Angiotensin II decreases a resting K+ conductance in rat bulbospinal neurons of the C1 area

Circulation Research

Volumn 78, Issue 2, 1996, Pages 274-282

  Li, Yu Wen ^a   Guyenet, Patrice G ^a,b  

^a UNIVERSITY OF VIRGINIA   (United States)

^b UNIVERSITY OF VIRGINIA HEALTH SYSTEM   (United States)

Author keywords

angiotensin II; C1 neurons; resting K+ conductance; rostral ventrolateral medulla; sympathetic vasomotor tone

Indexed keywords

ALPHA ADRENERGIC RECEPTOR STIMULATING AGENT; ANGIOTENSIN; ANGIOTENSIN 2 RECEPTOR; BRIMONIDINE; LOSARTAN; METHYLTRANSFERASE; PHENYLETHANOLAMINE; POTASSIUM ION; TETRODOTOXIN; TYROSINE 3 MONOOXYGENASE;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CARDIOVASCULAR REFLEX; CONTROLLED STUDY; MEDULLA OBLONGATA; NERVE CELL; NEWBORN; NONHUMAN; POTASSIUM CONDUCTANCE; PRIORITY JOURNAL; RAT; RECEPTOR UPREGULATION; SLOW INWARD CURRENT; SYMPATHETIC INNERVATION; VOLTAGE CLAMP;

EID: 0029670960     PISSN: 00097330     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.RES.78.2.274     Document Type: Article

References (46)

1. Dampney RAL. Functional organization of central pathways regulating the cardiovascular system. Physiol Rev. 1994;74:323-364.
2. Guyenet PG. Role of the ventral medulla oblongata in blood pressure regulation. In: Loewy AD, Spyer KM, eds. Central Regulation of Autonomic Functions. New York, NY: Oxford University Press; 1990:145-167.
3. Sasaki S, Dampney RA. Tonic cardiovascular effects of angiotensin II in the ventrolateral medulla. Hypertension. 1990;15:274-283.
4. Li YW, Polson JW, Dampney RAL. Angiotensin-II excites vasomotor neurons but not respiratory neurons in the rostral and caudal ventrolateral medulla. Brain Res. 1992;577:161-164.
5. Sasaki S, Li YW, Dampney RAL. Comparison of the pressor effects of angiotensin-II and angiotensin-III in the rostral ventrolateral medulla. Brain Res. 1993;600:335-338.
6. Allen AM, Dampney RA, Mendelsohn FA. Angiotensin receptor binding and pressor effects in cat subretrofacial nucleus. Am J Physiol. 1988;255:H1011-H1017.
7. Saigusa T, Head GA. Renal sympathetic baroreflex effects of angiotensin II infusions into the rostral ventrolateral medulla of the rabbit. Clin Exp Pharmacol Physiol. 1993;20:351-354.
8. Hirooka Y, Dampney RAL. Endogenous angiotensin within the rostral ventrolateral medulla facilitates the somatosympathetic reflex. J Hypertens. 1995;13:747-754.
9. Muratani H, Ferrario CM, Averill DB. Ventrolateral medulla in spontaneously hypertensive rats: role of angiotensin-II. Am J Physiol. 1993;264:R388-R395.
10. Li YW, Guyenet PG. Neuronal excitation by angiotensin II in the rostral ventrolateral medulla of the rat in vitro. Am J Physiol. 1995; 268:R272-R277.
11. Lind RW, Swanson LW, Ganten D. Organization of angiotensin II immunoreactive cells and fibers in the rat central nervous system. Neuroendocrinology. 1985;40:2-24.
12. Aldred GP, Chai SY, Song K, Zhuo J, MacGregor DP, Mendelsohn FA. Distribution of angiotensin II receptor subtypes in the rabbit brain. Regul Pept. 1993;44:119-130.
13. Song K, Allen AM, Paxinos G, Mendelsohn FAO. Angiotensin II receptor subtypes in rat brain. Clin Exp Pharmacol Physiol. 1991;18: 93-96.
14. Song K, Allen AM, Paxinos G, Mendelsohn FAO. Mapping of angiotensin II receptor subtype heterogeneity in rat brain. J Comp Neurol. 1992;316:467-484.
15. Allen AM, Chai SY, Clevers J, McKinley MJ, Paxinos G, Mendelsohn AO. Localization and characterization of angiotensin II receptor binding and angiotensin converting enzyme in the human medulla oblongata. J Comp Neurol. 1988;269:249-264.
16. Kangrga IM, Loewy AD. Whole-cell recordings from visualized C1 adrenergic bulbospinal neurons: ionic mechanisms underlying vasomotor tone. Brain Res. 1995;670:215-232.
17. Li YW, Bayliss DA, Guyenet PG. C1 neurons of neonatal rats: intrinsic beating properties and alpha-2 adrenergic receptors. Am J Physiol. In press.
18. Edwards FA, Konnerth A, Sakmann B, Takahashi TA. Thin slice preparation for patch clamp recordings from neurones of the mammalian central nervous system. Trends Pharmacol Sci. 1989;62:67.
19. Aghajanian GK, Rasmussen K. Intracellular studies in the facial nucleus illustrating a simple new method for obtaining viable motoneurons in adult rat brain slices. Synapse. 1989;3:331-338.
20. Alreja M, Aghajanian GK. Pacemaker activity of locus-coerulcus neurons: whole-cell recordings in brain slices show dependence on cAMP and protein kinase-A. Brain Res. 1991;556:339-343.
21. Tucker DC, Saper CB, Ruggiero DA, Reis DJ. Organization of central adrenergic pathways, I: relationships of ventrolateral medullary projections to the hypothalamus and spinal cord. J Comp Neurol. 1987;259:591-603.
22. Milner TA, Pickel VM, Park DH, Joh TH, Reis DJ. Phenylethanolamine N-methyltransferase-containing neurons in the rostral ventrolateral medulla of the rat, I: normal ultrastructure. Brain Res. 1987;411:28-45.
23. Guyenet PG, Stornetta RL, Riley T, Norton FR, Rosin DL, Lynch KR. Alpha(2A)-adrenergic receptors are present in lower brainstem catecholaminergic and serotonergic neurons innervating spinal cord. Brain Res. 1994;638:285-294.
24. Paxinos G, Watson C. The Rat Brain in Stereotaxic Coordinates. 2nd ed. Sydney, Australia: Academic Press; 1986.
25. Yang CR, Phillips MI, Renaud LP. Angiotensin II receptor activation depolarizes rat supraoptic neurons in vitro. Am J Physiol. 1992;263:R1333-R1338.
26. Barnes KL, McQueeney AJ, Ferrario CM. Receptor subtype that mediates the neuronal effects of angiotensin II in the rat dorsal medulla. Brain Res Bull. 1993;31:195-200.
27. Sun MK, Guyenet PG. Effects of vasopressin and other neuropeptides on rostral medullary sympathoexcitatory neurons 'in vitro.' Brain Res. 1989;492:261-270.
28. Bayliss DA, Viana F, Berger AJ. Mechanisms underlying excitatory effects of thyrotropin-releasing hormone on rat hypoglossal motoneurons 'in vitro.' J Neurophysiol. 1992;68:1733-1745.
29. Hoyer J, Popp R, Meyer J, Galla HJ, Gogelein H. Angiotensin II, vasopressin and GTP [gamma-S] inhibit inward-rectifying K channels in porcine cerebral capillary endothelial cells. J Membr Biol. 1991;123:55-62.
30. Bkaily G, Peyrow M, Sculptoreanu A, Jacques D, Chahine M, Regoli D, Sperelakis N. Angiotensin II increases Isi and blocks IK in single aortic cell of rabbit. Pflugers Arch. 1988;412:448-450.
31. Shapiro MS, Wollmuth LP, Hille B. Angiotensin II inhibits calcium and M current channels in rat sympathetic neurons via G proteins. Neuron. 1994;12:1319-1329.
32. Nicoll RA, Malenka RC, Kauer JA. Functional comparison of neurotransmitter receptor subtypes in mammalian central nervous system. Physiol Rev. 1990;70:513-565.
33. Livingston CA, Berger AJ. Response of neurons in the dorsal motor nucleus of the vagus to thyrotropin-releasing hormone. Brain Res. 1993;621:97-105.
34. Fisher ND, Nistri A. Substance P and TRH share a common effector pathway in rat spinal motoneurones: an in vitro electrophysiological investigation. Neurosci Lett. 1993;153:115-119.
35. Guerineau NC, Gahwiler BH, Gerber U. Reduction in resting K conductance by metabotropic glutamate and muscarinic receptors in rat CA3 cells: mediation by G-proteins. J Physiol (Lond). 1994; 474:27-33.
36. Madison DV, Lancaster B, Nicoll RA. Voltage clamp analysis of cholinergic action in the hippocampus. J Neurosci. 1987;7:733-741.
37. McCormick DA, Williamson A. Modulation of neuronal firing mode in cat and guinea pig LGNd by histamine: possible cellular mechanisms of histaminergic control of arousal. J Neurosci. 1991; 11:3188-3199.
38. McCormick DA. Cellular mechanisms underlying cholinergic and noradrenergic modulation of neuronal firing mode in the cat and guinea pig dorsal lateral geniculate nucleus. J Neurosci. 1992;12: 278-289.
39. McCormick DA, Wang Z. Serotonin and noradrenaline excite GABAergic neurones of the guinea-pig and cat nucleus reticularis thalami. J Physiol (Lond). 1991;442:235-255.
40. Palant CE, Ross MJ. Role of ionic currents in the physiological response to angiotensin II. Renal Physiol Biochem. 1991;14:186-198.
41. Bacal K, Kunze DL. Dual effects of angiotensin II on calcium currents in neonatal rat nodose neurons. J Neurosci. 1994;14: 7159-7167.
42. Bescond J, Bois P, Petit-Jacques J, Lenfant J. Characterization of an angiotensin II-activated chloride current in rabbit sino-atrial cells. J Membr Biol. 1994;140:153-161.
43. Chan RKW, Chan YS, Wong TM. Effects of [Sar1, Ile8]-angiotensin II on rostral ventrolateral medulla neurons and blood pressure in spontaneously hypertensive rats. Neuroscience. 1994;63:267-277.
44. Haselton JR, Guyenet PG. Electrophysiological characterization of putative C1 adrenergic neurons in the rat. Neuroscience. 1989;30: 199-214.
45. Dampney RAL. The subretrofacial vasomotor nucleus: anatomical, chemical and pharmacological properties and role in cardiovascular regulation. Prog Neurobiol. 1994;42:197-228.
46. Morrison SF, Milner TA, Reis DJ. Reticulospinal vasomotor neurons of the rat rostral ventrolateral medulla: relationship to sympathetic nerve activity and the C1 adrenergic cell group. J Neurosci. 1988;8:1286-1301.