Characterization of IκB kinases: IκB-α is not phosphorylated by Raf-1 or protein kinase C isozymes, but is a casein kinase II substrate

Journal of Biological Chemistry

Volumn 271, Issue 23, 1996, Pages 13868-13874

  Janosch, Petra ^a   Scheuerer, Miriam ^a   Seitz, Thomas ^a   Reim, Peter ^a   Eulitz, Manfred ^a   Brielmeier, Markus ^a   Kölch, Walter ^a   Sedivy, John M ^b   Mischak, Harald ^a  

^a Inst F Klin Molekularbiologie T   (Germany)

^b BROWN UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INSECTA; SUIDAE;

CASEIN KINASE II; DNA BINDING PROTEIN; I KAPPA B; I KAPPA B KINASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; ISOENZYME; NF KAPPAB INHIBITOR ALPHA; NF-KAPPAB INHIBITOR ALPHA; ONCOPROTEIN; PROTEIN KINASE C; PROTEIN SERINE THREONINE KINASE; RAF PROTEIN; RECOMBINANT PROTEIN; CASEIN KINASE; INHIBITOR PROTEIN; TRANSCRIPTION FACTOR;

AMINO ACID SEQUENCE; ANIMAL; ARMYWORM; ARTICLE; BACULOVIRUS; CELL LINE; CHEMISTRY; ENZYME SPECIFICITY; GENETICS; IN VITRO STUDY; METABOLISM; MOLECULAR GENETICS; PHOSPHORYLATION; SWINE; ANIMAL CELL; ENZYME ACTIVATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; PROTEIN PURIFICATION; TRANSCRIPTION INITIATION;

AMINO ACID SEQUENCE; ANIMALS; BACULOVIRIDAE; CASEIN KINASE II; CELL LINE; DNA-BINDING PROTEINS; I-KAPPA B KINASE; I-KAPPA B PROTEINS; ISOENZYMES; MOLECULAR SEQUENCE DATA; NF-KAPPA B; PHOSPHORYLATION; PROTEIN KINASE C; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-RAF; RECOMBINANT PROTEINS; SPODOPTERA; SUBSTRATE SPECIFICITY; SWINE;

EID: 0029666261     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.271.23.13868     Document Type: Article

References (21)

1. Thanos, D., and Maniatis, T. (1995) Cell 80, 529-532
2. Siebenlist, U., Brown, K., and Franzoso, G. (1995) in Inducible Gene Expression (Baeuerle, P. A., ed) Vol. 1, pp. 93-141, Birkhaeuser Boston, Inc., Cambridge
3. Baeuerle, P. A., and Henkel, T. (1994) Annu. Rev. Immunol. 12, 141-179
4. Traeckner, E. B.-M., Pahl, H. L., Henkel, T., Schmidt, K. N., Wilk, S., and Baeuerle, P. A. (1994) EMBO J. 14, 2876-2883
5. Chen, Z., Hagler, J., Palombella, V. J., Melandri, F., Scherer, D., Ballard, D., and Maniatis, T. (1995) Genes Dev. 9, 1586-1597
6. Brown, K., Gerstberger, S., Carlson, L., Franzoso, G., and Siebenlist, U. (1994) Science 267, 1485-1488
7. Barroga, C. F., Stevenson, J. K., Schwarz, E. M., and Verma, I. M. (1995) Proc. Natl. Acad. Sci. U. S. A. 92, 7637-7641
8. McElhinny, J. A., Trushin, S. A., Bren, G. D., Chester, N., and Paya, C. V. (1996) Mol. Cell. Biol. 16, 899-906
9. Gosh, S., and Baltimore, D. (1990) Nature 844, 678-682
10. Goodnight, J., Mischak, H., and Mushinski, J. F. (1994) Adv. Cancer Res. 68, 159-209
11. Lozano, J., Berra, E., Municio, M. M., Diaz-Meco, M.-T., Dominguez, I., Sanz, L., and Moscat, J. (1994) J. Biol. Chem. 269, 19200-19202
12. Wiegmann, K., Schütze, S., Machleidt, T., Witte, D., and Krönke, M. (1994) Cell 78, 1005-1015
13. Mischak, H., Goodnight, J., Kolch, W., Martiny-Baron, G., Schæchtle, C., Kazanietz, M. G., Blumberg, P. M., Pierce, J. H., and Mushinski, J. F. (1993) J. Biol. Chem. 268, 6090-6096
14. Mischak, H., Pierce, J. H., Goodnight, J., Kazanietz, M. G., Blumberg, P. M., and Mushinski, J. F. (1993) J. Biol. Chem. 268, 20110-20115
15. Kazanietz, M. G., Areces, L. B., Bahador, A., Mischak, H., Goodnight, J., Mushinski, J. F., and Blumberg, P. M. (1993) Mol. Pharmacol. 44, 298-307
16. Huang, K.-P., and Huang, F. L. (1991) Methods Enzymol. 200, 241-252
17. Häfner, S., Adler, H., Mischak, H., Janosch, P., Heidecker, G., Wolfman, A., Pippig, S., Lohse, M., Offing, M., and Kölch, W. (1994) Mol. Cell. Biol. 14, 6696-6703
18. Kölch, W., Heidecker, G., Kochs, G., Vahidi, H., Mischak, H., Finkenzeller, G., Hummel, R., Marmee, D., and Rapp, U. R. (1993) Nature 364, 249-252
19. Mischak, H., Bodenteich, A., Kolch, W., Goodnight, J., Hofer, F., and Mushinski, J. F. (1991) Biochemistry 30, 7925-7931
20. Hathaway, G. M., Lubben, T. H., and Traugh, J. A. (1980) J. Biol. Chem. 265, 8038-8041
21. Li, S., and Sedivy, J. M. (1993) Proc. Natl. Acad. Sci. U. S. A. 90, 9247-9251