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Volumn 15, Issue 3, 1996, Pages 205-207

Poly (D,L-Lactide) glycolide polymer microsphere entrapped tetanus toxoid: Safety evaluation in Wistar rats

Author keywords

biodegradable polymer; tetanus toxoid; toxicity; vaccine

Indexed keywords

MICROSPHERE; POLYGLACTIN; POLYMER; TETANUS TOXOID;

EID: 0029669999     PISSN: 09603271     EISSN: None     Source Type: Journal    
DOI: 10.1177/096032719601500303     Document Type: Article
Times cited : (9)

References (14)
  • 1
    • 0019740466 scopus 로고
    • Polymer for the sustained release of macromolecules: Their use in a single step method of immunization
    • Langer R.; Polymer for the sustained release of macromolecules: Their use in a single step method of immunization. Methods Enzymol 1981 73: 56-75
    • (1981) Methods Enzymol , vol.73 , pp. 56-75
    • Langer, R.1
  • 2
    • 0023629924 scopus 로고
    • Opportunities and challenges in the design of implantable biodegradable polymeric systems for the delivery of antimicrobial agents and vaccines
    • Wise, DL; Opportunities and challenges in the design of implantable biodegradable polymeric systems for the delivery of antimicrobial agents and vaccines. Adv Drug Deliv Rev 1987 19-39
    • (1987) Adv Drug Deliv Rev , pp. 19-39
    • Wise, D.L.1
  • 3
    • 8044221875 scopus 로고
    • Developments of secretory and systemic immunity following oral administration of microencapsulated antigens
    • Gilley RM; Developments of secretory and systemic immunity following oral administration of microencapsulated antigens. Proc Int Symp Rel Bioact Mater 1988 15: 123-124
    • (1988) Proc Int Symp Rel Bioact Mater , vol.15 , pp. 123-124
    • Gilley, R.M.1
  • 4
    • 11944269392 scopus 로고
    • Controlled release of interleukin-2 from biodegradable microspheres
    • Hora MS; Controlled release of interleukin-2 from biodegradable microspheres. Biotechnology 1990 8: 755-758
    • (1990) Biotechnology , vol.8 , pp. 755-758
    • Hora, M.S.1
  • 5
    • 0025834747 scopus 로고
    • Biodegradable and biocompatible Poly (D,L-lactide-co-glycolide) microspheres as an adjuvant for Staphylococcal Enterotoxin B toxoid which enhances the level of toxin - neutralizing antibodies
    • Eldridge JH, Staas JK, Meulbroek JA, Tice TR and Gilley RM; Biodegradable and biocompatible Poly (D,L-lactide-co-glycolide) microspheres as an adjuvant for Staphylococcal Enterotoxin B toxoid which enhances the level of toxin - neutralizing antibodies. Infect Immunol 1991 59: 2978-2986
    • (1991) Infect Immunol , vol.59 , pp. 2978-2986
    • Eldridge, J.H.1    Staas, J.K.2    Meulbroek, J.A.3    Tice, T.R.4    Gilley, R.M.5
  • 6
    • 0018746463 scopus 로고
    • A single step immunization by sustained antigen release
    • Preis I. and Langer R.; A single step immunization by sustained antigen release. J. Immunol Methods 1979 28: 193-197
    • (1979) J. Immunol Methods , vol.28 , pp. 193-197
    • Preis, I.1    Langer, R.2
  • 7
    • 0022978022 scopus 로고
    • Single - step immunization using controlled release biodegradable polymer with sustained adjuvant activity
    • Kohn J., Niemi SM, Albert EC, Murphy JC, Langer R. and Fox J.; Single - step immunization using controlled release biodegradable polymer with sustained adjuvant activity. J. Immunol Methods 1986 95: 31-38
    • (1986) J. Immunol Methods , vol.95 , pp. 31-38
    • Kohn, J.1    Niemi, S.M.2    Albert, E.C.3    Murphy, J.C.4    Langer, R.5    Fox, J.6
  • 8
    • 0025730382 scopus 로고
    • Biodegradable microparticles as controlled release antigen delivery system
    • O'Hagan DT, Rahman D., Megee JP, Jeffery H., et al; Biodegradable microparticles as controlled release antigen delivery system. Immunology 1991 73: 239-244
    • (1991) Immunology , vol.73 , pp. 239-244
    • O'Hagan, D.T.1    Rahman, D.2    Megee, J.P.3    Jeffery, H.4
  • 9
    • 0025752856 scopus 로고
    • Controlled delivery of diphtheria toxoid using biodegradable poly (D,L-lactide) microcapsules
    • Singh M., Singh A. and Talwar GP; Controlled delivery of diphtheria toxoid using biodegradable poly (D,L-lactide) microcapsules. Pharmacol. Res. 1991 8: 958-961
    • (1991) Pharmacol. Res. , vol.8 , pp. 958-961
    • Singh, M.1    Singh, A.2    Talwar, G.P.3
  • 10
    • 0025069886 scopus 로고
    • Control vaccine release in the gut associated lymphokine tissue - 1 orally administered biodegradable microspheres target the Peyer's Patches
    • Eldbridge HJ, Hammad JC, Meulbroek JA, Stass JK, Gilley RM and Tice TR; Control vaccine release in the gut associated lymphokine tissue - 1 orally administered biodegradable microspheres target the Peyer's Patches. J. Control Red 1990 11: 205-214
    • (1990) J. Control Red , vol.11 , pp. 205-214
    • Eldbridge, H.J.1    Hammad, J.C.2    Meulbroek, J.A.3    Stass, J.K.4    Gilley, R.M.5    Tice, T.R.6
  • 11
    • 0026636415 scopus 로고
    • Parameters affecting the immunogenicity of microencapsulated tetanus toxoid
    • Esparza I. and Kissel T.; Parameters affecting the immunogenicity of microencapsulated tetanus toxoid. Vaccine 1992 10: 714-720
    • (1992) Vaccine , vol.10 , pp. 714-720
    • Esparza, I.1    Kissel, T.2
  • 12
    • 0025269767 scopus 로고
    • Subacute toxicity of adsorbed 250 Lf tetanus toxoid in rats
    • Sethi N., Singh RK and Srivastava RK; Subacute toxicity of adsorbed 250 Lf tetanus toxoid in rats. Indian J Exp Biol 1990a 28: 218-220
    • (1990) Indian J Exp Biol , vol.28 , pp. 218-220
    • Sethi, N.1    Singh, R.K.2    Srivastava, R.K.3
  • 13
    • 0025487501 scopus 로고
    • Safety evaluation of a potent tetanus toxoid (250Lf) in guinea-pigs. Biomed Environ
    • Sethi N., Srivastava RK, Singh RK and Srivastava S.; Safety evaluation of a potent tetanus toxoid (250Lf) in guinea-pigs. Biomed Environ Sci 1990 3: 364-371
    • (1990) Sci , vol.3 , pp. 364-371
    • Sethi, N.1    Srivastava, R.K.2    Singh, R.K.3    Srivastava, S.4
  • 14
    • 0028205133 scopus 로고
    • Biodegradable microspheres as controlled- release tetanus toxoid delivery systems
    • Alonso MJ, Gupta RK, Min C., Siber GR and Langer R.; Biodegradable microspheres as controlled- release tetanus toxoid delivery systems. Vaccine 1994 12: 299-306
    • (1994) Vaccine , vol.12 , pp. 299-306
    • Alonso, M.J.1    Gupta, R.K.2    Min, C.3    Siber, G.R.4    Langer, R.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.