메뉴 건너뛰기




Volumn 23, Issue 2, 1996, Pages 141-146

In vivo evaluation of [11C]- and [18F]-labelled cocaine analogues as potential dopamine transporter ligands for positron emission tomography

Author keywords

Analogue; C 11; Cocaine; Dopamine transporter; F 18; Positron emission tomography

Indexed keywords

CARBON 11; COCAINE; COCAINE DERIVATIVE; DESIPRAMINE; FLUORINE 18; FLUOXETINE; SPIPERONE; 2' FLUOROETHYL 8 METHYL 3 (4 CHLOROPHENYL) 8 AZABICYCLO(3.2.1)OCTANE 2 CARBOXYLATE; 2' FLUOROETHYL 8 METHYL 3 (4 METHYLPHENYL) 8 AZABICYCLO(3.2.1)OCTANE 2 CARBOXYLATE; 2'-FLUOROETHYL 8-METHYL-3-(4-CHLOROPHENYL)-8-AZABICYCLO(3.2.1)OCTANE-2-CARBOXYLATE; 2'-FLUOROETHYL 8-METHYL-3-(4-METHYLPHENYL)-8-AZABICYCLO(3.2.1)OCTANE-2-CARBOXYLATE; CARBON; CARRIER PROTEIN; DIAGNOSTIC AGENT; DOPAMINE TRANSPORTER; DRUG DERIVATIVE; FLUORINE; LIGAND; MEMBRANE PROTEIN; NERVE PROTEIN; RTI COC 32; RTI-COC 32;

EID: 0029670103     PISSN: 09698051     EISSN: None     Source Type: Journal    
DOI: 10.1016/0969-8051(95)02044-6     Document Type: Article
Times cited : (69)

References (33)
  • 3
    • 0024460030 scopus 로고
    • Effects of cocaine and related drugs in nonhuman primates. III. Self-administration by squirrel monkeys
    • Bergman, J., Madras, B. K., Johnson, S. E., and Spealman, R. D. (1989) Effects of Cocaine and Related Drugs in Nonhuman Primates. III. Self-administration by Squirrel Monkeys. J. Pharmacol. Exp. Ther. 251, 150.
    • (1989) J. Pharmacol. Exp. Ther. , vol.251 , pp. 150
    • Bergman, J.1    Madras, B.K.2    Johnson, S.E.3    Spealman, R.D.4
  • 4
    • 0027516578 scopus 로고
    • Functional imaging in relation to Parkinsonian syndromes
    • Brooks, D. J. (1993) Functional Imaging in Relation to Parkinsonian Syndromes. J. Neurolog. Sci. 115, 1.
    • (1993) J. Neurolog. Sci. , vol.115 , pp. 1
    • Brooks, D.J.1
  • 5
    • 0025065388 scopus 로고
    • Differing patterns of striatal F-18-dopa uptake in Parkinson's disease, multiple system atrophy, and progressive supranuclear palsy
    • Brooks, D. J., Ibanez, V., Sawle, G. V., Quinn, N., Lees, A. J., Mathias, C. J., Bannister, R., Marsden, C. D., and Frackowiak, R. (1990) Differing Patterns of Striatal F-18-dopa Uptake in Parkinson's Disease, Multiple System Atrophy, and Progressive Supranuclear Palsy. Ann. Neurol. 28, 547.
    • (1990) Ann. Neurol. , vol.28 , pp. 547
    • Brooks, D.J.1    Ibanez, V.2    Sawle, G.V.3    Quinn, N.4    Lees, A.J.5    Mathias, C.J.6    Bannister, R.7    Marsden, C.D.8    Frackowiak, R.9
  • 6
    • 0026647629 scopus 로고
    • Isopropyl and phenyl esters of 3β-(4-substitutedphenyl)tropan-2β-carboxylic acids. Potent and selective compounds for the dopamine transporter
    • Carroll, F. I., Abraham, P., Lewin, A. H., Parham, K. A., Boja, J. W., and Kuhar, M. J. (1992a) Isopropyl and Phenyl Esters of 3β-(4-Substitutedphenyl)tropan-2β-carboxylic Acids. Potent and Selective Compounds for the Dopamine Transporter. J. Med. Chem. 35, 2497.
    • (1992) J. Med. Chem. , vol.35 , pp. 2497
    • Carroll, F.I.1    Abraham, P.2    Lewin, A.H.3    Parham, K.A.4    Boja, J.W.5    Kuhar, M.J.6
  • 7
    • 0029063953 scopus 로고
    • Cocaine and 3β-(4′-substituted phenyl)tropane-2β-carboxylic acid ester and amide analogues. New high-affinity and selective compounds for the dopamine transporter
    • Carroll, F. I., Kotian, P., Dehghani, A., Gray, J. L., Kuzemko, M. A., Parham, K. A., Abraham, P., Lewin, A. H., Boja, J. W., and Kuhar, M. J. (1995) Cocaine and 3β-(4′-Substituted phenyl)tropane-2β-carboxylic Acid Ester and Amide Analogues. New High-Affinity and Selective Compounds for the Dopamine Transporter. J. Med. Chem. 38, 379.
    • (1995) J. Med. Chem. , vol.38 , pp. 379
    • Carroll, F.I.1    Kotian, P.2    Dehghani, A.3    Gray, J.L.4    Kuzemko, M.A.5    Parham, K.A.6    Abraham, P.7    Lewin, A.H.8    Boja, J.W.9    Kuhar, M.J.10
  • 8
    • 0026566383 scopus 로고
    • Cocaine receptor: Biochemical characterization and structure-activity relationships of cocaine analogues at the dopamine transporter
    • Carroll, F. I., Lewin, A. H., Boja, J. W., and Kuhar, M. J. (1992b) Cocaine Receptor: Biochemical Characterization and Structure-Activity Relationships of Cocaine Analogues at the Dopamine Transporter. J. Med. Chem. 35, 969.
    • (1992) J. Med. Chem. , vol.35 , pp. 969
    • Carroll, F.I.1    Lewin, A.H.2    Boja, J.W.3    Kuhar, M.J.4
  • 9
    • 0027968806 scopus 로고
    • Synthesis, ligand binding, and QSAR (CoMFA and classical) study of 3 β-(3′-substituted phenyl)-, 3 β-(4′-substituted phenyl)-, and 3 β-(3′,4′-disubstituted phenyl)tropane-2β-carboxylic acid methyl esters
    • Carroll, F. I., Mascarella, S. W., Kuzemko, M. A., Gao, Y. G., Abraham, P., Lewin, A. H., Boja, J. W., and Kuhar, M. J. (1994) Synthesis, ligand binding, and QSAR (CoMFA and classical) study of 3 β-(3′-substituted phenyl)-, 3 β-(4′-substituted phenyl)-, and 3 β-(3′,4′-disubstituted phenyl)tropane-2β-carboxylic acid methyl esters. J. Med. Chem. 37, 2865.
    • (1994) J. Med. Chem. , vol.37 , pp. 2865
    • Carroll, F.I.1    Mascarella, S.W.2    Kuzemko, M.A.3    Gao, Y.G.4    Abraham, P.5    Lewin, A.H.6    Boja, J.W.7    Kuhar, M.J.8
  • 12
    • 0028237668 scopus 로고
    • Synthesis of 2 β-acyl-3 β-aryl-8-azabicyclo[3.2.1]octanes and their binding affinities at dopamine and serotonin transport sites in rat striatum and frontal cortex
    • Davies, H. M., Saikali, E., Huby, N., Gilliatt, V. J., Matasi, J. J., Sexton, T., and Childers, S. R. (1994) Synthesis of 2 β-Acyl-3 β-Aryl-8-Azabicyclo[3.2.1]octanes and their Binding Affinities at Dopamine and Serotonin Transport Sites in Rat Striatum and Frontal Cortex. J. Med. Chem. 37, 1262.
    • (1994) J. Med. Chem. , vol.37 , pp. 1262
    • Davies, H.M.1    Saikali, E.2    Huby, N.3    Gilliatt, V.J.4    Matasi, J.J.5    Sexton, T.6    Childers, S.R.7
  • 13
    • 0028178856 scopus 로고
    • PET study of [C-11]β-CIT binding to monoamine transporters in the monkey and human brain
    • Farde, L., Halldin, C., Muller, L., Suhara, T., Karlsson, P., and Hall, H. (1994) PET Study of [C-11]β-CIT Binding to Monoamine Transporters in the Monkey and Human Brain. Synapse 16, 93.
    • (1994) Synapse , vol.16 , pp. 93
    • Farde, L.1    Halldin, C.2    Muller, L.3    Suhara, T.4    Karlsson, P.5    Hall, H.6
  • 16
    • 0027296568 scopus 로고
    • Positron emission tomographic imaging of the dopamine transporter with C-11-win 35,428 reveals marked declines in mild Parkinsons disease
    • Frost, J. J., Rosier, A. J., Reich, S. G., Smith, J. S., Ehlers, M. D., Snyder, S. H., Ravert, H. T., and Dannals, R. F. (1993) Positron Emission Tomographic Imaging of the Dopamine Transporter with C-11-Win 35,428 Reveals Marked Declines in Mild Parkinsons Disease. Ann. Neur. 34, 423.
    • (1993) Ann. Neur. , vol.34 , pp. 423
    • Frost, J.J.1    Rosier, A.J.2    Reich, S.G.3    Smith, J.S.4    Ehlers, M.D.5    Snyder, S.H.6    Ravert, H.T.7    Dannals, R.F.8
  • 18
    • 0028337480 scopus 로고
    • Synthesis and characterization of radioiodinated N-(3-iodopropen-1-yl)-2β-carbomethoxy-3β-(4-chlorophenyl)tropanes: Potential dopamine reuptake site imaging agents
    • Goodman, M. M., Kung, M.-P., Kabalka, G. W., Kung, H. F., and Switzer, R. (1994) Synthesis and Characterization of Radioiodinated N-(3-Iodopropen-1-yl)-2β-carbomethoxy-3β-(4-chlorophenyl)tropanes: Potential Dopamine Reuptake Site Imaging Agents. J. Med. Chem. 37, 1535.
    • (1994) J. Med. Chem. , vol.37 , pp. 1535
    • Goodman, M.M.1    Kung, M.-P.2    Kabalka, G.W.3    Kung, H.F.4    Switzer, R.5
  • 19
    • 0021127531 scopus 로고
    • Behavioral properties of GBR 12909, GBR 13069 and GBR 13098: Specific inhibitors of dopamine uptake
    • Heikkila, R., and Manzino, L. (1984) Behavioral Properties of GBR 12909, GBR 13069 and GBR 13098: Specific Inhibitors of Dopamine Uptake. Eur. J. Pharmacol. 103, 241.
    • (1984) Eur. J. Pharmacol. , vol.103 , pp. 241
    • Heikkila, R.1    Manzino, L.2
  • 20
    • 0027979323 scopus 로고
    • Molecular, functional and biochemical characteristics of the dopamine transporter-regional differences and clinical relevance
    • Hitri, A., Hurd, Y. L., Wyatt, R. J., and Deutsch, S. I. (1994) Molecular, Functional and Biochemical Characteristics of the Dopamine Transporter-Regional Differences and Clinical Relevance. Clin. Neuropharmacol. 17, 1.
    • (1994) Clin. Neuropharmacol. , vol.17 , pp. 1
    • Hitri, A.1    Hurd, Y.L.2    Wyatt, R.J.3    Deutsch, S.I.4
  • 23
    • 0026775763 scopus 로고
    • Role of the dopaminergic system in depression
    • Kapur, S., and Mann, J. J. (1992) Role of the Dopaminergic System in Depression. Biol. Psychiatry 32, 1.
    • (1992) Biol. Psychiatry , vol.32 , pp. 1
    • Kapur, S.1    Mann, J.J.2
  • 27
    • 0028241283 scopus 로고
    • N-ω-fluoroalkyl analogs of (1R)-2β-carbomethoxy-3β-(4-iodophenyl)-tropane (β-CIT): Radiotracers for positron emission tomography and single photon emission computed tomography imaging of dopamine transporters
    • Neumeyer, J. L., Wang, S., Gao, Y., Milius, R., Kula, N. S., Campbell, A., Baldessarin, R. J., Zea-Ponce, Y., Baldwin, R. M., and Innis, R. M. (1994) N-ω-Fluoroalkyl Analogs of (1R)-2β-Carbomethoxy-3β-(4-iodophenyl)-tropane (β-CIT): Radiotracers for Positron Emission Tomography and Single Photon Emission Computed Tomography Imaging of Dopamine Transporters. J. Med. Chem. 37, 1558.
    • (1994) J. Med. Chem. , vol.37 , pp. 1558
    • Neumeyer, J.L.1    Wang, S.2    Gao, Y.3    Milius, R.4    Kula, N.S.5    Campbell, A.6    Baldessarin, R.J.7    Zea-Ponce, Y.8    Baldwin, R.M.9    Innis, R.M.10
  • 29
    • 0028343801 scopus 로고
    • Occupancy of the serotonin transporter by fluoxetine, paroxetine, and sertraline - In vivo studies with [I-125]RTI-55
    • Scheffel, U., Kim, S., Cline, E. J., and Kuhar, M. J. (1994) Occupancy of the Serotonin Transporter by Fluoxetine, Paroxetine, and Sertraline - In vivo Studies with [I-125]RTI-55. Synapse 16, 263.
    • (1994) Synapse , vol.16 , pp. 263
    • Scheffel, U.1    Kim, S.2    Cline, E.J.3    Kuhar, M.J.4
  • 30
    • 0025899393 scopus 로고
    • In vivo labeling of cocaine binding sites on dopamine transporter with [3H]WIN 35,428
    • Scheffel, U., Pögün, S., Stathis, M., Boja, J., and Kuhar, M. J. (1991) In Vivo Labeling of Cocaine Binding Sites on Dopamine Transporter with [3H]WIN 35,428. J. Pharmacol. Exp. Ther. 257, 954.
    • (1991) J. Pharmacol. Exp. Ther. , vol.257 , pp. 954
    • Scheffel, U.1    Pögün, S.2    Stathis, M.3    Boja, J.4    Kuhar, M.J.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.