The role of prostaglandins E2 and F(2α) in ultraviolet radiation-induced cortical cataracts in vivo

Investigative Ophthalmology and Visual Science

Volumn 37, Issue 8, 1996, Pages 1539-1548

  Andley, Usha P ^a   Fritz, Carol ^a   Morrison, Aubrey R ^a   Becker, Bernard ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

cataract; indomethacin; lens; prostaglandins; radiation; ultraviolet

Indexed keywords

6 OXOPROSTAGLANDIN F1 ALPHA; 8 BROMO CYCLIC AMP; ARACHIDONIC ACID; BUCLADESINE; FORSKOLIN; INDOMETACIN; MISOPROSTOL; N(G) NITROARGININE METHYL ESTER; POTASSIUM PUMP; PROSTAGLANDIN E2; PROSTAGLANDIN F2 ALPHA; PROSTAGLANDIN SYNTHASE; ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); EYE DROPS; OXYTOCIC AGENT; POTASSIUM; PROSTAGLANDIN SYNTHASE INHIBITOR; RUBIDIUM;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AQUEOUS HUMOR; ARACHIDONIC ACID METABOLISM; ARTICLE; CATARACT; CILIARY BODY; CONTROLLED STUDY; DRUG EFFECT; INTRAPERITONEAL DRUG ADMINISTRATION; IRIS; MASS SPECTROMETRY; NONHUMAN; PRIORITY JOURNAL; PROSTAGLANDIN SYNTHESIS; RABBIT; RADIATION CATARACT; SLIT LAMP; TOPICAL DRUG ADMINISTRATION; ULTRAVIOLET B RADIATION; ANIMAL; CHEMISTRY; CONJUNCTIVA; CORNEA; LENS; METABOLISM; PATHOPHYSIOLOGY; PHYSIOLOGY; RADIATION EXPOSURE; RADIATION INJURY; ULTRAVIOLET RADIATION;

6-KETOPROSTAGLANDIN F1 ALPHA; ANIMALS; CATARACT; CILIARY BODY; CONJUNCTIVA; CORNEA; CYCLOOXYGENASE INHIBITORS; DINOPROST; DINOPROSTONE; INDOMETHACIN; IRIS; LENS CORTEX, CRYSTALLINE; MISOPROSTOL; NA(+)-K(+)-EXCHANGING ATPASE; OPHTHALMIC SOLUTIONS; OXYTOCICS; POTASSIUM; RABBITS; RADIATION INJURIES, EXPERIMENTAL; RUBIDIUM RADIOISOTOPES; ULTRAVIOLET RAYS;

EID: 0029666393     PISSN: 01460404     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (43)

1. Pitts DG, Parr WH. Ocular ultraviolet effects from 295 nm to 335 nm in the rabbit eye. In: National Institute for Occupational Safety and Health Technical Information. Washington, DC: US Department of Health, Education and Welfare Publication No. 77-130; 1976:1-55.
2. Jose J, Pitts DG. Wavelength dependency of cataracts in albino mice following chronic exposure. Exp Eye Res. 1986;41:545-563.
3. Pitts DG, Cullen AP, Hacker PD. The ocular effects of ultraviolet radiation from 295 to 365 nm. Invest Ophthalmol Vis Sci. 1977;16:932-939.
4. Zigman S. Photochemical mechanisms in cataract formation. In: Duncan G, ed. Mechanism of Cataract Formation in Human Lens. London: Academic Press; 1981;117-150.
5. Andley UP. Biochemistry of the crystalline lens: Photooxidative stress. In: Albert DM, Jakobiec FA, eds. Principles and Practice of Ophthalmology: Clinical Practice. Vol. 1. Philadelphia: WB Saunders; 1994:575-590.
6. Taylor HR, West SK, Rosenthal FS, et al. Effect of ultraviolet radiation in cataract formation. N Engl J Med. 1988;319:1429-1433.
7. Dolin PJ. Ultraviolet radiation and cataract: A review of the epidemiological evidence. Br J Ophthalmol. 1994;78:478-482.
8. Miller CC, Hale P, Pentland AP. Ultraviolet B injury increases prostaglandin synthesis through a tyrosine kinase-dependent pathway: Evidence for UVB-induced epidermal growth factor receptor activation. J Biol Chem. 1994;269:3529-3533.
9. Devary Y, Gottlieb R, Smeal T, Karin M. The mammalian ultraviolet response is triggered by activation of src tyrosine kinases. Cell. 1992;71:1081-1091.
10. Andley UP, Hebert JS, Morrison AR, Reddan JR, Pentland AP. Modulation of lens epithelial cell proliferation by enhanced prostaglandin synthesis after UVB exposure. Invest Ophthalmol Vis Sci. 1994;35:374-381.
11. Andley UP, Becker B, Hebert JS, Morrison AR, Reddan JR, Pentland AP. Enhanced prostaglandin synthesis after UVB exposure of lens epithelial cells modulates DNA synthesis and lowers intraocular pressure in vivo. Invest Ophthalmol Vis Sci. 1996;37:142-153.
12. Nishi O, Nishi K, Imanishi M, Toda Y, Shirasawa E. Effect of the cytokines on the prostaglandin E2 synthesis by lens epithelial cells of human cataracts. Br J Ophthalmol. 1995;79:934-938.
13. Zelenka PS. Lens lipids. Curr Eye Res. 1984;3:1337-1357.
14. Zelenka PS. Changes in phosphatidylinositol metabolism during differentiation of lens epithelial cells into lens fiber cells in the embryonic chick. J Biol Chem. 1980;255:1296-1300.
15. Vivekanandan S, Lou MF. Evidence for the presence of phosphoinositide cycle and its involvement in cellular signal transduction in the rabbit lens. Curr Eye Res. 1989;8:101-111.
16. Keating PE, Lysz TW, Centra M, Fu SCJ. Prostaglandin biosynthesis in the rat lens. Invest Ophthalmol Vis Sci. 1985;26:1083-1086.
17. Bazan HEP. The synthesis and effects of eicosanoids in avascular tissues. In: Bito LZ, Stjernschantz J, eds. The Ocular Effects of Prostaglandins and Other Eicosanoids. New York: Alan R Liss; 1989:73-84.
18. Lysz TW, Lin C, Fu SCJ, Wu Y. Temporal and regional production of 12(S)hydroxyeicosatetraenoic acid [12(S)-HETE] in rat lens. Exp Eye Res. 1992;54:769-774.
19. Zheng D-R, Fu S-CJ, Lysz TW, Leung CCK. Immunocytochemical localization of cyclooxygenase in the rat lens. Invest Ophthalmol Vis Sci. 1992;33:178-183.
20. Blaytny R, Harding JJ. Prevention of cataract in diabetic rats by aspirin, paracetamol (acetaminophen) and ibuprofen. Exp Eye Res. 1992;54:509-518.
21. Seddon JM, Christen WG, Manson JE, Buring JE, Sperduto RD, Hennekens CH. Low dose aspirin and risks of cataract in a randomized trial of US physicians. Arch Ophthalmol. 1991;109:252-255.
22. Harding JJ. Aspirin and cataract Arch Ophthalmol 1991;109:1334.
23. Pentland AP, Mahoney M, Jacobs SC, Holtzman MJ. Enhanced prostaglandin synthesis after ultraviolet injury is mediated by endogenous histamine stimulation: A mechanism for irradiation erythema. J Clin Invest. 1990;86:566-574.
24. Coyne DW, Nickols M, Berfrad W, Morrison AR. Regulation of mesangial cells cyclooxygenase synthesis by cytokines and glucocorticoids. Am J Physiol (Renal Fluid Electrolyte Physiol 32). 1992;263:F97-F102.
25. Becker B. Accumulation of rubidium-86 by the rabbit lens. Invest Ophthalmol. 1962;1:502-506.
26. Becker B, Cotlier E. Distribution of rubidium-86 accumulated in the rabbit lens. Invest Ophthalmol. 1962; 1:642-645.
27. Salvemini D, Misko TP, Masferrer JL, Seibert K, Currie MG, Needleman P. Nitric oxide activates cyclooxygenase enzymes. Proc Natl Acad Sci USA. 1993;90:7240-7244.
28. Kuehl FA, Egan RW. Prostaglandins, arachidonic acid and inflammation. Science. 1980;210:978-984.
29. Neufeld AH, Jampol LM, Sears ML. Aspirin prevents the disruption of blood-aqueous barrier in the rabbit eye. Nature. 1972;238:158-159.
30. Matsuda H, Giblin FJ, Reddy VN. The effect of X-irradiation on cation transport in rabbit lens. Exp Eye Res. 1981;33:253-265.
31. Smith WL, Marnett LJ, Dewitt DL. Prostaglandin and thromboxane biosynthesis. Pharmacol Ther. 1991;49: 151-179.
32. 2+ signals in Swiss 3T3 cells. Biochem Pharmacol. 1994;47:1567-1574.
33. 2. Am J Physiol. 1978;235: E703-E707.
34. 2 protects cultured cortical neurons against N-methyl-D-aspartate receptor-mediated glutamate cytotoxicity. Brain Res. 1994;663:237-243.
35. 2: A mediator of corneal endothelial wound repair in vitro. Am J Physiol (Cell Physiol 35). 1994;266:C269-C275.
36. Krisberg JI, Patel PY, Venkatachalam MA, Taylor G. Elevation of intracellular cAMP results in a change in cell shape that resembles dome formation in cultured rat glomerular epithelial cells. In Vitro Cell Dev Biol. 1986;22:392-396.
37. Gotleib AI. Prostaglandin induced shape change in fibroblasts grown in culture. Prostaglandins. 1980;19: 865-871.
38. Srinivasan BD, Kulkarni PS. The role of arachidonic acid metabolites in the mediation of polymorphonuclear leukocyte responses following corneal injury. Invest Ophthalmol Vis Sci. 1980;19:1087-1093.
39. Godar DE, Miller SA, Thomas DP. Immediate and delayed apoptotic cell death mechanisms: UVA versus UVB and UVC radiation. Cell Death and Differentiation. 1994;1:59-66.
40. Pierce KL, Gil DW, Woodward DF, Regan JW. Cloning of human prostanoid receptors. Trends Pharmacol Sci. 1995;16:253-256.
41. 2α ester prodrugs and receptor selective prostaglandin analogs. J Ocul Pharmacol. 1994;10:177-193.
42. Coleman RA, Kennedy I, Humphrey PPA, Bunce K, Lumley P. Prostanoids and their receptors. In: Hausch C, Sammes PG, Taylor JB, et al. Comprehensive Medicinal Chemistry. Vol. 3. New York: Pergamon Press; 1990: 693-714.
43. 2α-1-isopropyl ester applied in multiple doses in ocular hypertensive and glaucoma patients. Ophthalmology. 1989;96:1329-1337.