Stability of Revex™, nalmefene hydrochloride injection

PDA Journal of Pharmaceutical Science and Technology

Volumn 50, Issue 1, 1996, Pages 35-39

  Brittain, Harry G ^a,b   Lafferty, Linda ^a   Bousserski, Petranna ^a   Diegnan, Glenn ^a   Lessor, Ralph ^a   Small, Camille ^a   Pejaver, Satish ^a  

^a Ohmeda Inc   (United States)

^b NONE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DRUG DERIVATIVE; NALMEFENE; NALTREXONE; NARCOTIC ANTAGONIST;

ARTICLE; DRUG STABILITY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; ANALYTIC METHOD; DRUG POTENCY; HUMAN; HYPOTENSION; INTRAMUSCULAR DRUG ADMINISTRATION; RESPIRATION DEPRESSION; SEDATION; STRUCTURE ANALYSIS;

CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DRUG STABILITY; NALTREXONE; NARCOTIC ANTAGONISTS;

EID: 0029666226     PISSN: 10797440     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (9)

1. Key Pharmaceuticals, "Nalmefene - narcotic antagonist," Drugs Of The Future, 9, 624 (1984); ibid., 10, 600-601 (1985); ibid., 12, 722-723 (1987); ibid., 15, 755-756 (1990).
2. Key Pharmaceuticals, "Nalmefene - narcotic antagonist," Drugs Of The Future, 9, 624 (1984); ibid., 10, 600-601 (1985); ibid., 12, 722-723 (1987); ibid., 15, 755-756 (1990).
3. Key Pharmaceuticals, "Nalmefene - narcotic antagonist," Drugs Of The Future, 9, 624 (1984); ibid., 10, 600-601 (1985); ibid., 12, 722-723 (1987); ibid., 15, 755-756 (1990).
4. Key Pharmaceuticals, "Nalmefene - narcotic antagonist," Drugs Of The Future, 9, 624 (1984); ibid., 10, 600-601 (1985); ibid., 12, 722-723 (1987); ibid., 15, 755-756 (1990).
5. R. Nagarajan, S. Jeyashree, and M. Shanmaugam, "Reversal of effects of morphine by nalmefene," J. Clin. Res. Drug Dev., 7, 25-29 (1993).
6. R. Dixon, J. Howes, and J. Gentile, "Nalmefene: intravenous safety and kinetics of a new opioid antagonist," Clin. Pharmacol. Ther., 39, 49-53 (1986).
7. International Research and Development Corporation, "Bisnalmefene succinate: acute intravenous toxicity study in mice," Study 530-035, completed October, 1993.
8. United States Pharmacopeia, "Validation of compendial methods," general test, USP23-NF18 (1995), pp. 1982-1984.
9. H.-L. Fung, "Chemical kinetics and drug stability," in Modern Pharmaceutics, G. S. Banker and C. T. Rhodes, eds, Marcel Dekker, Inc., New York, 1979, pp. 246-248.