The mutation gly142 → glu in human lipoprotein lipase produces a missorted protein that is diverted to lysosomes

Journal of Biological Chemistry

Volumn 271, Issue 4, 1996, Pages 2139-2146

  Buscà, Roser ^a   Martínezi, Mònica ^a   Vilella, Elisabet ^b   Pognonec, Philippe ^c   Deeb, Samir ^d   Auwerx, Johan ^e   Reina, Manuel ^a   Vilaró, Senén ^a  

^a UNIVERSITY OF BARCELONA   (Spain)

^b Hospital St Joan   (Spain)

^c CENTRE DE BIOCHIMIE   (France)

^d UNIVERSITY OF WASHINGTON   (United States)

^e INSTITUT PASTEUR DE LILLE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

LEUPEPTIN; HEPARIN; LIPOPROTEIN LIPASE; PRIMER DNA; PROTEINASE INHIBITOR;

AMINO ACID SUBSTITUTION; ARTICLE; ENZYME ACTIVITY; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; HUMAN CELL; IMMUNOBLOTTING; IMMUNOELECTRON MICROSCOPY; LYSOSOME; PRIORITY JOURNAL; PROTEIN ANALYSIS; QUALITY CONTROL; RADIOIMMUNOASSAY; SITE DIRECTED MUTAGENESIS; ANIMAL; CELL COMPARTMENTALIZATION; CELL CULTURE; CERCOPITHECUS; CHEMISTRY; ENZYMOLOGY; FLUORESCENCE MICROSCOPY; FLUORESCENT ANTIBODY TECHNIQUE; GENETIC TRANSFECTION; IMMUNOHISTOCHEMISTRY; METABOLISM; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; STRUCTURE ACTIVITY RELATION;

ANIMALS; BASE SEQUENCE; CELL COMPARTMENTATION; CELLS, CULTURED; CERCOPITHECUS AETHIOPS; DNA PRIMERS; FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT; HEPARIN; HUMANS; IMMUNOHISTOCHEMISTRY; LEUPEPTINS; LIPOPROTEIN LIPASE; LYSOSOMES; MICROSCOPY, FLUORESCENCE; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; PROTEASE INHIBITORS; STRUCTURE-ACTIVITY RELATIONSHIP; TRANSFECTION;

ANIMALIA; CERCOPITHECUS;

EID: 0029670911     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.271.4.2139     Document Type: Article

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