Distinct effects of Nω-nitro-L-arginine on seizures induced by several drugs in mice

Pharmacology Biochemistry and Behavior

Volumn 53, Issue 3, 1996, Pages 673-677

  Hara, Shuichi ^a   Kuriiwa, Fumi ^a   Iwata, Nobuhisa ^a   Mukai, Toshiji ^a   Kano, Sadao ^a   Endo, Takahiko ^a  

^a TOKYO MEDICAL UNIVERSITY   (Japan)

Author keywords

Bicuculline; Mouse; N Methyl DL aspartate; Nitric oxide; N nitro L arginine; Pentylenetetrazol; Picrotoxin

Indexed keywords

BICUCULLINE; N METHYLASPARTIC ACID; N(G) NITROARGININE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE INHIBITOR; PENTETRAZOLE; PICROTOXIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CLONIC SEIZURE; CONTROLLED STUDY; DEATH; DRUG ANTAGONISM; INTRAPERITONEAL DRUG ADMINISTRATION; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; SUBCUTANEOUS DRUG ADMINISTRATION; TONIC SEIZURE;

ANIMALS; ARGININE; BICUCULLINE; DOSE-RESPONSE RELATIONSHIP, DRUG; MALE; MICE; MICE, INBRED ICR; PENTYLENETETRAZOLE; PICROTOXIN; SEIZURES; TIME FACTORS;

ANIMALIA;

EID: 0029670242     PISSN: 00913057     EISSN: None     Source Type: Journal    
DOI: 10.1016/0091-3057(95)02068-3     Document Type: Article

References (30)

1. Bagetta, G.; Iannone, M.; Scorsa, A. M.; Nisticò, G. Tacrine-induced seizures and brain damage in LiCl-treated rats can be prevented by Nω-nitro-L-arginine methyl ester. Eur. J. Pharmacol. 213:301-304; 1992.
2. Bredt, D. S.; Snyder, S. H. Nitric oxide, a novel neuronal messenger. Neuron 8:3-11; 1992.
3. Buisson, A.; Lakhmeche, N.; Verrecchia, C.; Plotkine, M.; Boulu, R. G. Nitric oxide: An endogenous anticonvulsant substance. Neuroreport 4:444-446; 1993.
4. De Sarro, G. B.; Di Paola, E. D.; De Sarro, A.; Vidal, M. J. Role of nitric oxide in the genesis of excitatory amino acid-induced seizures from the deep prepiriform cortex. Fundam. Clin. Pharmacol. 5:503-511; 1991.
5. De Sarro, G.; Di Paola, E. D.; De Sarro, A.; Vidal, M. J. L-Arginine potentiates excitatory amino acid-induced seizures elicited in the deep prepiriform cortex. Eur. J. Pharmacol. 230:151-158; 1993.
6. Dingledine, R.; McBain, C. J.; McNamara, J. O. Excitatory amino acid receptors in epilepsy. Trends Pharmacol. Sci. 11:334-338; 1990.
7. G-nitroarginine in brain in vitro and in vivo. Biochem Biophys. Res. Commun. 176:1136-1141; 1991.
8. Faraci, F. M.; Breese, K. R.; Heistad, D. D. Nitric oxide contributes to dilation of cerebral arterioles during seizures. Am. J. Physiol. 265:H2209-H2212; 1993.
9. Gale, K. Progression and generalization of seizure discharge: Anatomical and neurochemical substrates. Epilepsia 29(Suppl. 2): S15-S34; 1988.
10. Hara, S.; Satoh, T.; Kitagawa, H. Dose-dependence of the effect of hydratazine on the central nervous system in rats. J. Pharm. Pharmacol. 35:50-52; 1983
11. Klatt, P.; Schmidt, K.; Brunner, F.; Mayer, B. Inhibitors of brain nitric oxide synthase: Binding kinetics, metabolism, and enzyme inactivation. J. Biol. Chem. 269:1674-1680; 1994.
12. Lei, S. Z.; Pan, Z.-H.; Aggarwal, S. K.; Chen, H.-S. V.; Hartman, J.; Sucher, N. J.; Lipton, S. A. Effect of nitric oxide production on the redox modulatory site of the NMDA receptor-channel complex. Neuron 8:1087-1099; 1992.
13. Lipton, S. A.; Choi, Y.-B.; Pan, Z.-H.; Lei, S. Z.; Chen, H.-S. V.; Sucher, N. J.; Loscalzo, J.; Singel, D. J.; Stamler, J. S. A redox-based mechanism for the neuroprotective and neurodestructive effects of nitric oxide and related nitroso-compounds. Nature 364:626-632; 1993.
14. Luo, D.; Leung, E.; Vincent, S. R. Nitric oxide-dependent efflux of cGMP in rat cerebellar cortex: An in vivo microdialysis study. J. Neurosci. 14:263-271; 1994.
15. A receptor channels. Annu. Rev. Neurosci. 17:569-602; 1994.
16. Maione, S.; Berrino, L.; Vitagliano, S.; Leyva, J.; Rossi, F. Pregnenolone sulfate increases the convulsant potency of N-methyl-D-aspartate in mice. Eur. J. Pharmacol. 219:477-479; 1992.
17. Minegishi, A.; Fukumori, R.; Satoh, T.; Kitagawa, H. Modulation of seizure pattern in the rat by neutral metabolites of indoleamines. J. Pharm. Pharmacol. 33:395-397; 1981.
18. Mollace, V.; Bagetta, G.; Nisticò, G. Evidence that L-arginine possesses proconvulsant effects mediated through nitric oxide. Neuroreport 2:269-272; 1991.
19. Penix, L. P.; Davis, W.; Subramaniam, S. Inhibition of NO synthase increases the severity of kainic acid-induced seizures in rodents. Epilepsy Res. 18:177-184; 1994.
20. Przegaliński, E.; Baran, L.; Siwanowicz, J. The role of nitric oxide in the kainate-induced seizures in mice. Neurosci. Lett. 170: 74-76; 1994.
21. Rondouin, G.; Bockaert, J.; Lerner-Natoli, M. L-Nitroarginine, an inhibitor of NO synthase, dramatically worsens limbic epilepsy in rats. Neuroreport 4:1187-1190; 1993.
22. Satoh, T.; Fukumori, R.; Nakagawa, I.; Minegishi, A.; Kitagawa, H.; Yanaura, S. Effect of tryptophol on pentylenetetrazol and picrotoxin induced convulsion in mice. Life Sci. 24:2031-2036; 1979.
23. Schuman, E. M.; Madison, D. V. Nitric oxide and synaptic function. Annu. Rev. Neurosci. 17:153-183; 1994.
24. Starr, M. S.; Starr, B. S. Paradoxical facilitation of pilocarpine-induced seizures in the mouse by MK-801 and the nitric oxide synthesis inhibitor L-NAME. Pharmacol. Biochem. Behav. 45: 321-325; 1993.
25. Tanaka, K.; Gotoh, F.; Gomi, S; Takashima, S.; Mihara, B.; Shirai, T.; Nogawa, S.; Nagata, E. Inhibition of nitric oxide synthesis induces a significant reduction in local cerebral blood flow in the rat. Neurosci. Lett. 127:129-132; 1991.
26. Vallebuona, F.; Raiteri, M. Monitoring of cyclic GMP during cerebellar microdialysis in freely-moving rats as an index of nitric oxide synthase activity. Neuroscience 57:577-585; 1993.
27. Weiss, L. R.; Nelson, J. W.; Tye, A. The facultative action of reserpine on metrazol convulsions when modified by iproniazid. J. Am. Pharm. Assoc. 49:514-517; 1960.
28. Wood, P. L. Pharmacology of the second messenger, cyclic guanosine 3′,5′-monophosphate, in the cerebellum. Pharmacol. Rev. 43:1-25; 1991.
29. Wood, P. L.; Ryan, R.; Li, M. Excitatory amino acid signal transduction in the hypocampus: Role of noradrenergic afferents and nitric oxide in cGMP increases in vivo. Life Sci. 51:601-606; 1992.
30. Yonekawa, W. D.; Kupferberg, H. J.; Woodbury, D. M. Relationship between pentylenetetrazol-induced seizures and brain pentylenetetrazol levels in mice. J. Pharmacol. Exp. Ther. 214: 589-593; 1980.