G protein-coupled receptors and receptor kinases: From molecular biology to potential therapeutic applications: Understanding the intimate connection between activation and desensitization in seven-membrane-spanning receptors may lead to new therapies for heart disease

Nature Biotechnology

Volumn 14, Issue 3, 1996, Pages 283-286

  Lefkowitz, Robert J ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GUANINE NUCLEOTIDE BINDING PROTEIN; MEMBRANE RECEPTOR; PHOSPHOTRANSFERASE; G PROTEIN COUPLED RECEPTOR; RECEPTOR;

DESENSITIZATION; HUMAN; LIGAND BINDING; MOLECULAR BIOLOGY; PHOSPHORYLATION; PRIORITY JOURNAL; PROTEIN DOMAIN; SHORT SURVEY; SIGNAL TRANSDUCTION;

ANIMALS; BIOTECHNOLOGY; BLOOD PROTEINS; GTP-BINDING PROTEINS; HEART DISEASES; HUMANS; MODELS, BIOLOGICAL; MYOCARDIAL CONTRACTION; ONCOGENE PROTEINS; PHOSPHOPROTEINS; RECEPTOR PROTEIN-TYROSINE KINASES; RECEPTORS, CELL SURFACE; SIGNAL TRANSDUCTION;

EID: 0029670261     PISSN: 10870156     EISSN: 15461696     Source Type: Journal    
DOI: 10.1038/nbt0396-283     Document Type: Article

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