메뉴 건너뛰기




Volumn 102, Issue 1-2, 1996, Pages 159-165

N-Ethyl-N-nitrosourea induces mammary cancers in the pituitary-isografted mouse which are histologically and genotypically distinct from those induced by N-methyl-N-nitrosourea

Author keywords

Mammary tumorigenesis; Mouse; N ethyl n nitrosourea; Pituitary isograft

Indexed keywords

CARCINOGEN; ETHYLNITROSOUREA;

EID: 0029670233     PISSN: 03043835     EISSN: None     Source Type: Journal    
DOI: 10.1016/0304-3835(96)04175-4     Document Type: Article
Times cited : (12)

References (29)
  • 2
    • 0021085571 scopus 로고
    • Alkylation of isolated chromatin with N-methyl-N-nitrosourea and N-ethyl-N-nitrosourea
    • Marushige, K. and Marushige, Y. (1983) Alkylation of isolated chromatin with N-methyl-N-nitrosourea and N-ethyl-N-nitrosourea. Chem.-Biol. Interact., 46, 165-177.
    • (1983) Chem.-Biol. Interact. , vol.46 , pp. 165-177
    • Marushige, K.1    Marushige, Y.2
  • 3
    • 0039333555 scopus 로고
    • DNA base changes and alkylation following in vivo exposure of Escherichia coli to N-methyl-N-nitrosourea or N-ethyl-N-nitrosourea
    • Richardson, K.K., Richardson, F.C., Crosby, R.M., Swenberg, J.A. and Skopek, T.R. (1987) DNA base changes and alkylation following in vivo exposure of Escherichia coli to N-methyl-N-nitrosourea or N-ethyl-N-nitrosourea. Proc. Natl. Acad. Sci. USA, 84, 344-348.
    • (1987) Proc. Natl. Acad. Sci. USA , vol.84 , pp. 344-348
    • Richardson, K.K.1    Richardson, F.C.2    Crosby, R.M.3    Swenberg, J.A.4    Skopek, T.R.5
  • 4
    • 0018725475 scopus 로고
    • Relationship between DNA alkylation and specific-locus mutation induction by N-methyl-N-nitrosourea in cultured Chinese Hamster ovary cells (CHO/HGPRT system)
    • Theilmann, H.W., Schroder, C.H., O'Neill, J.P., Brimer, P.A. and Hsie, A.W. (1979) Relationship between DNA alkylation and specific-locus mutation induction by N-methyl-N-nitrosourea in cultured Chinese Hamster ovary cells (CHO/HGPRT system). Chem.-Biol. Interact., 26, 233-243.
    • (1979) Chem.-Biol. Interact. , vol.26 , pp. 233-243
    • Theilmann, H.W.1    Schroder, C.H.2    O'Neill, J.P.3    Brimer, P.A.4    Hsie, A.W.5
  • 5
    • 0023794744 scopus 로고
    • Formation and removal of DNA adducts after treatment of Chinese hamster ovary cells with N-methyl-and N-ethyl-N-nitrosourea
    • Theilmann, H.W., Schroder, C.H. and Hsie, A.W. (1988) Formation and removal of DNA adducts after treatment of Chinese hamster ovary cells with N-methyl-and N-ethyl-N-nitrosourea. Mutat. Res., 202, 235-250.
    • (1988) Mutat. Res. , vol.202 , pp. 235-250
    • Theilmann, H.W.1    Schroder, C.H.2    Hsie, A.W.3
  • 6
    • 0019515655 scopus 로고
    • Carcinogenicity of N-methyl-N-nitrosourea and N-ethyl-N-nitrosourea when applied to a localized area of the hamster trachea
    • Grubbs, C.J., Becci, P.J., Thompson, H.J. and Moon, R.C. (1981) Carcinogenicity of N-methyl-N-nitrosourea and N-ethyl-N-nitrosourea when applied to a localized area of the hamster trachea. J. Natl. Cancer Inst, 66, 961-965.
    • (1981) J. Natl. Cancer Inst , vol.66 , pp. 961-965
    • Grubbs, C.J.1    Becci, P.J.2    Thompson, H.J.3    Moon, R.C.4
  • 7
    • 0014027572 scopus 로고
    • Teratogenic and carcinogenic effects in the offspring after a single injection of ethylnitrosourea to pregnant rats
    • Druckrey, H., Ivankovic, S. and Preussmann, R. (1966) Teratogenic and carcinogenic effects in the offspring after a single injection of ethylnitrosourea to pregnant rats. Nature, 210, 1378-1379.
    • (1966) Nature , vol.210 , pp. 1378-1379
    • Druckrey, H.1    Ivankovic, S.2    Preussmann, R.3
  • 8
    • 0025351626 scopus 로고
    • Characterization of N-nitrosoureainduced tumors of the nervous system: Their prospective value for studies of neurogenesis and brain tumor therapy
    • Koestner, A. (1990) Characterization of N-nitrosoureainduced tumors of the nervous system: their prospective value for studies of neurogenesis and brain tumor therapy. Tox. Pathol., 18.
    • (1990) Tox. Pathol. , vol.18
    • Koestner, A.1
  • 9
    • 0015256458 scopus 로고
    • The induction of tumors of the nervous system with intravenous methylnitrosourea
    • Swenberg, J.A., Koestner, A. and Wechsler, W. (1972) The induction of tumors of the nervous system with intravenous methylnitrosourea. Lab. Invest., 26, 74-85.
    • (1972) Lab. Invest. , vol.26 , pp. 74-85
    • Swenberg, J.A.1    Koestner, A.2    Wechsler, W.3
  • 10
    • 0015040129 scopus 로고
    • Transplacental production with ethylnitrosourea of neoplasms of the nervous system in Sprague-Dawley rats
    • Koestner, A., Swenberg, J.A. and Wechsler, W. (1970) Transplacental production with ethylnitrosourea of neoplasms of the nervous system in Sprague-Dawley rats. Am. J. Pathol., 63, 37-56.
    • (1970) Am. J. Pathol. , vol.63 , pp. 37-56
    • Koestner, A.1    Swenberg, J.A.2    Wechsler, W.3
  • 11
    • 0022004418 scopus 로고
    • Host factors affecting the growth of carcinogen-induced rat mammary carcinomas: A review and tribute to Charles Brenton Huggins
    • Welsch, C.W. (1985) Host factors affecting the growth of carcinogen-induced rat mammary carcinomas: a review and tribute to Charles Brenton Huggins. Cancer Res., 45, 3415-3443.
    • (1985) Cancer Res. , vol.45 , pp. 3415-3443
    • Welsch, C.W.1
  • 12
    • 0020675737 scopus 로고
    • Characterization of N-ethyl-N-nitrosourea-induced mammary tumors in the rat
    • Stoica, G., Koestner, A. and Capen, C.C. (1983) Characterization of N-ethyl-N-nitrosourea-induced mammary tumors in the rat. Am. J. Pathol., 110, 161-169.
    • (1983) Am. J. Pathol. , vol.110 , pp. 161-169
    • Stoica, G.1    Koestner, A.2    Capen, C.C.3
  • 13
    • 0021253567 scopus 로고
    • Neoplasms induced with high single doses of N-ethyl-N-nitrosourea in 30-day-old Sprague-Dawley rats
    • Stoica, G., Koestner, A. and Capen, C.C. (1984) Neoplasms induced with high single doses of N-ethyl-N-nitrosourea in 30-day-old Sprague-Dawley rats. Anticancer Res., 4, 5-12.
    • (1984) Anticancer Res. , vol.4 , pp. 5-12
    • Stoica, G.1    Koestner, A.2    Capen, C.C.3
  • 14
    • 0028177712 scopus 로고
    • Evaluation of potential oncogene alterations in the ENU1564 rat mammary tumor model
    • Hal, D.G. and Stoica, G. (1994) Evaluation of potential oncogene alterations in the ENU1564 rat mammary tumor model. Anticancer Res., 14, 481-488.
    • (1994) Anticancer Res. , vol.14 , pp. 481-488
    • Hal, D.G.1    Stoica, G.2
  • 15
    • 0022255609 scopus 로고
    • Carcinogenic responses to chemicals applied directly to rat mammary glands in situ
    • Holtzman, S., Meade, M., Stone, J.P. and Shellabarger, C.J. (1985) Carcinogenic responses to chemicals applied directly to rat mammary glands in situ. Carcinogenesis, 6, 769-772.
    • (1985) Carcinogenesis , vol.6 , pp. 769-772
    • Holtzman, S.1    Meade, M.2    Stone, J.P.3    Shellabarger, C.J.4
  • 16
    • 0026671284 scopus 로고
    • Incidence of c-Ki-ras activation in N-methyl-N-nitrosourea-induced mammary carcinomas in pituitary-isografted mice
    • Guzman, R.C., Osborn, R.C., Swanson, S.M., Sakthivel, R., Hwang, S.-I., Miyamoto, S. and Nandi, S. (1992) Incidence of c-Ki-ras activation in N-methyl-N-nitrosourea-induced mammary carcinomas in pituitary-isografted mice. Cancer Res., 52, 5732-5737.
    • (1992) Cancer Res. , vol.52 , pp. 5732-5737
    • Guzman, R.C.1    Osborn, R.C.2    Swanson, S.M.3    Sakthivel, R.4    Hwang, S.-I.5    Miyamoto, S.6    Nandi, S.7
  • 17
    • 0002494370 scopus 로고
    • Morphology of mammary tumors in mice
    • Editor: F. Homburger. Paul B. Hoeber, New York
    • Dunn, T.B. (1959) Morphology of mammary tumors in mice. In: The Physiopathology of Cancer, pp. 38-84. Editor: F. Homburger. Paul B. Hoeber, New York.
    • (1959) The Physiopathology of Cancer , pp. 38-84
    • Dunn, T.B.1
  • 18
    • 0016253027 scopus 로고
    • Mammary tumorigenesis in chemical carcinogen-treated mice. II. Dependence on hormone stimulation for tumorigenesis
    • Medina, D. (1974) Mammary tumorigenesis in chemical carcinogen-treated mice. II. Dependence on hormone stimulation for tumorigenesis. J. Natl. Cancer Inst., 53, 223-226.
    • (1974) J. Natl. Cancer Inst. , vol.53 , pp. 223-226
    • Medina, D.1
  • 19
    • 0021795976 scopus 로고
    • Ectopic pituitary grafts in mice: Hormone levels, effects on fertility, and the development of adenomyosis uteri, prolactinomas, and mammary carcinomas
    • Huseby, R.A., Scares, M.J. and Talamantes, F. (1985) Ectopic pituitary grafts in mice: Hormone levels, effects on fertility, and the development of adenomyosis uteri, prolactinomas, and mammary carcinomas. Endocrinology, 116, 1440-1448.
    • (1985) Endocrinology , vol.116 , pp. 1440-1448
    • Huseby, R.A.1    Scares, M.J.2    Talamantes, F.3
  • 20
    • 0000457381 scopus 로고
    • Preparation of genomic DNA from mammalian tissues
    • Editors: F.M. Ausubel, R. Brent, R.E. Kingston, R.E. Moore, J.G. Seidman, J.A. Smith and K. Struhl. Wiley, New York
    • Stauss, W.M. (1995) Preparation of genomic DNA from mammalian tissues. In: Current Protocols in Molecular Biology, pp. 2.2.1-2.2.3. Editors: F.M. Ausubel, R. Brent, R.E. Kingston, R.E. Moore, J.G. Seidman, J.A. Smith and K. Struhl. Wiley, New York.
    • (1995) Current Protocols in Molecular Biology , pp. 221-223
    • Stauss, W.M.1
  • 22
    • 0022065447 scopus 로고
    • Structure and expression of amplified c-Ki-ras gene sequences in Y1 mouse adrenal tumor cells
    • George, D.L., Scott, A.F., Trussko, S., Blick, B., Ford, E. and Dorney, D.J. (1985) Structure and expression of amplified c-Ki-ras gene sequences in Y1 mouse adrenal tumor cells. EMBO J., 4, 1199-1203.
    • (1985) EMBO J. , vol.4 , pp. 1199-1203
    • George, D.L.1    Scott, A.F.2    Trussko, S.3    Blick, B.4    Ford, E.5    Dorney, D.J.6
  • 23
    • 0024271510 scopus 로고
    • Isolation and characterization of the 5′ flanking region of the mouse c-Harvey-ras gene
    • Brown, K., Bailleul, B., Ramsden, M., Fee, F., Krumlauf, R. and Balmain, A. (1988) Isolation and characterization of the 5′ flanking region of the mouse c-Harvey-ras gene. Mol. Carcinogen., 1, 161-70.
    • (1988) Mol. Carcinogen. , vol.1 , pp. 161-170
    • Brown, K.1    Bailleul, B.2    Ramsden, M.3    Fee, F.4    Krumlauf, R.5    Balmain, A.6
  • 25
    • 0039045336 scopus 로고
    • Hormone-dependent activation of K.-ras in N-methyl-N-nitrosourea (MNU)-induced mouse mammary tumors
    • Editors: J. Li, S. Nandi and S.A. Li. SpringerVerlag, New York
    • Guzman, R.C., Osborn, R.C., Miyamoto, S., Sakthivel, R., Hwang, S. and Nandi, S. (1992) Hormone-dependent activation of K.-ras in N-methyl-N-nitrosourea (MNU)-induced mouse mammary tumors. In: Hormonal Carcinogenesis, pp. 299-301. Editors: J. Li, S. Nandi and S.A. Li. SpringerVerlag, New York.
    • (1992) Hormonal Carcinogenesis , pp. 299-301
    • Guzman, R.C.1    Osborn, R.C.2    Miyamoto, S.3    Sakthivel, R.4    Hwang, S.5    Nandi, S.6
  • 26
    • 0028284687 scopus 로고
    • Pituitary-isografted mice are highly susceptible to MNU-induced mammary Carcinogenesis irrespective of the level of alveolar differentiation
    • Swanson, S.M., Guzman, R.C., Christov, K., Miyamoto, S. and Nandi, S. (1994) Pituitary-isografted mice are highly susceptible to MNU-induced mammary Carcinogenesis irrespective of the level of alveolar differentiation. Carcinogenesis, 15, 1341-1346.
    • (1994) Carcinogenesis , vol.15 , pp. 1341-1346
    • Swanson, S.M.1    Guzman, R.C.2    Christov, K.3    Miyamoto, S.4    Nandi, S.5
  • 27
    • 0026644013 scopus 로고
    • Mutagenesis of the K.-ras protooncogene in mouse lung tumors induced by N-ethyl-N-nitrosourea or N-nitrosodiethylamine
    • You, M., Wang, Y., Lineen, A.M., Gunning, W.T., Stoner, G.D. and Anderson, M.W. (1992) Mutagenesis of the K.-ras protooncogene in mouse lung tumors induced by N-ethyl-N-nitrosourea or N-nitrosodiethylamine. Carcinogenesis, 13, 1583-1586.
    • (1992) Carcinogenesis , vol.13 , pp. 1583-1586
    • You, M.1    Wang, Y.2    Lineen, A.M.3    Gunning, W.T.4    Stoner, G.D.5    Anderson, M.W.6
  • 28
    • 0026092941 scopus 로고
    • Mutational activation of the c-Ha-ras gene in liver tumors of different rodent strains: Correlation with susceptibility to hepatocarcinogenesis
    • Buchmann, A., Bauer-Hofmann, R., Mahr, J., Drinkwater, N.R., Luz, A. and Schwarz, M. (1991) Mutational activation of the c-Ha-ras gene in liver tumors of different rodent strains: correlation with susceptibility to hepatocarcinogenesis. Proc. Natl. Acad. Sci. USA, 88, 911-915.
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 911-915
    • Buchmann, A.1    Bauer-Hofmann, R.2    Mahr, J.3    Drinkwater, N.R.4    Luz, A.5    Schwarz, M.6
  • 29
    • 0029024185 scopus 로고
    • Refractoryness to mammary carcinogenesis in the parous mouse is reversible by hormonal stimulation induced by pituitary isografts
    • Swanson, S.M., Guzman, R.C., Collins, G., Tafoya, P., Thordarson, G., Talamantes, F. and Nandi, S. (1995) Refractoryness to mammary carcinogenesis in the parous mouse is reversible by hormonal stimulation induced by pituitary isografts. Cancer Lett., 90, 171-181.
    • (1995) Cancer Lett. , vol.90 , pp. 171-181
    • Swanson, S.M.1    Guzman, R.C.2    Collins, G.3    Tafoya, P.4    Thordarson, G.5    Talamantes, F.6    Nandi, S.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.