Multiple, coordinated Ca2+-release events underlie the inositol trisphosphate-induced local Ca2+ spikes in mouse pancreatic acinar cells

EMBO Journal

Volumn 15, Issue 5, 1996, Pages 999-1003

  Thorn, Peter ^b   Moreton, Roger ^a   Berridge, Michael ^a  

^a Department of Zoology   (United Kingdom)

^b BABRAHAM INSTITUTE   (United Kingdom)

Author keywords

Calcium signalling; InsP3; Pancreatic acinar cells

Indexed keywords

CALCIUM; INOSITOL 1,4,5 TRISPHOSPHATE;

ANIMAL; ARTICLE; BINDING SITE; CYTOLOGY; DRUG EFFECT; ELECTROPHYSIOLOGY; IN VITRO STUDY; INTRACELLULAR FLUID; METABOLISM; MOUSE; PANCREAS; PHYSIOLOGY; SIGNAL TRANSDUCTION; ACINAR CELL; ANIMAL CELL; CALCIUM TRANSPORT; CONTROLLED STUDY; IMAGING; MOLECULAR MODEL; NONHUMAN; PRIORITY JOURNAL; SPIKE;

ANIMALS; BINDING SITES; CALCIUM; ELECTROPHYSIOLOGY; INOSITOL 1,4,5-TRISPHOSPHATE; INTRACELLULAR FLUID; MICE; PANCREAS; SIGNAL TRANSDUCTION;

ANIMALIA;

EID: 0029670219     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1002/j.1460-2075.1996.tb00436.x     Document Type: Article

References (18)

1. Berridge, M.J. (1993) Inositol trisphosphate and calcium signalling. Nature, 361, 315-325.
2. 2+ stores. J. Biol. Chem , 269, 24783-24791.
3. Camacho, P. and Lechleiter, J.D. (1993) Increased frequency of calcium waves in Xenupus laevis oocytes that express a calcium-ATPase. Science, 260, 226-229.
4. 2+ entry in bovine adrenal chromaffin cells: different patterns induced by histamine and angiotensrn II and relationship to catecholamine release. J. Cell Sci , 109, 913-921.
5. Cheung, H., Lederer, W.J. and Cannell, M.B. (1993) Calcium sparks: elementary events underlying excitation-contraction coupling in heart muscle. Science, 262, 740-744.
6. Hamill, O.P., Marty, A., Neher, E., Sakmann, B. and Sigworth, F.J. (1981) Improved patch clamp techniques for high resolution current recording from cells and cell-free membrane patches. Pflugers Arch., 391, 85-100.
7. 2+ gradients triggering unidirectional fluid secretion from exocrine pancreas. Nature, 348, 735-738.
8. 2+ waves and oscillations in exocrine pancreas. Cell, 74, 669-667.
9. Muallem, S., Pandol, S.J. and Beeker, T.G. (1989) Hormone-evoked calcium release from intracellular stores is a quantal process. J. Biol. Chem., 246, 205-212.
10. 2+ wave propagation in pancreatic acinar cells. J. Biol. Chem., 267, 18118-18121.
11. Nelson, M.T., Cheng, H., Rubart, M., Santana, L.F., Bonev, A., Knot, A. and Lederer, W.J. (1995) Relaxation of arterial smooth muscle by calcium sparks. Science, 270, 633-637.
12. Petersen, O H. (1992) Stimulus secretion coupling: cytoplasmic calcium signals and control of ion channels in exocrine acinar cells. J. Physiol., 448, 1-51.
13. Petersen, C.C.H., Petersen, O H. and Berridge, M.J. (1993) The role of endoplasmic reticulum calcium pumps during cytosolic calcium spiking in pancreatic acinar cells. J. Biol. Chem., 268, 22262-22264.
14. 2+ oscillations in exocrine cells evoked by agonists and inositol trisphosphate. Cell, 74, 661-668.
15. 2+ oscillations in pancreatic acinar cells. EMBO J., 13, 2038-2043.
16. 2+ release by inositol 1,4,5-trisphosphate in permeabilized pancreatic acinar cells. J. Biol. Chem., 269, 12438-12443.
17. Wakui, M., Potter, B.V.L. and Petersen, O H. (1989) Pulsatile intracellular calcium release does not depend on fluctuations in inositol trisphosphate concentration. Nature, 339, 317-320.
18. 2+ evoked by inositol trisphosphate in Xenopus oocytes. J. Physiol., 482.3, 533-553.