The bioavailability of 26Al-labelled aluminium citrate and aluminium hydroxide in volunteers

BioMetals

Volumn 9, Issue 3, 1996, Pages 221-228

  Priest, N D ^a,d   Talbot, R J ^a   Austin, J G ^a   Day, J P ^b   King, S J ^b   Fifield, K ^c   Cresswell, R G ^c  

^a RICARDO UK LTD   (United Kingdom)

^b UNIVERSITY OF MANCHESTER   (United Kingdom)

^c AUSTRALIAN NATIONAL UNIVERSITY   (Australia)

^d MIDDLESEX UNIVERSITY   (United Kingdom)

Author keywords

Aluminium citrate; Aluminium hydroxide; Bioavailability; Ingestion

Indexed keywords

ALUMINUM; ALUMINUM CITRATE; ALUMINUM HYDROXIDE; CITRIC ACID; RADIOISOTOPE;

ARTICLE; BIOAVAILABILITY; BLOOD SAMPLING; CONTROLLED STUDY; FECES; FEEDING APPARATUS; GASTROINTESTINAL ABSORPTION; HUMAN; HUMAN EXPERIMENT; ISOTOPE LABELING; MALE; MASS SPECTROMETRY; NORMAL HUMAN; URINARY EXCRETION; VOLUNTEER; ADULT; CHEMISTRY; INTESTINE; INTESTINE ABSORPTION; METABOLISM; PHYSIOLOGY; REFERENCE VALUE;

ADULT; ALUMINUM; ALUMINUM HYDROXIDE; BIOLOGICAL AVAILABILITY; CITRATES; CITRIC ACID; FECES; HUMANS; INTESTINAL ABSORPTION; INTESTINES; MALE; RADIOISOTOPES; REFERENCE VALUES;

EID: 0029666402     PISSN: 09660844     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF00817919     Document Type: Article

References (23)

1. Barton JC. 1987 The absorption of metals as a function of age. In: Gerber GB, Métivier H, Smith H, eds. Age-related Factors in Radionuclide Metabolism and Dosimetry. Dordrecht: Martinus Nijhoff; 1-12.
2. Day JP, Barker J, Evans LJA, et al. 1991 Aluminium absorption studied by A1-26 tracer. Lancet 337, 1345.
3. 26Al and accelerator mass spectrometry. Nucl Instrum Methods Phys Res B92, 463-468.
4. DeBroe ME, van de Vyver F. 1985 Aluminium: a clinical problem in nephrology. Clin Nephrol 24, Suppl 1.
5. Doll R. 1993 Review: Alzheimers disease and environmental aluminium. Age and Aging 22, 138-153.
6. Edwardson JA, Moore PB, Ferner IN, et al. 1993 Effect of silicon on gastrointestinal absorption of aluminium. Lancet 342, 211-212.
7. Ganrot PO. 1986 Metabolism and possible health effects of aluminium. Environ Health Perspect 65, 363-441.
8. Greger JL, Baier MJ. 1983 Excretion and retention of low or moderate levels of aluminium by human subjects. Food Chem Toxicol 21, 473-477.
9. Haram E-MR, Weberg R, Berstad A. 1987 Urinary excretion of aluminium after ingestion of sucralfate and an aluminium-containing antacid in man. Scan J Gastroenterol 22, 615-618.
10. International Commission on Radiological Protection. 1981 Publication 30. Ann ICRP 6, 2/3.
11. International Commission on Radiological Protection. 1991. Publication 60. Ann ICRP 21, 1/3.
12. Métivier H, Fritsch P, Lataillade G. 1987 General considerations regarding intestinal absorption of radionuclides as a function of age. In: Gerber GB, Métivier H, Smith H, eds. Age-related Factors in Radionuclide Metabolism and Dosimetry. Dordrecht: Martinus Nijhoff; 13-20.
13. Partridge NA, Regnier FE, Reed WM, et al. 1992 Contribution of soluble aluminium species to absorption of aluminium from the rat gut in situ. Clin Sci 83, 425.
14. Priest ND, Newton D, Talbot RJ. 1991. Metabolism of aluminium-26 and gallium-67 in a volunteer following their injection as citrates. United Kingdom Atomic Energy Authority Report, AEA Technology, AEA-EE-0206.
15. Priest ND. 1993 The bioavailability and metabolism of aluminium in man. Proc Nutrit Soc 52, 231-240.
16. Priest ND. 1994 A human volunteer feeding study using aluminium-26 labelled aluminium citrate, aluminium hydroxide and aluminium hydroxide in the presence of citrate. United Kingdom Atomic Energy Authority Report, AEA Technology, AEA-TPD-268.
17. Priest ND, Newton D, Day JP, Talbot RJ, Warner AJ. 1995a Human metabolism of aluminium-26 and gallium-67 injected as citrates. Human Exp Toxicoi 14, 287-293.
18. Priest ND, Talbot RJ, Austin JG. 1995b The bioavailability in young adults of aluminium ingested in drinking water. United Kingdom Atomic Energy Authority Report, AEA Technology, AEA-TPD-269.
19. Talbot RJ, Newton D, Priest ND, Austin JG, Day JP. 1995 Intersubject variability in the metabolism of aluminium following intravenous injection as citrate. Human Exp Toxicol 14, 595-599.
20. van de Vyver F, Visser WJ. 1990 Aluminium accumulation in bone. In Priest ND, van de Vyver F, eds. Trace Metals and Fluoride in Bones and Teeth. Boca Raton: CRC Press; 83.
21. Webert R, Berstad A. 1986 Gastrointestinal absorption of aluminium from single doses of aluminium containing antacids in man. Eur J Clin Invest 16, 428-432.
22. Wilhelm M, Jäger E, Ohnesorge FK. 1990 Aluminium toxicokinetics. Pharmacol Toxicol 66, 4-9.
23. World Health Organization. 1972 The Use of Ionizing Radiation in Humans for Medical Research and Training, Including the Use of Radioactive Materials. Geneva: WHO.