Site-directed mutagenesis of Cys324 and Cys331 in human cytosolic phospholipase A2: Locus of action of thiol modification reagents leading to inactivation of cPLA2

Biochemistry

Volumn 35, Issue 10, 1996, Pages 3156-3161

  Li, Bin ^a,b   Xia, Ling ^a,c   Krantz, Allen ^a,d   Yuan, Zhengyu ^a,e  

^a Synrex Incorporated   (Canada)

^b ROCHE BIOSCIENCE   (United States)

^c HOSPITAL FOR SICK CHILDREN   (Canada)

^d Red Cell Inc   (United States)

^e AFFYMAX RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PHOSPHOLIPASE A2;

AMINO ACID SUBSTITUTION; ARTICLE; CYTOSOL; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME MODIFICATION; HUMAN; PRIORITY JOURNAL; SITE DIRECTED MUTAGENESIS;

AMINO ACID SEQUENCE; ANIMALS; CELLS, CULTURED; CYSTEINE; CYTOSOL; HUMANS; IODOACETAMIDE; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; PHOSPHOLIPASES A; STRUCTURE-ACTIVITY RELATIONSHIP; SULFHYDRYL REAGENTS; TRANSFECTION;

EID: 0029670498     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi952141x     Document Type: Article

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