Thromboxane A2-mediated shape change: Independent of Gq-phospholipase C-Ca2+ pathway in rabbit platelets

British Journal of Pharmacology

Volumn 117, Issue 6, 1996, Pages 1095-1104

  Ohkubo, Satoko ^a   Nakahata, Norimichi ^a   Ohizumi, Yasushi ^a  

^a TOHOKU UNIVERSITY   (Japan)

Author keywords

Ca2+; Gq; GTPase; ONO NT 126; Phospholipase C; Platelet aggregation; Platelet shape change; Thromboxane A2; Thromboxane A2 receptor; U46619

Indexed keywords

15 HYDROXY 11ALPHA,9ALPHA EPOXYMETHANOPROSTA 5,13 DIENOIC ACID; BICYCLO COMPOUND; CALCIUM; DRUG DERIVATIVE; GUANOSINE TRIPHOSPHATASE; MONOUNSATURATED FATTY ACID; ONO NT 126; ONO-NT 126; PHOSPHATIDYLINOSITOL; PHOSPHOLIPASE C; PROSTAGLANDIN ENDOPEROXIDE; THROMBOXANE A2; THROMBOXANE RECEPTOR; VASOCONSTRICTOR AGENT; 7 [3 [(4 PHENYLSEMICARBAZIDO)METHYL] 7 OXABICYCLO[2.2.1]HEPT 2 YL] 5 HEPTENOIC ACID; ANTIBODY; CALCIUM ION; GUANINE NUCLEOTIDE BINDING PROTEIN; PHOSPHATIDYLINOSITIDE; THROMBOXANE A2 RECEPTOR; THROMBOXANE A2 RECEPTOR BLOCKING AGENT; THROMBOXANE RECEPTOR STIMULATING AGENT; TRITIUM; VAPIPROST;

ANIMAL; ARTICLE; CELL SIZE; COMPARATIVE STUDY; CYTOLOGY; DOSE RESPONSE; DRUG ANTAGONISM; DRUG EFFECT; IN VITRO STUDY; MALE; METABOLISM; RABBIT; SIGNAL TRANSDUCTION; THROMBOCYTE; THROMBOCYTE AGGREGATION; ANIMAL CELL; CALCIUM CELL LEVEL; CALCIUM MOBILIZATION; CONTROLLED STUDY; ENZYME ACTIVATION; EXTRACELLULAR CALCIUM; HYDROLYSIS; ISOTOPE LABELING; LIGAND BINDING; NONHUMAN; PHOSPHOINOSITIDE METABOLISM; PRIORITY JOURNAL; THROMBOCYTE MEMBRANE; THROMBOCYTE SHAPE;

15-HYDROXY-11 ALPHA,9 ALPHA-(EPOXYMETHANO)PROSTA-5,13-DIENOIC ACID; ANIMALS; BICYCLO COMPOUNDS; BLOOD PLATELETS; CALCIUM; CELL SIZE; DOSE-RESPONSE RELATIONSHIP, DRUG; FATTY ACIDS, MONOUNSATURATED; GTP PHOSPHOHYDROLASES; MALE; PHOSPHATIDYLINOSITOLS; PHOSPHOLIPASE C; PLATELET AGGREGATION; PROSTAGLANDIN ENDOPEROXIDES, SYNTHETIC; RABBITS; RECEPTORS, THROMBOXANE; SIGNAL TRANSDUCTION; THROMBOXANE A2; VASOCONSTRICTOR AGENTS;

EID: 0029670064     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1476-5381.1996.tb16702.x     Document Type: Article

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