Homozygous deletions of pl6/MTS1 and p15/MTS2 genes are frequent in t(1;19)-negative but not in t(1;19)-positive B precursor acute lymphoblastic leukemia in childhood

Leukemia

Volumn 10, Issue 7, 1996, Pages 1104-1110

  Ohnishi, H ^a   Hanada, R ^b   Horibe, K ^c   Hongo, T ^d   Kawamura, M ^a   Naritaka, S ^a   Bessho, F ^a   Yanagisawa, M ^a   Nobori, T ^e   Yamamori, S ^f   Hayashi, Y ^a  

^a UNIVERSITY OF TOKYO   (Japan)

^b SAITAMA CHILDREN'S MEDICAL CENTER   (Japan)

^c NAGOYA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^d HAMAMATSU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^e UNIVERSITY OF CALIFORNIA   (United States)

^f Mitsubishi Kagaku Biochem Labs   (Japan)

Author keywords

Acute lymphoblastic leukemia; Childhood; E2a; p16; t(1; 19)

Indexed keywords

ACUTE LYMPHOBLASTIC LEUKEMIA; ARTICLE; CHILDHOOD LEUKEMIA; CODON; GENE DELETION; GENE REARRANGEMENT; HOMOZYGOSITY; HUMAN; HUMAN CELL; MISSENSE MUTATION; NONSENSE MUTATION; PRIORITY JOURNAL; ACUTE LYMPHOCYTIC LEUKEMIA; B CELL LEUKEMIA; CHILD; CHROMOSOME 1; CHROMOSOME 19; GENE TRANSLOCATION; GENETICS; HOMOZYGOTE; MOLECULAR GENETICS; MUTATION; NUCLEOTIDE SEQUENCE; POLYMERASE CHAIN REACTION; SINGLE STRAND CONFORMATION POLYMORPHISM; SOUTHERN BLOTTING; TUMOR SUPPRESSOR GENE;

CARRIER PROTEIN; CDKN2B PROTEIN, HUMAN; CELL CYCLE PROTEIN; CYCLIN DEPENDENT KINASE INHIBITOR 2B; PROTEIN P16INK4A; TUMOR SUPPRESSOR PROTEIN;

BASE SEQUENCE; BLOTTING, SOUTHERN; CARRIER PROTEINS; CELL CYCLE PROTEINS; CHILD; CHROMOSOMES, HUMAN, PAIR 1; CHROMOSOMES, HUMAN, PAIR 19; CYCLIN-DEPENDENT KINASE INHIBITOR P15; CYCLIN-DEPENDENT KINASE INHIBITOR P16; GENE DELETION; GENES, TUMOR SUPPRESSOR; HOMOZYGOTE; HUMANS; LEUKEMIA, LYMPHOCYTIC, ACUTE, L1; LEUKEMIA, PRE-B-CELL; MOLECULAR SEQUENCE DATA; MUTATION; POLYMERASE CHAIN REACTION; POLYMORPHISM, SINGLE-STRANDED CONFORMATIONAL; TRANSLOCATION, GENETIC; TUMOR SUPPRESSOR PROTEINS;

EID: 0029666314     PISSN: 08876924     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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