Detection of IL-1α, IL-1β and IL-1 receptor antagonist in blister fluid of bullous pemphigoid

Journal of Dermatological Science

Volumn 11, Issue 2, 1996, Pages 142-147

  Schmidt, Enno ^a   Mittnacht, Alexander ^a   Schömig, Heike ^a   Dummer, Reinhard ^b   Bröcker, Eva Bettina ^a   Zillikens, Detlef ^a,c  

^a UNIVERSITY OF WÜRZBURG   (Germany)

^b UNIVERSITY OF ZURICH   (Switzerland)

^c MEDICAL COLLEGE OF WISCONSIN   (United States)

Author keywords

Cytokine; Keratinocyte; Suction blister

Indexed keywords

INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; INTERLEUKIN 1ALPHA; INTERLEUKIN 1BETA;

ARTICLE; BLISTER; CLINICAL ARTICLE; CONTROLLED STUDY; HUMAN; KERATINOCYTE; PEMPHIGOID; PRIORITY JOURNAL;

EID: 0029670741     PISSN: 09231811     EISSN: None     Source Type: Journal    
DOI: 10.1016/0923-1811(95)00435-1     Document Type: Article

References (29)

1. Ishiko A, Shimizu H, Kikuchi A, Ebihara T, Hashimoto T Nishikawa T: Human autoantibodies against the 230 kDa bullous pemphigoid antigen (BPAG1) bind only to the intracellular domain of the hemidesmosome, whereas those against the 180 kDa bullous pemphigoid antigen (BPAG2) bind along the plasma membrane of the hemidesmosome in normal human and swine skin. J Clin Invest 91: 1608-1615, 1993.
2. Giudice GJ, Emery DJ, Zelickson BD, Anhalt GJ, Liu Z Diaz LA: Bullous pemphigoid and herpes gestationis autoantibodies recognize a common non-collagenous site on the BP180 ectodomain. J Immunol 151: 5742-5750, 1993.
3. Gammon WR, Merritt CC, Lewis DM, Sam WM Jr, Wheeler CE Jr, Carlo JR: Functional evidence for complement-activating immune complexes in the skin of patients with bullous pemphigoid. J Invest Dermatol 78: 52-57, 1982.
4. Wintroub BU, Mihm MC, Goetzl EJ, Soter NA, Austen KF: Morphologic and functional evidence for release of mast-cell products in bullous pemphigoid. N Engl J Med 298: 417-421 1978.
5. Dvorak AM, Mihm MC Jr, Osage FE, Kwan TH, Austen KF Wintroub BU: Bullous pemphigoid, an ultrastructural study of the inflammatory response: eosinophil, basophil and mast cell granule changes in multiple biopsies from one patient. J Invest Dermatol 78: 91-101, 1982.
6. Emtestam L, Hovmark A, Lindberg M, Åsbrink E: Human epidermal Langerhans cells in bullous pemphigoid. Acta Derm Venereol (Stockh) 67: 529-532, 1987.
7. Karashima T, Hachisuka H, Okubo K, Sasai Y: Epidermal keratinocytes of bullous pemphigoid express intercellular adhesion molecule-1 (ICAM-1). J Dermatol 19: 82-86, 1992.
8. Zillikens D, Schuessler M, Dummer R, Porzsolt F Hartmann AA, Burg G: Tumor necrosis factor in blister fluids of bullous pemphioid. Eur J Dermatol 2: 429-431, 1992.
9. Zentner A, Rendl J, Grelle I, Dummer R, Bröcker EB Zillikens D: Elevated levels of soluble tumor necrosis factor receptor I in blister fluids of bullous pemphigoid and suction blisters. Arch Dermatol Res 286: 355-357, 1994.
10. Endo H, Iwamoto I, Fujita M, Okamoto S, Yoshida S: Increased immunoreactive interleukin-5 levels in blister fluids of bullous pemphigoid. Arch Dermatol Res 284: 312-314, 1992.
11. Tamaki K, So K, Furuya T, Furue M: Cytokine profile of patients with bullous pemphigoid. Br J Dermatol 130: 128-129 1994.
12. Kaneko F, Minagawa T, Takiguchi Y, Suzuki M, Itoh N: Role of cell-mediated immune reaction in blister formation of bullous pemphigoid. Dermatology 184: 34-39, 1992.
13. Zillikens D, Ambach A, Schuessler M, Dummer R Hartmann AA, Burg G: The interleukin-2 receptor in lesions and serum of bullous pemphigoid. Arch Dermatol Res 284: 141-145 1992.
14. Kutsch CL, Norris DA, Arend WP: Tumor necrosis factor-a induces interleukin-1α and interleukin-1 receptor antagonist production by cultured human keratinocytes. J Invest Dermatol 101: 79-85, 1993.
15. Dinarello CA: Interleukin-1 and interleukin-1 antagonism. Blood 77: 1627-1652, 1991.
16. Kiistala U: Suction blister device for separation of viable epidermis from dermis. J Invest Dermatol 50: 129-137 1968.
17. Kylmaniemi M, Autio P, Oikarinen A: Interleukin 1α (IL-1α) in human skin in vivo: lack of correlation to markers of collagen metabolism. Acta Derm Venereol (Stockh) 74: 364-367, 1994.
18. Nozaki S, Feliciani C, Sauder DN: Keratinocyte cytokines. Adv Dermatol 7: 83-101, 1991.
19. Kupper TS: The activated keratinocyte: a model for inducible cytokine production by non-bone marrow-derived cells in cutaneous inflammatory and immune responses. J Invest Dermatol 94: 146S-150S, 1990.
20. Kresicki RF, Hatfield CA, Bienkowski MJ, et al: Regulation of expression of IL-1 receptor antagonist protein in human synovial and demal fibroblasts. J Immunol 150: 4008-4018 1993.
21. Mizutani H, Black R, Kupper TS: Human keratinocytes produce but do not process pro-interleukin-1β (IL-1β): different strategies of IL-1 production and processing in monocytes and keratinocytes. J Clin Invest 87: 1066-1071, 1991.
22. Enk AH, Angeloni VL, Udey MC, Katz SI: An essential role for Langerhans cell-derived IL-1β in the initiation of primary immune response in skin. J Immunol 150: 3698-3704 1993.
23. Ambach A, Zillikens D, Klingert B, Hartmann AA, Burg G: Immunophenotyping of the mononuclear infiltrate in bullous pemphigoid. Hautarzt 43: 81-85, 1992.
24. Nestor MS, Cochran AJ, Ahmed AR: Mononuclear cell infiltrates in bullous pemphigoid. J Invest Dermatol 88: 172-175, 1987.
25. Dinarello CA: The biology of interleukin-1, In Interleukins: Molecular Biology and Immunology. Edited by T Kishimoto. Karger, Basel, 1992, pp. 1-32.
26. Boxman I, Löwik C, Aarden L, Ponec M: Modulation of IL-6 production and IL-1 activity by keratinocyte-fibroblast interaction. J Invest Dermatol 101: 316-324, 1993.
27. Bochner BS, Luscinskas FW, Gimbrone MA Jr, et al: Adhesion of human basophils, eosinophils and neutrophils to interleukin-1-activated human vascular endothelial cells: contribution of endothelial cell adhesion molecules. J Exp Med 173: 1553-1557, 1991.
28. Grando SA, Glukhenky BT, Drannik GN, Epshtein EV Kostromin AP, Korostash TA: Mediators of inflammation in blister fluids from patients with pemphigus vulgaris and bullous pemphigoid. Arch Dermatol 125: 925-930, 1989.
29. Haskill S, Martin G, Van Le L, et al: cDNA cloning of an intracellular form of the human interleukin-1 receptor antagonist associated with epithelium. Proc Natl Acad Sci USA 88: 3681-3685, 1991.