EJ-Ras Inhibits Phospholipase Cγ1 but Not Actin Polymerization Induced by Platelet-Derived Growth Factor-BB via Phosphatidylinositol 3-Kinase

Circulation Research

Volumn 78, Issue 2, 1996, Pages 312-321

  Heldman, Alan W ^a   Kandzari, David E ^a   Tucker, Robert W ^a   Crawford, Lawrence E ^a   Fearon, Eric R ^b   Koblan, Kenneth S ^c   Goldschmidt Clermont, Pascal J ^a,d  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c MERCK RESEARCH LABORATORIES   (United States)

^d JOHNS HOPKINS UNIVERSITY   (United States)

Author keywords

Actin; EJ Ras; p21ras; Platelet derived growth factor receptor; Tyrosine kinase

Indexed keywords

ACTIN; GUANINE NUCLEOTIDE BINDING PROTEIN; INOSITOL TRISPHOSPHATE; PHOSPHATIDYLINOSITOL 4,5 BISPHOSPHATE; PHOSPHATIDYLINOSITOL KINASE; PHOSPHOLIPASE C; PHOSPHOLIPASE C GAMMA1; PLATELET DERIVED GROWTH FACTOR BB; PROTEIN P21; RECOMBINANT PHOSPHOLIPASE C; UNCLASSIFIED DRUG; WORTMANNIN;

ACTIN POLYMERIZATION; ANIMAL CELL; ARTICLE; ATHEROGENESIS; CELL MIGRATION; CELL TRANSFORMATION; CONTROLLED STUDY; ENZYME INHIBITION; FIBROBLAST; MOLECULAR MODEL; MOUSE; NONHUMAN; ONCOGENE RAS; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; REGULATORY MECHANISM; RESTENOSIS; SMOOTH MUSCLE FIBER;

1-PHOSPHATIDYLINOSITOL 3-KINASE; 3T3 CELLS; ACTINS; ANIMALS; CELL ADHESION; CELL LINE, TRANSFORMED; CELL SIZE; GENE TRANSFER TECHNIQUES; ISOENZYMES; MICE; PHOSPHOLIPASE C; PHOSPHOLIPASE C GAMMA; PHOSPHOTRANSFERASES (ALCOHOL GROUP ACCEPTOR); PLATELET-DERIVED GROWTH FACTOR; PROTO-ONCOGENE PROTEINS P21(RAS);

EID: 0029670961     PISSN: 00097330     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.RES.78.2.312     Document Type: Article

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