guinea-pig vas deferens: an electrophysiological study. J. Physiol. 296, 85-96.
4. Brock J. A. and Cunnane T. C. (1987) Relationship between the nerve action potential and transmitter release from sympathetic postganglionic nerve terminals. Nature 326, 605-607.
5. Brock J. A. and Cunnane T. C. (1988) Electrical activity at the sympathetic neuroeffector junctions in the guinea-pig vas deferens. J. Physiol. 399, 607-632.
6. Brock J. A. and Cunnane T. C. (1992) Electrophysiology of neuroeffector transmission in smooth muscle. In Autonomic Neuroeffector Mechanisms (eds Burnstock G. and Hoyle C. H. V.), pp. 121-213. Harwood Academic, Reading, U.K.
7. + channel blockers on nerve impulses recorded from postganglionic sympathetic nerve terminals. J. Physiol. (in press).
8. Brock J. A. and Cunnane T. C. (1992) Electrophysiology of neuroeffector transmission in smooth muscle. In Autonomic Neuroeffector Mechanisms (eds Burnstock G. and Hoyle C. H. V.), pp. 121-213. Harwood Academic, Reading, U.K.
9. 2-Adrenoceptor-mediated autoinhibition of sympathetic transmitter release in guinea-pig vas deferens studied by intracellular and focal extracellular recording of junction potentials and currents. Naunyn-Schmiedeberg's Arch. Pharmac. 342, 45-52.
10. Brock J. A., Cunnane T. C., Evans R. J. and Ziogas J. (1989) Inhibition of transmitter release from sympathetic nerve endings by ω-conotoxin. Clin. exp. Pharmac. Physiol. 16, 333-339.
11. Burnstock G. (1990) Cotransmission. The Fifth Heymans Lecture, Ghent, 17 February 1990. Archs int. Pharmacodyn. Thér. 304, 7-33.
12. Cunnane T. C. and Searl T. (1994) Neurotransmitter release mechanisms in autonomic nerve terminals. In Molecular and Cellular Mechanisms of Neurotransmitter Release (eds Stjärne L., Greengard, Grillner, Hökfelt and Ottoson), pp. 425-459.
13. Cunnane T. C. and Stjärne L. (1984) Transmitter secretion from individual varicosities of guinea-pig and mouse vas deferens: all-or-none and extremely intermittent. Neuroscience 13, 1-20.
14. 2+ channels in mammalian central neurons. Trends Neurosci. 18, 89-98.
15. Hoyle C. H. V. (1992) Transmission: purines. In Autonomic Neuroeffector Mechanisms (eds Burnstock G. and Hoyle C. H. V.), pp. 367-407. Harwood Academic, Reading, U.K.
16. Keith R. A., Defeo P. A., Lampe R. A., Spence K. T., Lo M. M. S. and Ffrench-Mullen J. M. H. (1992) Inhibition of neuronal calcium channels by a fraction from Grammastola spatulata venom. Pharmac. Commun. 1, 19-25.
17. Lampe R. A., Defeo P. A., Davison M. D., Young J., Herman J. L., Spreen R. C., Horn M. B., Mangano T. D. and Keith R. A. (1993) Isolation and pharmacological characterisation of ω-grammotoxin SIA, a novel peptide inhibitor of neuronal voltage-sensitive calcium channel responses. Molec. Pharmac. 44, 451-460.
18. Lavidis N. and Bennett M. (1992) Probabilistic secretion of quanta from visualised varicosities sympathetic nerve varicosities in the mouse vas deferens. J. Physiol. 454, 9-26,
19. 2+ current in rat dorsal-root ganglion neurons. Pflügers Arch. 426, 214-220.
20. Smith A. B. and Cunnane T. C. (1994) ω-Conotoxin GVIA-resistant excitatory junction potentials in the guinea-pig vas deferens. Br. J. Pharmac. 113, 19P.
21. Sneddon P. and Burnstock G. (1984) Inhibition of excitatory junction potentials in guinea-pig vas deferens by β-methylene-ATP: further evidence for ATP and noradrenaline as co-transmitters. Eur. J. Pharmac. 106, 149-152.
22. Turner T. J., Lampe R. A. and Dunlap K. (1995) Characterisation of presynaptic calcium channels with ω-conotoxin MVIIC and ω-grammotoxin SIA: role for a resistant calcium channel type in neurosecretion. Molec. Pharmac. 47, 348-353,
23. Wardell C. F. and Cunnane T. C. (1994) Biochemical machinery involved in the release of ATP from sympathetic nerve terminals. Br. J. Pharmac. 111, 975-977.
24. Wheeler D. B., Sather W. A., Randall A. D. and Tsien R. W. (1994) Distinctive properties of a neuronal calcium channel and its contribution to excitatory synaptic transmission in the central nervous system. In Molecular and Cellular Mechanisms of Neurotransmitter Release (eds Stjärne L., Greengard, Grillner, Hökfelt and Ottoson), pp. 155-171.